A5034350227- Hypothalamic control of reproductive hormones
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Estrogen and related hormone effects
- Reproductive Physiology in Livestock
- Growth Hormone and Insulin-like Growth Factors
- Hormonal and reproductive studies
- Reproductive System and Pregnancy
- Sperm and Testicular Function
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Neonatal Respiratory Health Research
- Nutrition, Genetics, and Disease
- FOXO transcription factor regulation
- Menopause: Health Impacts and Treatments
- Regulation of Appetite and Obesity
- Cancer Mechanisms and Therapy
- Inflammatory mediators and NSAID effects
- BRCA gene mutations in cancer
- Per- and polyfluoroalkyl substances research
- Epigenetics and DNA Methylation
- Electrolyte and hormonal disorders
- Phytoestrogen effects and research
- Bee Products Chemical Analysis
- Adipokines, Inflammation, and Metabolic Diseases
- Rabbits: Nutrition, Reproduction, Health
Mexican Social Security Institute
2002-2022
Centro Medico Nacional Siglo XXI
2005-2006
Hospital de Especialidades
2006
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
1995
In the present study we analyzed physiological changes in relative distribution of FSH isoforms circulating under baseline conditions throughout ovarian cycle as well forms discharged by GnRH stimulation from putative acutely releasable and reserve pituitary pools. Eight normally menstruating women underwent blood sampling on three occasions, once each during presumptive early or midfollicular phase (FP), late follicular to midcycle (preovulatory phase; PO), mid- luteal (LP) menstrual cycle....
Alterations in the reproductive axis function are present to a variable extent patients with type 1 diabetes mellitus (IDDM). Results from studies IDDM men have yielded discrepant findings, which may reflect nonuniform patient selection criteria, age, diabetic status, duration of disease and differences sampling protocols. To more clearly define impact early alterations male axis, we applied combined strategy restricted young relatively short IDDM, dual control groups, multiparameter...
Hormonal abnormalities of the reproductive axis have been described in obesity. In men, extreme obesity is associated with low serum testosterone (T) and high estrogen [estrone estradiol (E2)] levels. As changes sex steroid milieu may profoundly affect carbohydrate heterogeneity thus some biological physicochemical properties LH molecule, we analyzed relative distribution isoforms circulating under baseline conditions (endogenous GnRH drive) as well forms discharged by exogenous stimulation...
The immunoreactivity of various LH and FSH calibration standards recombinant preparations in the enzyme-linked immunoassay (EIA) systems for gonadotrophins developed Special Programme Research Human Reproduction World Health Organization (WHO) were compared. tested included three two pituitary (calibrated against 80/552 68/40 78/549 respectively) provided with EIA or radioimmunoassay WHO matched reagent kits, preparation LER-907, human (rhLH) (rhFSH). Simultaneous curve fitting dose-response...
ABSTRACT The purpose of this study was to investigate the effect 1,1,1‐trichloro‐2,2‐bis‐(chlorophenyl)ethane (DDT), 1,1‐bis‐(chlorophenyl)‐2,2‐dichloroethene (DDE), and 1,1‐dichloro‐2,2‐bis(chlorophenyl)ethane (DDD) isomers on COX‐2 expression in a human trophoblast‐derived cell line. Cultured HTR‐8/SVneo trophoblast cells were exposed DDT its metabolites for 24 h, mRNA protein assessed by RT‐PCR, Western blotting, ELISA. Prostaglandin E 2 production also measured Both detected under...
Numerous clinical studies have reported the association between high circulating levels of lipocalin-2 (LCN2) and metabolic diseases. However, only few addressed sexually dimorphic, either in its concentration or expression other organs. To best our knowledge, LCN2 24p3 receptor (24p3R), not been identified gonads; therefore, present study analyzed their mRNA profile cellular localization gonads collected from fetal rats at 21 days post coitum, as well neonatal 0, 2, 4, 6, 12, 20 30...
CATSPER1 gene encodes a pore-forming and pH-sensing subunit of the CatSper Ca2+- permeable channel, protein in flagellum essential for sperm hyperactivation. Previous studies have shown that murine Catsper1 promoter is regulated by different Sox proteins. Likewise, it acknowledged human sequence enriched potential interaction sites sex-determining region Y (SRY), which suggest novel regulatory transcriptional mechanism CatSper1 channel expression. Therefore, this work, we sought to determine...
The CatSper channel localizes exclusively in the flagella of sperm cells. Catsper1 protein, together with three pore units, is essential for Channel formation, which produces flagellum hyperactivation and confers fertility. expression dependent on Sox transcription factors, can recognize vitro at least binding sites promoter. factors have calmodulin-binding domains nuclear importation. Calmodulin (CaM) affected by specific inhibitor calmidazolium (CMZ), prevents transport factors. In this...