We report a novel example of electro-mediated photoredox catalysis (e-PRC) in the reductive cleavage C(sp

We analyze how the photorelaxation dynamics of a molecule can be controlled by modifying its electromagnetic environment using nanocavity mode. In particular, we consider RNA nucleobase uracil, which is natural mechanism to prevent photodamage. our theoretical work, identify operative conditions in strong coupling with cavity mode open an efficient photoprotective channel, resulting relaxation twice as fast one. rely on state-of-the-art chemically detailed molecular model and non-Hermitian...

Optical metasurfaces enable the manipulation of light–matter interaction in ultrathin layers. Compared with their metal or dielectric counterparts, hybrid resulting from combination and metallic nanostructures can offer increased possibilities for interactions between modes present system. Here, we investigate lattice resonances a metal–dielectric metasurface obtained single-step nanofabrication process. Finite-difference time domain simulations show avoided crossing appearing...

Tumor lysis syndrome (TLS) is a complication that can cause renal failure by precipitation of uric acid (UA) and phosphate crystals in tubules. Rasburicase proved to be effective rapidly reducing UA levels. Costs rasburicase average up 4500 euros. To assess if lower doses are effective, we treated patients with than recommended.Fifty received for prophylaxis (n = 8) or treatment 42) TLS. The median age was 67 yr (16-88), 21 were female. majority 46) had hematologic malignancies (acute...

Cyanobacterial photosystem I (PSI) is one of the most efficient photosynthetic machineries found in nature. Due to large scale and complexity system, energy transfer mechanism from antenna complex reaction center still not fully understood. A central element accurate evaluation individual chlorophyll excitation energies (site energies). Such an must include a detailed treatment site specific environmental influences on structural electrostatic properties, but also their evolution temporal...

Abstract Pyrene is a prime example of molecules that form dimers in the excited state. These excimers give rise to highly distinguishable, red‐shifted emission band which major importance applications such as bio‐labeling, light‐harvesting or organic sensors. Understanding this excimer fluorescence on molecular level therefore crucial importance. We systematically investigate state conformations pyrene dimers, using quantum chemical calculations and geometry optimizations. Furthermore, we...

Abstract We report a novel example of electro‐mediated photoredox catalysis (e‐PRC) in the reductive cleavage C(sp 3 )−O bonds phosphinated alcohols to alkyl carbanions. As well as deoxygenations, olefinations are reported which E ‐selective and can be made Z tandem reduction/photosensitization process where both steps photoelectrochemically promoted. Spectroscopy, computation, catalyst structural variations reveal that our new naphthalene monoimide‐type allows for an intimate dispersive...

Titanium nitride (TiN) is a complementary metal-oxide-semiconductor (CMOS) compatible material with large potential for the fabrication of plasmonic structures suited device integration. However, comparatively optical losses can be detrimental application. This work reports CMOS TiN nanohole array (NHA) on top multilayer stack use in integrated refractive index sensing high sensitivities at wavelengths between 800 and 1500 nm. The stack, consisting NHA silicon dioxide (SiO2) layer Si as...

Abstract: Introduction : Rasburicase is a recombinant urate oxidase that produced by genetically modified Saccharomyces cerevisiae and has been approved for prophylaxis treatment of tumor lysis syndrome in 2001. In several studies, rasburicase, given at dose 0.15–0.2 mg/kg up to 7 d, proved be highly effective lowering levels. Case report We the case patient with chronic lymphatic leukemia (CLL) who experienced (TLS) acute renal failure after fludarabine/cyclophosphamide chemotherapy...

UV light can induce chemical reactions in nucleic acids and thereby damage the genetic code. Like all of five primary nucleobases, isolated RNA base uracil exhibits ultrafast, nonradiative relaxation after photoexcitation, which helps to avoid photodamage most time. Nevertheless, within DNA strands, commonly occurring photolesions have been reported are often ascribed long-lived delocalized excited states. Our quantum dynamical study now shows that excited-state longevity also occur on a...

The ultrafast relaxation within the Q-bands of chlorophyll plays a crucial role in photosynthetic light-harvesting. Yet, despite being focus many experimental and theoretical studies, it is still not fully understood. In this paper we look at process from perspective non-adiabatic wave packet dynamics. For purpose, identify vibrational degrees freedom which contribute most to coupling. Using selection normal modes, construct four reduced-dimensional coordinate spaces investigate dynamics on...

We report electrical spin injection and detection in degenerately doped n-type Ge channels using Mn5Ge3C0.8/Al2O3/n^{+}-Ge tunneling contacts for detection. The whole structure is integrated on a Si wafer complementary metal-oxide-semiconductor compatibility. From three-terminal Hanle-effect measurements, we observe accumulation up to 10 K. lifetime extracted be 38 ps at T = 4K Lorentzian fitting, the diffusion length estimated 367 nm due high coefficient of highly channel.

Electrocatalytic hydrogen production via transition metal complexes offers a promising approach for chemical energy storage. Optimal platforms to effectively control the proton and electron transfer steps en route H2 evolution still need be established, redox-active ligands could play an important role in this context. In study, we explore of Mabiq (Mabiq = 2–4:6–8-bis(3,3,4,4-tetramethlyldihydropyrrolo)-10–15-(2,2-biquinazolino)-[15]-1,3,5,8,10,14-hexaene1,3,7,9,11,14-N6) ligand reaction...

Research Article| May 01 1982 Formation and degradation of deoxyadenosine nucleotides in inherited adenosine deaminase deficiency H. A. Simmonds; Simmonds *Purine Laboratory, Guy's Hospital, London, SE1 9RT, U.K. Search for other works by this author on: This Site PubMed Google Scholar D. R. Webster; Webster Perrett; Perrett **Medical Unit, St. Bartholomew's EC1A 7BE, S. Reiter; Reiter J. Levinsky †Department Immunology, Institute Child Health, WC1N 1EH, Biosci Rep (1982) 2 (5): 303–314....

Abstract Precious metal complexes remain ubiquitous in photoredox catalysis (PRC) despite concerted efforts to find more earth‐abundant catalysts and replacements based on 3d metals particular. Most otherwise plausible are assumed be unsuitable due short‐lived excited states, which has led researchers prioritize the pursuit of longer excited‐state lifetimes through careful molecular design. However, we report herein that C−H arylation pyrroles related substrates (which benchmark reactions...