A5081795344- Zoonotic diseases and public health
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Viral Infections and Outbreaks Research
- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Antibiotic Use and Resistance
- Vaccine Coverage and Hesitancy
- Virology and Viral Diseases
- Pharmaceutical and Antibiotic Environmental Impacts
- Data-Driven Disease Surveillance
- Mosquito-borne diseases and control
- Aquaculture disease management and microbiota
- Global Maternal and Child Health
- COVID-19 epidemiological studies
- Viral Infections and Immunology Research
- Diagnosis and treatment of tuberculosis
- Animal Virus Infections Studies
- Salmonella and Campylobacter epidemiology
- Public Health Policies and Education
- Veterinary Practice and Education Studies
- Livestock and Poultry Management
- Vibrio bacteria research studies
Southern African Centre for Infectious Disease Surveillance
2012-2022
Sokoine University of Agriculture
2013-2022
Woking Community Hospital
2006
United Nations
2000
We describe the development and initial achievements of a participatory disease surveillance system that relies on mobile technology to promote Community Level One Health Security (CLOHS) in Africa.The objective this system, Enhancing Community-Based Disease Outbreak Detection Response East Southern Africa (DODRES), is empower community-based human animal health reporters with training information communication (ICT)-based solutions contribute detection response, thereby complementing...
The increased presence of extended-spectrum beta-lactamase (ESBL)-producing bacteria in humans, animals, and their surrounding environments is global concern. Currently there limited information on ESBL rural farming communities worldwide. We performed a cross-sectional study Mwanza, Tanzania, involving 600 companion domestic farm animals between August/September 2014. Rectal swab/cloaca specimens were processed to identify ESBL-producing Enterobacteriaceae. detected 130 (21.7%) carrying...
Abstract Background Antimicrobial resistance (AMR) represents one of the biggest threats to health globally. This cross-sectional study determined knowledge, attitudes and practices (KAP) regarding antimicrobial use (AMU) AMR among communities Ilala, Kilosa Kibaha in Tanzania. Method A semi-structured questionnaire was used collect socio-demographic KAP data through face-to-face interviews. Responses related triad were assigned scores that aggregated for each participant. Linear regression...
Tanzania launched its first National Action Plan (NAP) on antimicrobial resistance (AMR) in 2017 to reduce the burden of AMR country and contribute global response. We aimed analyze implementation NAP using governance framework. In-depth interviews were conducted with human animal health practitioners national-level policy actors. adapted Chua's framework development Tanzania. Implementation has realized several achievements, including: (i) establishment a functioning Multi-Sectoral...
Zoonoses account for the most commonly reported emerging and re-emerging infectious diseases in Sub-Saharan Africa. However, there is limited knowledge on how pastoral communities perceive zoonoses relation to their livelihoods, culture wider ecology. This study was carried out explore local perceptions among pastoralists Tanzania.This involved Ngorongoro district northern Tanzania Kibaha Bagamoyo districts eastern Tanzania. Qualitative methods of focus group discussions, participatory...
Abstract Background Tuberculosis (TB), particularly multi- and or extensive drug resistant TB, is still a global medical emergency. Whole genome sequencing (WGS) current alternative to the WHO-approved probe-based methods for TB diagnosis detection of resistance, genetic diversity transmission dynamics Mycobacterium tuberculosis complex (MTBC). This study compared WGS clinical data in participants with TB. Results cohort performed on 87 from MTBC DNA isolates, 57 (66%) 30 (34%) patients...
Uncontrolled use of drugs both in humans and animals coupled with environmental contamination exacerbate the development spread antimicrobial resistance. This paper assessed drivers resistance poultry domestic pig farming environment. Questionnaires, in-depth interviews, focus group discussions (FGDs) were used to collect information regarding demographic characteristics, knowledge, practices, attitudes, perceptions animal We found a higher proportion usage veterinary antimicrobials for...
A paper-based disease reporting system has been associated with a number of challenges. These include difficulties to submit hard copies the surveillance forms because poor road infrastructure, weather conditions or challenging terrain, particularly in developing countries. The demands re-entry data at processing and analysis points, thus making it prone introduction errors during this process. All these challenges contribute delayed acquisition, response events occurring remote reach areas....
Non-tuberculous mycobacteria (NTM), which are ubiquitous micro-organisms occurring in humans, animals and the environment, sometimes receive public health veterinary attention as opportunistic disease-causing agents. In Tanzania, there is limited information regarding diversity of NTM species, particularly at human-livestock-wildlife interface such Serengeti ecosystem, where potential for cross species infection or transmission may exist. Mycobacterial DNA was extracted from cultured...
The aim of this study was to assess and characterize Mycobacterium tuberculosis complex (MTBC) genotypic diversity in Tanzania, as well neighbouring East other several African countries. We used spoligotyping identify a total 293 M. clinical isolates (one isolate per patient) collected the Bunda, Dar es Salaam, Ngorongoro Serengeti areas Tanzania. results were compared with SITVIT2 international database Pasteur Institute Guadeloupe. Genotyping phylogeographical analyses highlighted...
Background: This study was conducted to determine the seroprevalence and risk factors of chikungunya (CHIKV), dengue (DENV), Zika (ZIKV) viruses in Tanzania.Methods: The covered districts Buhigwe, Kalambo, Kilindi, Kinondoni, Kondoa, Kyela, Mvomero, Ukerewe Tanzania. Blood samples were collected from individuals recruited households healthcare facilities. An ELISA used screen for immunoglobulin G antibodies against CHIKV, DENV, ZIKV.Results: A total 1818 participants (median age 34 years)...
Rift Valley fever (RVF) is an acute arthropod-borne viral zoonotic disease primarily occurring in Africa. Since RVF-like was reported Tanzania 1930, outbreaks of the have been mainly from eastern ecosystem Great Valley. This cross-sectional study carried out to describe variation RVF virus (RVFV) seropositivity domestic ruminants between selected villages and western ecosystems Tanzania, identify potential risk factors. Three were purposively each two ecosystems. Serum samples randomly (n =...
Africa has the highest burden of infectious diseases in world and yet least capacity for its risk management. It therefore become increasingly important to search ‘fit-for- purpose’ approaches disease surveillance thereby targeted control. The fact that majority human are originally animal origin means we have consider One Health (OH) which require inter-sectoral collaboration custom-made endemic settings Africa. A baseline survey was conducted assess current status performance health...
Mycobacterium bovis, the causative agent of bovine tuberculosis (bTB), is a multihost pathogen public health and veterinary importance. We characterized M. bovis isolated at human-livestock-wildlife interface Serengeti ecosystem to determine epidemiology risk cross-species transmission between interacting hosts species. DNA was extracted from mycobacterial cultures obtained sputum samples 472 (TB) suspected patients tissue 606 livestock wild animal isolates were using spoligotyping...
There is increasing policy demand for real-time evaluations of research and capacity-building programmes reflecting a recognition the management, governance impact gains that can result. However, evidence base on how to successfully implement complex interventions in international development efforts scarce. therefore need reflective work considers methodologies context. This article shares learning from experience conducting participatory, real-time, ‘theory driven’ evaluation African...
This study was part of a larger cross-sectional survey that evaluating tuberculosis (TB) infection in humans, livestock and wildlife the Serengeti ecosystem Tanzania. The aimed at genetic diversity Mycobacterium isolates from TB patients attending health facilities ecosystem. DNA extracted 214 sputum cultures obtained consecutively enrolled newly diagnosed untreated aged ≥18 years. Spacer oligonucleotide typing (spoligotyping) Interspersed Repetitive Units Variable Number Tandem Repeat...
The rise in the spread of antibiotic-resistant pathogens such as Escherichia coli is one very important dynamics off-putting treatment and prophylaxis possibilities, hence posing a threat to modern human medicine, veterinary food safety. Therefore, aim this study was determine antimicrobial resistance profiles E. isolates obtained from broiler layer chickens Mwanza Arusha regions Tanzania. A cross-sectional carried out February March, 2021, 402 poultry farms (201) All samples that tested...