A5018349937- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Cardiac pacing and defibrillation studies
- Functional Brain Connectivity Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Acute Ischemic Stroke Management
- MicroRNA in disease regulation
- S100 Proteins and Annexins
- Ferroptosis and cancer prognosis
- interferon and immune responses
- Neurological disorders and treatments
- Growth Hormone and Insulin-like Growth Factors
- Neurosurgical Procedures and Complications
- Lymphoma Diagnosis and Treatment
- Liver physiology and pathology
- Glioma Diagnosis and Treatment
- Anesthesia and Neurotoxicity Research
- Peptidase Inhibition and Analysis
- Cancer-related molecular mechanisms research
- Bone Metabolism and Diseases
- Medical Research and Treatments
- Medical Imaging and Analysis
- Cardiac Arrest and Resuscitation
- Parkinson's Disease Mechanisms and Treatments
- Cardiac Fibrosis and Remodeling
Kunming Medical University
2008-2025
Yan'an Hospital Affiliated To Kunming Medical University
2024-2025
Stomatology Hospital
2024
Tianjin Medical University Cancer Institute and Hospital
2023
Eastern Hepatobiliary Surgery Hospital
2019-2022
Second Military Medical University
2014-2022
Shanghai Changzheng Hospital
2017-2018
The First Hospital of Kunming
2016
Southwest University
2014
Panzhihua Central Hospital
2012
This study aimed to explore the effects of ubiquitin-specific peptidase 7 (USP7) on acute myocardial infarction (AMI) and negative regulation USP7 by microRNA-409-5p (miR-409-5p). Clinical data were collected from patients admitted Cardiology Department Yan'an Hospital Kunming City between July 2020 2021. The participants included with AMI (AMI; n = 30), stable angina pectoris (SAP; chest pain syndrome (CPS; 30) healthy controls (n 30). expression levels miR-409-5p analysed using...
Although there are a certain number of studies dedicated to the disturbances dopaminergic system induced by traumatic brain injury (TBI), associations abnormal systems with post-traumatic anxiety and depressive disorders their underlying mechanisms have not been clarified yet. In midbrain, neurons mainly situated in substantia nigra (SN) ventral tegmental area (VTA). Thus, we selected SN VTA as regions interest performed seed-based global correlation evaluate altered functional connectivity...
Background: Traumatic brain injury (TBI) often results in persistent cognitive impairment and psychiatric symptoms, while lesion location severity are not consistent with its clinical complaints. Previous studies found deficits disorders following TBI considered to be associated prefrontal medial temporal lobe lesions, however, the extent of contusions cannot fully explain patient′s impairments. Thus, we try find structural changes gray matter (GM) white (WM), clarify their correlation...
Purpose: Necroptosis, a monitored form of inflammatory cell death, contributes to coronary heart disease (CHD) progression. This study examined the potential using necroptosis genes as diagnostic markers for CHD and sought elucidate underlying roles. Methods: Through bioinformatic analysis GSE20680 GSE20681, we first identified differentially expressed (DEGs) related in CHD. Hub were least absolute shrinkage selection operator (LASSO) regression random forest after studying immune...
Our previous study demonstrated that microRNA-409-5p (miR-409-5p) and its target ubiquitin-specific protease 7 (USP7) were involved in hypoxia-induced cardiomyocyte injury ischemic left ventricular remodeling (LVR) rats. This aimed to probe into the relationship between plasma miR-409-5p USP7 levels LVR dysfunction patients with acute myocardial infarction (AMI).
Memory impairment and mood disorders are among the most troubling sequelae following traumatic brain injury (TBI). The relationships between comorbid psychiatric memory function have not been well illustrated. aim of study was to explore anxiety depressive symptoms with TBI.A total 46 TBI participants across all levels 23 healthy controls were enrolled in this case-control study. Wechsler Scale-Chinese Revision (WMS-CR) picture, recognition, associative learning, comprehension memory, digit...
Background. The most prevalent malignant tumor in a human brain nervous system is called glioma. Peptide compound formed by the peptide bond of α-amino acids, and development polypeptide drugs has been widely used many fields. We plan to investigate underlying peptides with clinical value Method. Based on public databases, we targeted common genes between glioma differentially expressed (DEGs) related prognosis. Then, these were analyzed LASSO-Cox analysis, prognostic risk model, nomogram...
Hepatobiliary malignancies, such as hepatocellular carcinoma (HCC) and biliary tract cancers, namely, gallbladder cholangiocarcinoma, are linked to a high rate of morbidity mortality, depending on the phase disease. The intricate hepatobiliary anatomy need for accurate peroperative management, especially in patients with advanced liver disease, make these tumors difficult treat. Surgical resection is notable therapy cancers. Unnecessary or excessive excision influences patient...
Traumatic optic nerve injury is common in patients with traumatic brain injury, mainly young adults. The has no regenerative function, leaving problems of visual field defect and loss vision causing high disability rate among injury. current clinical treatments are hormonotherapy decompression canal, lacking definite efficacy treatment norm. In recent years, a series brand new treatments, such as neuroprotective drugs, neurotrophic factor therapy, transplantation, stem cell therapy gene have...
Cirrhosis is the primary driver of hepatocellular carcinoma (HCC). Blocking deterioration cirrhosis into HCC would be benefit for long–term survival. We applied a series bioinformatic online databases to select and analyze hub genes concerning HCC, identified UBE2T CYP3A4 as cirrhosis-HCC transformation. An elevated decreased were expressed in compared with cirrhosis, which have been confirmed by real-time polymerase chain reaction (RT–PCR), Western Blotting (WB) immunohistochemistry (IHC)....