A5091453343- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Osteoarthritis Treatment and Mechanisms
- Tissue Engineering and Regenerative Medicine
- 3D Printing in Biomedical Research
- Graphene research and applications
- Silk-based biomaterials and applications
- Carbon and Quantum Dots Applications
- Nerve injury and regeneration
- Nanoparticle-Based Drug Delivery
- Polymer Surface Interaction Studies
- Gas Sensing Nanomaterials and Sensors
- Nerve Injury and Rehabilitation
- Advanced Materials and Mechanics
- biodegradable polymer synthesis and properties
- Nanoparticles: synthesis and applications
- Advanced Chemical Sensor Technologies
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Spinal Cord Injury Research
- Advanced Sensor and Energy Harvesting Materials
- Advanced biosensing and bioanalysis techniques
- Transition Metal Oxide Nanomaterials
- Orthopedic Surgery and Rehabilitation
Consejo Superior de Investigaciones Científicas
2020-2025
University of Aveiro
2016-2025
Instituto de Ciencia de Materiales de Madrid
2020-2025
University of Twente
2019-2020
Polycaprolactone (PCL) electrospun scaffolds have been widely investigated for cartilage repair application. However, their hydrophobicity and small pore size has known to prevent cell attachment, proliferation migration. Here, PCL was blended with gelatin (GEL) combining the favorable biological properties of GEL good mechanical performance former. Also, polyethylene glycol (PEG) particles were introduced during electrospinning polymers blend by simultaneous electrospraying. These...
Graphene oxide (GO) assists a diverse set of promising routes to build bioactive neural microenvironments by easily interacting with other biomaterials enhance their bulk features or, alternatively, self-assembling toward the construction biocompatible systems specific three-dimensional (3D) geometries. Herein, we first modulate both size and available oxygen groups in GO nanosheets adjust physicochemical biological properties polycaprolactone–gelatin electrospun nanofibrous systems. The...
The manipulation of the interactions between cationic amine groups from collagen and anionic carboxylic graphene oxide mediate synthesis a self-assembled hydrogel capable generate suitable 3D cellular microenvironments.
Hydrogen energy is a cornerstone of the future climate-neutral economy. Yet, as undetected leaks easily generate dangerous atmospheres, sensing systems must timely detect accumulated hydrogen to prevent ignitions and explosions. Eye-readable sensors (ERSs) displaying intuitive readouts promise guarantee safe use universal access hydrogen-based technology. This review highlights impact reversible ERSs in monitoring contextualize their current potential applicability. First, mechanisms for...
During the past few years, graphene has outstandingly emerged as a key nanomaterial for boosting performance of commercial, industrial and scientific related technologies. The popularity this novel in biomedical engineering is due to its excellent biological, electronic, optical thermal properties that, whole, surpass features commonly used biomaterials consequently open wide range applications so far within reach science fiction. In minireview, potential based materials expanding field...
Abstract One of the established tissue engineering strategies relies on fabrication appropriate materials architectures (scaffolds) that mimic extracellular matrix (ECM) and assist regeneration living tissues. Fibrous structures produced by electrospinning have been widely used as reliable ECM templates but their two‐dimensional structure restricts, in part, cell infiltration proliferation. A recent technique called thermally‐induced self‐agglomeration (TISA) allowed to alleviate this...
A critical challenge in scaffold design for tissue engineering is recapitulating the complex biochemical patterns that regulate cell behavior vivo. In this work, we report adaptation of a standard sterilization methodology – UV irradiation patterning surfaces two complementary polymeric electrospun scaffolds with oxygen cues able to efficiently immobilize biomolecules. Independently different polymer chain length poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT)...
Abstract To recapitulate the heterogeneous complexity of tissues in human body with synthetic mimics extracellular matrix (ECM), it is important to develop methods that can easily allow selective functionalization defined spatial domains. Here, a facile method introduced functionalize microfibrillar meshes different reactive groups able bind biological moieties one‐step reaction. The resulting scaffolds prove selectively support differential neurite growth after being seeded dorsal root...
Abstract To recapitulate the heterogeneous complexity of tissues in our body with synthetic mimics extracellular matrix (ECM), it is important to develop methods that can easily allow selective functionalization defined spatial domains. Here, we introduce a facile method functionalize microfibrillar meshes different reactive groups able bind biological moieties one-step reaction. The resulting scaffolds proved selectively support differential neurite growth after being seeded dorsal root...