A5071048141- Topic Modeling
- Natural Language Processing Techniques
- Advanced Graph Neural Networks
- Semiconductor materials and devices
- Text Readability and Simplification
- Semiconductor Quantum Structures and Devices
- Antibiotic Resistance in Bacteria
- Domain Adaptation and Few-Shot Learning
- Radio Frequency Integrated Circuit Design
- Drug Transport and Resistance Mechanisms
- Antimicrobial Peptides and Activities
- Complex Network Analysis Techniques
- GaN-based semiconductor devices and materials
- Advancements in Semiconductor Devices and Circuit Design
- Reproductive Biology and Fertility
- Antimicrobial Resistance in Staphylococcus
- Bacterial Genetics and Biotechnology
- Superconducting Materials and Applications
- Speech and dialogue systems
- Multimodal Machine Learning Applications
- Bayesian Modeling and Causal Inference
- Handwritten Text Recognition Techniques
- Biochemical and Structural Characterization
- Botanical Research and Chemistry
- Text and Document Classification Technologies
National Institute of Health Sciences
2024
National Institute of Health Sciences
2019-2024
Osaka University
2013-2023
Gunma University
2021
The University of Tokyo
2020
RIKEN Center for Advanced Intelligence Project
2019
Tokyo Institute of Technology
2018
NTT (Japan)
2015-2018
Osaka Research Institute of Industrial Science and Technology
2014-2017
Kyoto Seika University
2017
We show the equivalence of two state-of-the-art models for link prediction/knowledge graph completion: Nickel et al's holographic embeddings and Trouillon al.'s complex embeddings. first consider a spectral version embeddings, exploiting frequency domain in Fourier transform efficient computation. The analysis resulting model reveals that it can be viewed as an instance with certain constraint imposed on initial vectors upon training. Conversely, any set converted to equivalent
In recent years, there has been a notable increase in research on machine learning models for music retrieval and generation systems that are capable of taking natural language sentences as inputs. However, is scarcity large-scale publicly available datasets, consisting data their corresponding descriptions known captions. particular, non-musical information such suitable situations listening to track the emotions elicited upon crucial describing music. This type underrepresented existing...
Extreme multi-label learning (XML) is a task of assigning multiple labels from an extremely large set to each data instance. Many current high-performance XML models are composed lot hyperparameters, which complicates the tuning process. Additionally, themselves adapted specifically XML, their reimplementation. To remedy this problem, we propose simple method based on ridge regression for XML. The proposed not only has closed-form solution but also single hyperparameter. Since there no...
ABSTRACT The AcrAB-TolC system in Escherichia coli is an intrinsic RND-type multidrug efflux transporter that functions as a tripartite complex of the inner membrane AcrB, outer channel TolC, and adaptor protein AcrA. Although crystal structures each component this have been elucidated, structure whole has not solved. available shown AcrB TolC function trimers, but number AcrA molecules now under debate. Disulfide chemical cross-linking experiments indicated stoichiometry AcrB-AcrA-TolC...
Two heuristic rules that transform Rhetorical Structure Theory discourse trees into dependency (DDTs) have recently been proposed (Hirao et al., 2013;Li 2014), but these derive significantly different DDTs because their conversion schemes on multinuclear relations are not identical.This paper reveals the difference among DDT formats with respect to following questions:(1) How complex from a graph theoretic point of view?(2) Which analyzed more accurately by automatic parsers?(3) suitable for...
Honey has a complex chemistry, and its broad-spectrum antimicrobial activity varies with floral source, climate, harvesting conditions. Methylglyoxal was identified as the dominant antibacterial component of manuka honey. Although it been known that methylglyoxal against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus vancomycin-resistant Enterococcus, there is not much information describing gram-negative bacteria. In this study, we report effect...
The most common diagnostic method used for coronavirus disease-2019 (COVID-19) is real-time reverse transcription polymerase chain reaction (PCR). However, it requires complex and labor-intensive procedures involves excessive positive results derived from viral debris. We developed a the direct detection of severe acute respiratory syndrome 2 (SARS-CoV-2) in nasopharyngeal swabs, which uses matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-ToF MS) to...
Genes vmeA and vmeB, encoding a multidrug efflux transporter in the halophilic bacterium Vibrio parahaemolyticus, have been cloned using drug-hypersusceptible Escherichia coli strain as host. Cells of E. KAM33 (DeltaacrAB DeltaydhE) carrying vmeAB region from V. parahaemolyticus conferred much higher MICs for variety antimicrobial agents than did control cells. possessing VmeAB under energized conditions maintained very low intracellular concentrations ethidium. This was expected an...
We show the equivalence of two state-of-the-art link prediction/knowledge graph completion methods: Nickel et al's holographic embedding and Trouillon al.'s complex embedding. first consider a spectral version embedding, exploiting frequency domain in Fourier transform for efficient computation. The analysis resulting method reveals that it can be viewed as an instance with certain constraints cast on initial vectors upon training. Conversely, any converted to equivalent
Hidetaka Kamigaito, Katsuhiko Hayashi, Tsutomu Hirao, Masaaki Nagata. Proceedings of the 2018 Conference North American Chapter Association for Computational Linguistics: Human Language Technologies, Volume 1 (Long Papers). 2018.
Magainin 2 (Mag 2), which is isolated from the skin of frogs, a representative antimicrobial peptide (AMP), exerts its activity via microbial membrane disruption. It has been reported that both amphipathicity and helical structure Mag play an important role in activity. In this study, we revealed sequence 17 amino acid residues (peptide 7) required to exert sufficient We also designed set derivatives, based on enhancement helicity and/or amphipathicity, by incorporation α,α-disubstituted...
Sho Hoshino, Yusuke Miyao, Katsuhito Sudoh, Katsuhiko Hayashi, Masaaki Nagata. Proceedings of the 53rd Annual Meeting Association for Computational Linguistics and 7th International Joint Conference on Natural Language Processing (Volume 2: Short Papers). 2015.
This paper proposes a discriminative forest reranking algorithm for dependency parsing that can be seen as form of efficient stacked parsing. A dynamic programming shift-reduce parser produces packed derivation which is then scored by reranker, using the 1-best tree output guide features in addition to third-order graph-based features. To improve efficiency and accuracy, this also novel eliminates spurious ambiguity arc-standard transition systems. Testing on English Penn Treebank data, gave...
A large number of drug efflux transporters have been identified in Salmonella enterica serovar Typhimurium, and increased expression these confers resistance this organism. Here we compared the respiration activities wild-type strain a mutant with nine deleted by phenotype microarray analysis. The was susceptible to 66 structurally unrelated compounds including many antibiotics, dyes, detergents, antihistamine agents, plant alkaloids, antidepressants, antipsychotic drugs, antiprotozoal...
Abstract Aerosols or saliva containing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can contaminate living environments, and viruses be indirectly transmitted. To understand the survival potential of virus, viral titers bovine (BCoV), as a model SARS-CoV-2 were measured on porous non-porous surfaces. The amount infectious BCoV recovered remained relatively high substrates. However, it quickly decreased several surfaces such nitrile rubber. time taken to reach limit detection...
We have been developing the UPS-SMES as a protection from momentary voltage drop and power failure. The superconducting system is suitable electric storage for large energy extraction in short time. most important feature of coil easy handling maintenance-free operation. selected low temperature (LTS) coils instead high (HTS) viewpoint cost performance. However, it difficult conventional LTS to fulfill operation since cooling methods are either pool boiling with liquid helium or forced flow...
The overexpression of RND-type exporters is one the main causes multidrug resistance (MDR) in Gram-negative pathogens. In RND transporters, such as Escherichia coli's efflux pump AcrB, drug occurs porter domain, while protons flow through transmembrane domain: remote conformational coupling. At border a helix (TM8) and subdomain PC2, there loop which makes hoisting movement by random-coil-to-α-helix change, opens closes channel entrance. This supposed to play key role allosteric coupling...