A5003733365- Renal cell carcinoma treatment
- Renal and related cancers
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Renal and Vascular Pathologies
- Microfluidic and Bio-sensing Technologies
- Pelvic floor disorders treatments
- Genetic and Kidney Cyst Diseases
- Natural Compounds in Disease Treatment
- Radiomics and Machine Learning in Medical Imaging
- Hormonal Regulation and Hypertension
- Synthesis and Biological Evaluation
- Cancer Genomics and Diagnostics
- Prostate Cancer Treatment and Research
- Cancer, Hypoxia, and Metabolism
- Glutathione Transferases and Polymorphisms
- Urologic and reproductive health conditions
- Adrenal and Paraganglionic Tumors
- Pancreatic and Hepatic Oncology Research
- Bioactive Compounds and Antitumor Agents
Nanjing Drum Tower Hospital
2015-2024
Nanjing University of Chinese Medicine
2023-2024
Nanjing University
2015-2023
Southeast University
2023
Nanjing Medical University
2015
Second Affiliated Hospital of Nanjing Medical University
2014
Abstract Background Phototherapy is a promising strategy for cancer therapy by reactive oxygen species (ROS) of photodynamic (PDT) and hyperthermia photothermal (PTT). However, the therapeutic efficacy was restricted tumor hypoxia thermal resistance increased expression heat shock protein (Hsp). In this study, we developed albumin nanoparticles to combine relief inhibition overcome these limitations phototherapy enhancement. Results Near-infrared photosensitizer (IR780) gambogic acid (GA,...
The role of long non-coding RNA (lncRNA) in the progression renal cell carcinoma (RCC) remains further study. Whether lncRNA may be used to predict immunotherapy efficacy RCC is less studied. In this study, LINC00926 was found mainly located cytoplasm by FISH and nuclear-cytoplasmic fractionation. Downregulation lines inhibited metastasis cells. pull-down assay dual-luciferase reporter demonstrated that functioned as miR-30a-5p sponge facilitate SOX4 expression. overexpression BALB/c mice...
Abstract Background To compare the perioperative outcomes of transperitoneal laparoscopic (TLA), retroperitoneal (RLA), and robot-assisted (RATLA) adrenalectomy for adrenal tumors in our center. Methods Between April 2012 February 2018, 241 minimally invasive adrenalectomies were performed. Cases categorized based on technique. Demographic characteristics, information pathological data retrospectively collected analyzed. Results This study included 37 TLA, 117 RLA, 87 RATLA procedures. Any...
Purpose: To investigate the clinical significance of R.E.N.A.L. nephrometry scoring system in evaluating complications after laparoscopic radiofrequency ablation (LRFA) renal tumors. Patients and Methods: We conducted a retrospective review records all patients who underwent LRFA tumors from February 2006 to March 2012 our institution. Tumors were categorized as low (4–6), moderate (7–9), or high complexity (10–12) according score (NS), which was determined by analyzing preoperative imaging....
Objective To investigate the dynamic contrast-enhanced computed tomography (CT) characteristics of renal cell carcinoma associated with Xp11.2 translocation and TFE gene fusion (Xp11.2 RCC) by comparison clear (CCRCC). Methods Dynamic CT images clinical pathological records 20 adult patients RCC confirmed TFE3 immunohistochemical fluorescence in situ hybridization assay were retrospectively analyzed compared findings 21 contemporary CCRCCs. Results Renal fusions often occurred young (30.6 ±...
To estimate oncologic and functional outcomes for radiofrequency ablation (RFA) versus partial nephrectomy (PN) tumors in a solitary kidney.Nineteen patients with sporadic renal cell carcinoma kidney were treated RFA, 21 PN between November 2008 September 2015. Basic demographic information including age, gender, operative pathological data, complications, function, oncological outcomes, was obtained each patient. Statistical analysis done to test the correlation of clinical features,...
Abstract Background Radical cystectomy (RC) is the standard treatment for bladder cancer, but safety and efficacy of this elderly people need to be considered. We compare perioperative data survival outcomes between (≥80 years) younger (<80 patients undergoing robot-assisted radical (RARC). Methods reviewed demographic, clinical follow-up 190 consecutive with urothelial carcinoma who received RARC from May 2015 December 2018 in Nanjing Drum Tower Hospital. The were divided into 2 groups...
We evaluated percutaneous nephrostomy for adult kidneys with severe hydronephrosis due to ureteropelvic junction obstruction and less than 10% split renal function.In this retrospective analysis we included patients who underwent unilateral of the function at our hospital between May 2009 January 2012. Adults (age 18 years or greater) were divided into those 35 younger (young adults) older (older adults). The remained in situ a mean ± SD 6.62 2.55 weeks repeat renography before pyeloplasty....
<b><i>Objectives:</i></b> To compare the long-term functional and oncological results between laparoscopic radiofrequency ablation (LRFA) partial nephrectomy (LPN) in selected clinical T1a (cT1a) renal tumor patients. <b><i>Methods:</i></b> We retrospectively analyzed medical records of patients with cT1a tumors who had LRFA or LPN at our institution February 2006 2015. Student's t test was used to perioperative data two groups. Survival...
<h2>Abstract</h2><h3>Background</h3> Although partial nephrectomy has become the gold standard for T1 renal tumors whenever technically feasible, simple enucleation shown superior results. To best of our knowledge, no randomized controlled trials comparing these two surgical approaches have been published. <h3>Objective</h3> compare margin status robot-assisted (RASE) and (sRAPN) clinical tumors. <h3>Design, setting, participants</h3> This is a prospective, randomized, controlled,...
We evaluated the safety and efficacy of zero ischemia, radio frequency ablation assisted tumor enucleation for renal cell carcinoma. report incidence complications, positive surgical margins, local recurrence, progression-free disease specific survival rates.We retrospectively reviewed data on 42 patients with carcinoma treated ischemia laparoscopic between March 2006 November 2009. Median age was 60 years (range 37 to 82) 31 (73.8%) were male. The median greatest dimension 3.4 cm 1.8 6.1)....
Abstract This study aimed to compare the clinicopathologic features and prognosis in patients with Xp11 translocation renal cell carcinomas (RCCs). In total, 8083 RCCs were screened at five centres from January 2007 December 2018, including 8001 adults (≥18 years) 82 children (<18 years). Finally, 73 17 identified as RCCs, accounting for 1.1% (90 of 8083) RCCs. However, 4 1 adult excluded because loss follow-up when performing survival analysis. The proportion paediatric was 20.7% (17 82)...
Abstract Purpose To evaluate the oncologic efficacy and feasibility of nephron-sparing surgery (NSS) in adult Xp11.2 translocation renal cell carcinoma (RCC). Patients Methods Seventy patients with RCC 273 conventional from five institutions Nanjing were retrospectively studied. All older than 18 years categorized into clinical T1 (cT1) stage using preoperative imaging. Using imaging electronic medical records, anatomical pathological features collected analyzed. Results Among RCC, 18/36...
To analyze changes in renal function and associated risk factors patients with bladder cancer undergoing robot-assisted radical cystectomy (RARC) intracorporeal or extracorporeal urinary diversion (ICUD ECUD).
To assess the functional and oncologic outcomes of laparoscopic radiofrequency ablation (RFA) with intraoperative contrast-enhanced ultrasonography in treatment T1b renal tumors.We performed a retrospective review 51 patients unilateral tumors who underwent RFA from January 2007 to April 2012 mean follow-up 31.5 months. The were laparoscopically dissected ablated cool-tip system under guidance ultrasound. Routine included computed tomography/magnetic resonance imaging (CT/MRI) function...