A5101435410- RNA modifications and cancer
- Cancer-related gene regulation
- Cancer-related molecular mechanisms research
- Computational Drug Discovery Methods
- Anesthesia and Neurotoxicity Research
- Signaling Pathways in Disease
- Metabolomics and Mass Spectrometry Studies
- Endoplasmic Reticulum Stress and Disease
- Toxin Mechanisms and Immunotoxins
- Synthesis of Tetrazole Derivatives
- Synthesis and biological activity
- Traumatic Brain Injury and Neurovascular Disturbances
- Receptor Mechanisms and Signaling
- Galectins and Cancer Biology
- Cardiac Ischemia and Reperfusion
- Liver Disease and Transplantation
- Maternal Mental Health During Pregnancy and Postpartum
- Immune Response and Inflammation
- Metabolism and Genetic Disorders
- Neuroendocrine regulation and behavior
- Tryptophan and brain disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Peptidase Inhibition and Analysis
- Cancer Mechanisms and Therapy
- Genetics and Neurodevelopmental Disorders
The First Affiliated Hospital, Sun Yat-sen University
2021
Sun Yat-sen University
2021
Southern Medical University
2015-2018
Xiangya Hospital Central South University
2009
Central South University
2006-2009
Abstract Serine/arginine-rich splicing factor 7 (SRSF7), a known factor, has been revealed to play oncogenic roles in multiple cancers. However, the mechanisms underlying its have not well addressed. Here, based on N 6-methyladenosine (m 6 A) co-methylation network analysis across diverse cell lines, we find that gene expression of SRSF7 is positively correlated with glioblastoma (GBM) cell-specific m6A methylation. We then indicate novel regulator, which specifically facilitates methylation...
To determine the pathological mechanism and prevent heart-renal syndrome after heart valve replacement surgery.A total of 46 patients were admitted for selective replacement, divide into 3 groups randomly: a control group (Con, n=16), remote ischemic perconditioning (RIPerC) (n=15) postconditioning (RIPostC) (n=15). The serum creatinine (SCr), blood urea nitrogen (BUN), heme oxygennase-1 (HO-1), iron urinary neutrophil gelatinase associated lipocalin (NGAL) level in compared preoperatively...
Phosphorylation of proteins on serine or threonine residues preceding proline is a major regulatory mechanism in cell proliferation and transformation, which catalyzed specifically by Pin1, peptidylprolyl isomerase. Pin1 overexpressed several human cancers. The expression mRNA the circulation was assessed 26 patients with non-small-cell lung cancer who underwent surgical resection. They were randomly assigned to pulmonary artery first ligation group vein group. blood samples from cancer,...
To explore the protective effect of noninvasive limb ischemic preconditioning (N-LIP) on acute lung injury (ALT) induced by lipopolysaccharide (LPS) in rats.Fifteen female SD rats were randomly divided into a control group, an group (ALI group), and (ALI+N-LIP group). After ALI treated with N-LIP, changes airway resistance (AR) dynamic compliance (Cdyn) tested invasive pulmonary function system recorded. Blood samples bronchoalveolar lavage fluid (BALF) collected, amounts white blood cell...
Abstract Serine/Arginine-Rich Splicing Factor 7 (SRSF7), which is previously recognized as a splicing factor, has been revealed to play oncogenic roles in multiple cancers. However, the mechanisms underlying its have not well addressed. Here, based on N6-methyladenosine (m 6 A) co-methylation network analysis across diverse cell lines, we found SRSF7 positively correlated with glioblastoma cell-specific m A methylation. We then proved novel regulator that specifically facilitates methylation...