A5030784069- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Catalysis for Biomass Conversion
- Flame retardant materials and properties
- Biofuel production and bioconversion
- Layered Double Hydroxides Synthesis and Applications
- Carbon dioxide utilization in catalysis
- biodegradable polymer synthesis and properties
- Luminescence and Fluorescent Materials
- Fire dynamics and safety research
- Essential Oils and Antimicrobial Activity
- Crystallization and Solubility Studies
- Biochemical and biochemical processes
- Chemical Synthesis and Reactions
- Ionic liquids properties and applications
- Chemical and Physical Properties in Aqueous Solutions
- X-ray Diffraction in Crystallography
- Phytochemistry and Biological Activities
- Nanoparticle-Based Drug Delivery
- Enzyme Catalysis and Immobilization
- Magnolia and Illicium research
- Psoriasis: Treatment and Pathogenesis
- Antifungal resistance and susceptibility
- Clay minerals and soil interactions
- Polydiacetylene-based materials and applications
Beijing University of Chinese Medicine
2025
Hunan University of Science and Engineering
2022-2024
Southern Medical University
2020-2024
Fudan University
2024
China University of Petroleum, East China
2022
Zhejiang University of Technology
2022
Sun Yat-sen University
2014-2018
Institute of Coal Chemistry
2017-2018
University of Chinese Academy of Sciences
2017-2018
Chinese Academy of Sciences
2018
Abstract Raman spectroscopy using surface-enhanced scattering (SERS) nanoprobes represents an ultrasensitive and high-precision technique for in vivo imaging. Clinical translation of SERS has been hampered by biosafety concerns about the metal substrates used to enhance signals. We report a set small molecules with bis-thienyl-substituted benzobisthiadiazole structures that signal through self-stacking rather than external substrates. In our technique, called stacking-induced charge...
Development of lysosomes and mitochondria dual-targeting photosensitizer with the virtues near-infrared (NIR) emission, highly efficient reactive oxygen generation, good phototoxicity biocompatibility is desirable in field imaging-guided photodynamic therapy (PDT) for cancer. Herein, a new positively charged amphiphilic organic compound (2-(2-(5-(7-(4-(diphenylamino)phenyl)benzo[c] [1,2,5]thiadiazol-4-yl)thiophen-2-yl)vinyl)-3-methylbenzo[d]thiazol-3-ium iodide) (ADB) based on D-A-π-A...
To increase the effectiveness of using typical biomass waste as a resource, iridoids, chlorogenic acid, and flavonoids from Eucommia ulmoides leaves (EULs) were extracted by deep eutectic solvents (DESs) in conjunction with macroporous resin. optimize extract conditions, experiment response surface was employed single-factor DES composition molar ratio, liquid–solid water percentage, extraction temperature, time. The findings demonstrated that theoretical simulated yield acid (CGA),...
Background The incidence of nosocomial candidemia has increased in recently years, however, the epidemiological data remain insufficient China. Methods A total 234 patients were included from Xiamen University Zhong Shan hospital between January 2006 and October 2024. Incidence, species proportion, distribution, antifungal drug resistance was analyzed. nomogram model for 30-day morbidity determined using least absolute shrinkage logistic regression analysis. Results recent years (2020:...
Photosensitizers play a critical role in photodynamic therapy (PDT). Multifunctional organic nanoparticles (NPs) that possess bright fluorescence aggregates, high singlet oxygen (1O2) quantum yield, near-infrared (NIR) absorption and emission, large Stokes shift, two-photon bioimaging, specific organelle targeting, PDT efficiency, as well good biocompatibility photostability are ideal candidate photosensitizers for image-guided PDT. Due to its enhanced 1O2 generation efficiency aggregate...
Lymphatic metastasis plays an important role in tumour recurrence. The applications of nanoparticles the treatment lymphatic metastatic tumours have been limited by targeting inefficiency and nonselective toxicity. Hence, this report, we developed lipid-coated ZnO (LZnO NPs) attempt to solve these issues. Using microreactor method, fabricated ultrasmall (∼30 nm) core-shell-structured loaded with 6-mercaptopurine (6-MP). In vivo results show that lipid shell induces a remarkable improvement...
Hyperproliferative keratinocytes and subcutaneous inflammation contribute to the characteristic symptoms of psoriasis, including erythema, scales, or scaly plaques on skin. These significantly affect patients’ quality life cause severe physical psychological distress. However, current treatment strategies have limited therapeutic effect may lead adverse side effects. In this study, we present novel organic photosensitizer TBTDC...
Abstract: Layered double hydroxide (LDH) has attracted considerable attention as a drug carrier. However, because of its poor in vivo behavior, polyethylene glycolylated (PEGylated) phospholipid must be used coformer to produce self-assembled core–shell nanoparticles. In the present study, we prepared PEGylated phospholipid-coated LDH (PLDH) (PEG-PLDH) delivery system. The PEG-PLDH nanoparticles had an average size 133.2 nm. Their structure was confirmed by transmission electron microscopy...
The Ca-Al and Ca-Al-X (X = F-, Cl- Br-) catalysts were prepared via thermal decomposition of layered double hydroxides (LDHs), tested for methanolysis propylene carbonate (PC) to produce dimethyl (DMC). catalytic performance these increased in the order Ca-Al-Br- < Ca-Al-Cl- Ca-Al-F-, which was consistent with strong basicity materials. recyclability test results showed that addition Al halogens (F-, not only stabilized CaO but also improved catalysts. Particularly, Ca-Al-F- catalyst exerted...
The aim of the present study was to develop layered double hydroxide (LDH) nanoparticles coated with PEGylated phospholipid membrane. By comparing size distribution and zeta potential, weight ratio LDH lipid materials which constitute outside membrane identified as 2:1. Transmission electron microscopy photographs confirmed core-shell structure (PEG-PLDH) nanoparticles, cell cytotoxicity assay showed their good viability on Hela BALB/C-3T3 cells over concentration range from 0.5 50 μg/mL.
This study aimed to convert wastes generated during the extraction of oil from Camellia oleifera seeds, including fruit shell (COFS) and seed cake (COSC), into fermentable feedstocks using pretreatment enzymatic hydrolysis processes. The application a green acid catalyst in thermochemical COFS COSC mixture yielded highest sugar 28 g/L. Solid-state fermentation (SSF) was conducted on-site various waste biomass substrates produce enzymes for saccharification process. found that ideal substrate...
Lignanoids are an active ingredient exerting powerful antioxidant and anti-inflammatory effects in the treatment of many diseases. In order to improve efficiency resource utilization traditional Chinese medicine waste, Magnolia officinalis Rehder & E.H.Wilson residue (MOR) waste biomass was used as raw material this study, a series deep eutectic solvents (ChUre, ChAce, ChPro, ChCit, ChOxa, ChMal, ChLac, ChLev, ChGly ChEG) were selected evaluate extraction lignanoids from MORs. The...