- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Radiomics and Machine Learning in Medical Imaging
- Tracheal and airway disorders
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Ear and Head Tumors
- Cancer-related molecular mechanisms research
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer-related gene regulation
- Esophageal Cancer Research and Treatment
- Mycobacterium research and diagnosis
- Infective Endocarditis Diagnosis and Management
- Infections and bacterial resistance
- Airway Management and Intubation Techniques
- Streptococcal Infections and Treatments
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Infectious Diseases and Mycology
- Voice and Speech Disorders
- Otolaryngology and Infectious Diseases
- Congenital Diaphragmatic Hernia Studies
University of Alabama at Birmingham
2020-2024
University of California, San Diego
2024
University of Alabama at Birmingham Hospital
2023
Alfred Health
2018
Abstract Purpose: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has continually increased during the past several decades. Using transoral robotic surgery (TORS) significantly improves functional outcomes relative to open for OPSCC. However, TORS limits tactile feedback, which is often most important element cancer surgery. Fluorescence-guided (FGS) strategies aid surgeon assessment malignancy resection are in various phases clinical research but exhibit greatest potential...
A 79-year-old man with liver failure, hypertension and hyperlipidemia presented a 1.5-month history of progressive nasal crusting pain on the inside nose, advancing into necrotic columella philtrum. On rigid endoscopy, debris extended to middle inferior turbinate midway posteriorly. Initial culture swabs CT were negative. The patient underwent endoscopic biopsy lesion, histopathological findings revealing abundant acute inflammation minute fragments atypical squamous epithelium, favouring...
<p>Supplementary Figure S2: Additional characterization of bipolar forceps instrument and normal tissue fluorescence signals without the tumor in view.</p>
<p>Supplementary Video S1: Late-resection intraoperative brightfield and robot fluorescence views of representative OPSCC cases.</p>
<div>AbstractPurpose:<p>The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has continually increased during the past several decades. Using transoral robotic surgery (TORS) significantly improves functional outcomes relative to open for OPSCC. However, TORS limits tactile feedback, which is often most important element cancer surgery. Fluorescence-guided (FGS) strategies aid surgeon assessment malignancy resection are in various phases clinical research but exhibit...
<p>Supplementary Video S2: Locating missed OPSCC fragment using intraoperative robot fluorescence.</p>
<p>Supplementary Figure S1: OPSCC EGFR H-scores.</p>
<p>Supplementary Video S1: Late-resection intraoperative brightfield and robot fluorescence views of representative OPSCC cases.</p>
<p>Supplementary Figure S1: OPSCC EGFR H-scores.</p>
<p>Supplementary Figure S3: Additional characterization of consecutive OPSCC presentations in a single patient.</p>
<div>AbstractPurpose:<p>The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has continually increased during the past several decades. Using transoral robotic surgery (TORS) significantly improves functional outcomes relative to open for OPSCC. However, TORS limits tactile feedback, which is often most important element cancer surgery. Fluorescence-guided (FGS) strategies aid surgeon assessment malignancy resection are in various phases clinical research but exhibit...
<p>Supplementary Figure S2: Additional characterization of bipolar forceps instrument and normal tissue fluorescence signals without the tumor in view.</p>
<p>Supplementary Video S2: Locating missed OPSCC fragment using intraoperative robot fluorescence.</p>
<p>Supplementary Figure S3: Additional characterization of consecutive OPSCC presentations in a single patient.</p>
Context.— Tumor contaminants were incidentally noted in frozen section margins of oropharyngeal squamous cell carcinoma. Objective.— To estimate the frequency tumor slides patients who underwent surgery for pharyngeal cancer, and to characterize surgical pathologic context these incidents. Design.— A retrospective search was conducted identify resections from 2016 2022. Surgical pathology, operative reports, reviewed. Preanalytical phase defined as that occurred with or without occurrence...
Confocal laser endomicroscopy (CLE) represents an emerging probe-based intraoperative optical imaging modality, contingent on differential fluoroscein uptake, equipped to improve identification of subclinical mucosal disease. In the analysis herein, we describe improved sensitivity, compared narrow band and small-volume tissue biopsies, CLE in discrimination occult disease based cellular subcellular morphology during endoscopic resection early-staged larynx cancers. Laryngoscope, 2024.