A5100327341- interferon and immune responses
- Cytomegalovirus and herpesvirus research
- Plant Reproductive Biology
- Plant Virus Research Studies
- Plant Molecular Biology Research
- Immune Cell Function and Interaction
- Plant nutrient uptake and metabolism
- Circular RNAs in diseases
- Crop Yield and Soil Fertility
- Microbial Metabolism and Applications
- Plant pathogens and resistance mechanisms
- Advanced Photocatalysis Techniques
- Tryptophan and brain disorders
- Plant-Microbe Interactions and Immunity
- Gut microbiota and health
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Fungal Plant Pathogen Control
- Aquaculture Nutrition and Growth
- Research in Cotton Cultivation
- Antimicrobial agents and applications
- Enzyme-mediated dye degradation
- Invertebrate Immune Response Mechanisms
Guangdong Ocean University
2025
Henan University
2017-2024
Ningbo University
2024
Shaanxi Normal University
2024
ShanghaiTech University
2021-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Sanya University
2023
Hunan University
2015-2022
State Key Laboratory of Chemobiosensing and Chemometrics
2017-2022
Nanjing Drum Tower Hospital
2020-2021
The molecular mechanisms controlling organ size during plant development ultimately influence crop yield. However, a deep understanding of these is still lacking. UBIQUITIN-SPECIFIC PROTEASE14 (UBP14), encoded by DA3, an essential factor determining in Arabidopsis (Arabidopsis thaliana). Here, we identified two suppressors the da3-1 mutant phenotype, namely SUPPRESSOR OF 1 and 2 (SUD1 SUD2), which encode E3 ligases MOS4-ASSOCIATED COMPLEX 3A (MAC3A) MAC3B, respectively. mac3a-1 mac3b-1...
Receptor-like kinases (RLKs) constitute the largest receptor family involved in regulation of plant immunity and growth, but small-molecule inhibitors that target RLKs to improve agronomic traits remain unexplored. The RLK member FERONIA (FER) negatively regulates resistance certain soil-borne diseases are difficult control cause huge losses crop yields economy. Here, we identified 33 highly effective FER kinase from 1494 small molecules by monitoring autophosphorylation vitro. Four...
A series of novel pyrazole amide derivatives 3a-3p which take TMV PC protein as the target has been designed and synthesized by reactions 5-chloro-1-aryl-3-methyl-1H-pyrazole-4-carboxylic acids with 5-amino-1-aryl-1H-pyrazole-4-carbonitriles. All compounds were characterized 1H-NMR, mass spectroscopy elemental analysis. Preliminary bioassays indicated that all acted against tobacco mosaic virus (TMV) different in vivo vitro modes at 500 μg/mL found to possess promising activity. Especially,...
Soybean [ Glycine max (L.) Merr. ] is one of the most strategical oilseed crops that provides sustainable source protein and oil worldwide. Cultivation soybean severely affected by root-knot nematode (RKN). However, mechanism RKN parasitism to soybeans largely unknown. In this study, we identify GmLMM1 , which encodes a homolog FERONIA-like receptor kinase in soybean, as susceptible gene toward nematode. Mutations exhibit enhanced resistance against Meloidogyne incognita . RNA-sequencing...
Bacillus licheniformis has been found to be one of the persistent dominant microorganisms in Daqu, which is a traditional fermentation starter, and it used intensify certain strains. To understand impact B. on behaviour was studied using 1H NMR-based non-targeted analysis principal component analysis. During fermentation, 53 compounds were identified. Among them, seven largely consumed 17 metabolites accumulated. The macromolecular starch cellulose degraded by licheniformis, then utilized...
Plant shoot phototropism is triggered by the formation of a light-driven auxin gradient leading to bending growth. The blue light receptor phototropin 1 (phot1) senses direction, but how this leads and growth regulation remains poorly understood. Previous studies have suggested phot1's role for regulated apoplastic acidification, its relation hypocotyl unclear. Herein, we show that can cause phot1 interact with phosphorylate FERONIA (FER), known cell regulator, trigger downstream phototropic...
Reactive astrocytes play critical roles in the occurrence of various neurological diseases such as multiple sclerosis. Activation is often accompanied by a glycolysis-dominant metabolic switch. However, role and molecular mechanism reprogramming activation have not been clarified. Here, we found that PKM2, rate-limiting enzyme glycolysis, displayed nuclear translocation EAE (experimental autoimmune encephalomyelitis) mice, an animal model Prevention PKM2 import DASA-58 significantly reduced...
Verticillium wilt (VW) caused by dahliae (V. dahliae) is one of the most destructive diseases in cotton (Gossypium spp.). Histone acetylation plays critical roles plant development and adaptive responses to biotic abiotic stresses. However, relevance histone VW resistance remains largely unclear. Here, we identified Deacetylase 5 (GhHDA5) from upland hirsutum L.), as a negative regulator resistance. GhHDA5 expression was responsive V. infection. Silencing led improved dahliae, while...
Individuals with subjective cognitive decline (SCD) are at higher risk of incipient Alzheimer's disease (AD). Spatial navigation (SN) impairments in AD dementia and mild impairment patients have been well-documented; however, studies investigating SN deficits SCD subjects still lacking. This study aimed to explore whether basal forebrain (BF) entorhinal cortex (EC) atrophy contribute spatial disorientation the stage. In total, 31 24 normal controls were enrolled administered scales, a...
Abstract Soil salinity poses a significant challenge to crop growth and productivity, particularly affecting the root system, which is vital for water nutrient uptake. To identify genetic factors that influence elongation in stressful environments, we conducted genome-wide association study (GWAS) investigate natural variation associated with total length (TRL) under salt stress normal conditions maize seedlings. Our identified 69 variants 38 candidate genes, among specific single nucleotide...