- Electroconvulsive Therapy Studies
- Bipolar Disorder and Treatment
- Autoimmune Neurological Disorders and Treatments
- Schizophrenia research and treatment
- Electrolyte and hormonal disorders
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Child Abuse and Trauma
- Genetics and Neurodevelopmental Disorders
- Obsessive-Compulsive Spectrum Disorders
- Neuroscience and Neuropharmacology Research
- Child and Adolescent Psychosocial and Emotional Development
- Maternal Mental Health During Pregnancy and Postpartum
- Child Nutrition and Feeding Issues
- Attention Deficit Hyperactivity Disorder
- Treatment of Major Depression
- Homicide, Infanticide, and Child Abuse
- Psychiatric care and mental health services
- Autism Spectrum Disorder Research
- Polyomavirus and related diseases
- Coordination Chemistry and Organometallics
- Peripheral Neuropathies and Disorders
- Psychosomatic Disorders and Their Treatments
- Advanced MRI Techniques and Applications
- Pharmaceutical studies and practices
Assistance Publique – Hôpitaux de Paris
2012-2023
Sorbonne Université
2012-2023
Pitié-Salpêtrière Hospital
2012-2023
Troubles psychiatriques et développement
2017-2022
King's College London
2008-2016
Sorbonne Paris Cité
2016
Kings Health Partners
2010
South London and Maudsley NHS Foundation Trust
2008
Abstract Prader–Willi Syndrome (PWS) is a rare genetic syndrome leading to severe behavioural disorders and mild cognitive impairment. The objective of this double-blind randomised placebo-controlled trial was study the efficacy tolerance topiramate on in patients with PWS. Participants (aged 12–45 years) had genetically confirmed PWS irritability/impulsivity, eating and/or obesity, skin picking. Thirty-two participants received placebo (PBO), 30 (TOP) (50–200 mg/day) for 8 weeks. primary...
The identification of individuals at high risk developing psychosis is entirely based on clinical assessment, associated with limited predictive potential. There therefore increasing interest in the development biological markers that could be used practice for this purpose. We studied 25 an At Risk Mental State and healthy controls using structural MRI, functional MRI conjunction a verbal memory task. Data were analysed standard univariate analysis, Support Vector Machine (SVM),...
BackgroundThere is no consensus as to whether magnetic resonance imaging (MRI) should be used part of the initial clinical evaluation patients with first-episode psychosis (FEP).Aims(a) To assess logistical feasibility routine MRI; (b) define significance radiological abnormalities in FEP.MethodRadiological reports from MRI scans two FEP samples were reviewed; one comprised 108 and 98 healthy controls recruited a research study other 241 scanned at presentation plus 66 controls.ResultsIn...
Catatonia as a result of autoimmune conditions offers new therapeutic opportunities for patients that child and adolescent psychiatrists should consider. However, the diagnosis is sometimes challenging when an signature not identified.In this study, we aim to summarize seven cases from 20-year series 84 youths with catatonia, including three represented diagnostic challenge because absence positive testing.Immunosuppressive/modulatory treatment improved catatonic psychotic features in all...
Objectives: Osteoporosis is a major risk factor for fracture and treatment mainly preventive. Patients with severe psychiatric condition treated antipsychotics are at vitamin D deficiency iatrogenic hyperprolactinemia, two serious factors of osteoporosis. We aim to determine whether all similar regarding the osteoporosis in young patients. Methods: From January 2009 March 2015, we determined blood level (VDBL) among 484 inpatients from 2012 prolactin (PBL) 205 inpatients. systematically...
Psychotic disorders in children are more heterogeneous than is captured by categorical diagnoses. In a new cohort of and adolescents, we evaluated the relationships among age at onset (AAO), clinical symptoms developmental impairments. Patients with schizophrenia other "spectrum" psychotic diagnoses (N = 88; AAO 6–17, mean 12.6) were diagnostic interviews, scale (Lifetime Dimensions Psychosis Scale-Child Adolescent), neuropsychological medical evaluations. Key findings replicated an adult...