A5073355835- Aquaculture disease management and microbiota
- Immune Response and Inflammation
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Analytical Chemistry and Sensors
- Immune Cell Function and Interaction
- Invertebrate Immune Response Mechanisms
- Physiological and biochemical adaptations
- Inflammatory mediators and NSAID effects
- Vitamin C and Antioxidants Research
- Bone Metabolism and Diseases
- NF-κB Signaling Pathways
- RNA and protein synthesis mechanisms
- TGF-β signaling in diseases
- Cancer, Lipids, and Metabolism
- Electromagnetic Fields and Biological Effects
- Genomics and Phylogenetic Studies
- Analytical Methods in Pharmaceuticals
- stochastic dynamics and bifurcation
- Immune cells in cancer
- Aquaculture Nutrition and Growth
- MicroRNA in disease regulation
- Vitamin D Research Studies
- Antioxidant Activity and Oxidative Stress
- Psoriasis: Treatment and Pathogenesis
University of Electronic Science and Technology of China
2015-2024
Moffitt Cancer Center
2012-2019
Department of Embryology
2012
Carnegie Institution for Science
2012
National Jewish Health
2012
University of Colorado Denver
2012
The successful prediction of protein subcellular localization directly from primary sequence is useful to function and drug discovery. In this paper, by using the concept pseudo amino acid composition (PseAAC), mycobacterial proteins are studied predicted support vector machine (SVM) increment diversity combined with modified Mahalanobis Discriminant (IDQD). results jackknife cross-validation for 450 nonredundant show that overall rates SVM IDQD 82.2% 79.1%, respectively. Compared other...
Vitamin E δ-tocotrienol has been shown to have antitumor activity, but the precise molecular mechanism by which it inhibits proliferation of cancer cells remains unclear. Here, we demonstrated that exerted significant cell growth inhibition pancreatic ductal (PDCA) without affecting normal human epithelial growth. We also showed δ-tocotrienol-induced occurred concomitantly with G1 cell-cycle arrest and increased p27Kip1 nuclear accumulation. This finding is considering loss expression a...
Although more and entangled participants of translation process were realized, how they cooperate co-determine the final efficiency still lacks details. Here, we reasoned that basic components, tRNAs amino acids should be consistent to maximize minimize cost. We firstly revealed 310 out 410 investigated genomes three domains had significant co-adaptions between tRNA gene copy numbers acid compositions, indicating maximum constitutes ubiquitous selection pressure on protein translation....
In fish immunity, the regulatory role of transforming growth factor-β1 (TGF-β1) has not been fully characterized. Here we examined immunoregulatory effects TGF-β1 in grass carp peripheral blood leukocytes (PBL) and head kidney (HKL). It is interesting that consistently stimulated cell viability mRNA levels pro-inflammatory cytokines (Tnfα Ifnγ) T/B markers [Cd4-like (Cd4l), Cd8α, Cd8β Igμ] PBL, which contrasted with its inhibitory tone HKL. Further studies showed type I receptor, activin...