A5112340178- Advanced Welding Techniques Analysis
- Welding Techniques and Residual Stresses
- Aluminum Alloy Microstructure Properties
- Microstructure and mechanical properties
- Metal Forming Simulation Techniques
- Advanced Machining and Optimization Techniques
- Aluminum Alloys Composites Properties
- Liver physiology and pathology
- Fatigue and fracture mechanics
- Advanced Surface Polishing Techniques
- High-Velocity Impact and Material Behavior
- Organ Transplantation Techniques and Outcomes
- Immune Cell Function and Interaction
- Macrophage Migration Inhibitory Factor
- Additive Manufacturing Materials and Processes
- Erosion and Abrasive Machining
- Laser and Thermal Forming Techniques
- Thermal Analysis in Power Transmission
- Non-Destructive Testing Techniques
- MicroRNA in disease regulation
- Immune cells in cancer
- Microstructure and Mechanical Properties of Steels
- Laser Material Processing Techniques
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
Anhui Medical University
2022-2025
Commercial Aircraft Corporation of China (China)
2016-2021
Ningbo University
2021
Southwest Jiaotong University
2018
Abstract Colorectal cancer (CRC) usually creates an immunosuppressive microenvironment, thereby hindering immunotherapy response. Effective treatment options remain elusive. Using scRNA‐seq analysis in a tumor‐bearing murine model, it is found that lobeline, alkaloid from the herbal medicine lobelia, promotes polarization of tumor‐associated macrophages (TAMs) toward M1‐like TAMs while inhibiting their M2‐like TAMs. Additionally, lobeline upregulates mRNA expression secreted...
A novel approach to welding crack sensitive 2024 aluminium alloy was made by using fibre laser. Bead on plate of 3 mm thick sheets 2024-T3 performed determine the optimum sets parameters including laser power, speed, power density and focal position, which meet quality specification requirements aircraft structures. correlation between these weld shape, microstructure, defects found. The assessed in terms weld-seam geometry, root width ratio, surface appearance, penetration depth,...
This paper presents an experimental and numerical study of residual stress states deformation in fillet welded AA2024-T3 T-joints produced using a high-power fibre laser. Welded sheets with one three stiffeners were prepared, respectively, to determine changes microstructure, stress, distortion micro-hardness. 3D sequentially coupled thermo-mechanical finite element models developed analyse welding temperature fields, accurately simulate stresses deformation. The simulated results calibrated...
Aluminium–lithium (Al-Li) alloys are very attractive for aerospace applications due to their outstanding properties, such as high specific strength, rigidity and good resistance corrosion fatigue, compared conventional aluminium alloys. The butt joints of Al-Li 2A97-T3 alloy sheet produced by fibre laser welding with ER2319 filler wire were investigated in this paper. Uniaxial tensile tests have been performed determine the nominal mechanical properties without porosities. In addition, a...
Abstract A new perspective of damage‐induced shear strain localization is proposed to elucidate the formation mechanism fine granular area (FGA) generated in a high‐strength steel under very‐high‐cycle fatigue (VHCF). The development local strain, effective resolved stress, and damage evolution at vicinity an inclusion has been predicted by crystal plasticity finite element method (CPFEM) coupled with stress ratios R = −1, 0.1, 0.5. microstructure FGA characterized using scanning electron...
Good quality 1.2-mm-thick 2A97 Al–Li alloy butt joints were achieved by the fiber laser welding with filler ER5356. Thorough investigations then performed on microstructure, porosity size and location, softening behavior, tensile strength fatigue limit, together failure mechanism via third-generation synchrotron X-ray microtomography. Results show that very narrow EQuiaxed Zone (EQZ) inside weld composed of small-sized grains can be clearly observed when magnifying fusion line. EQZ appears...
This paper introduces a corona-resistant nano-inorganic/organic insulation material. Chemical constitution and microscopic pattern of the inorganic filler in magnetic wire insulating coating was tested analyzed. The electricity, thermal effect packed nano TiO/sub 2/ powders during course failure investigated from point view utility. When corona resistant modified by suffers damage, layer precipitate can improve electric field distribution increase capacity heat conduction. It provides some...
In this paper, the influence of welding speed on tensile properties AA2024-T3 fibre laser welds was investigated by monitoring deformation behaviour during loading. In-situ micro-tensile testing combined with a high-resolution optical microscope and DIC used to measure strain distribution in narrow weld regions showing characteristics beam limited metallurgical modifications. A chemical etching technique generate micro-scale random speckle pattern revealing microstructure. Such enabled...
Abstract Liver regeneration is an intricate pathophysiological process that has been a subject of great interest to the scientific community for many years. The capacity liver very critical patients with diseases. Therefore, exploring mechanisms and finding good ways improve it are meaningful. Mesencephalic astrocyte-derived neurotrophic factor (MANF), member newly identified factors (NTFs) family, extensively expresses in demonstrated cytoprotective effects during ER stress inflammation....
The experimental of fiber laser welding 6A02 aluminum alloy with filler wire was carried out, and high speed 6m/min used. effects different feeding speeds on cross-section shapes welds, joints' microstructure tensile properties were analyzed. energy melting the base metal to achieve keyhole effect is defined as relative heat input. It affected by speed, which leads changes penetration state coarsening degree joint. joints presents columnar grains near fusion zone mixed (columnar + equiaxed...
6A02 aluminum alloy was welded by fibre laser welding with two different filler wires (ER4043 and ER5356). The weld apperance, microstructure mechanical properties were analysed. results show the course ER4043 is more stable than that ER5356, spatters of former are smaller latter. microsturtrue zone, including columnar-grains near fusion zone mixed microstructures (columnar grains equiaxed grains) in center finer ER5356 ER4043. So average microhardness value higher A great number low melting...
Abstract This paper focused on the welding 1.2 mm thick 2A97 aluminium lithium (Al-Li) alloy plates in T-joint form using fiber laser with ER2319 filler wire. The effects of parameters weld appearance, microstructure and joint mechanical properties were studied systematically, influence including incident beam position angle. shape, microstructure, hardness evaluated by optical microscope micro-hardness test. A uniaxial tensile test was conducted to obtain property welded joints. At...
Laser cutting and joining technology is indispensable as an advanced manufacturing owing to its comprehensive advantages of flexibility, high efficiency, quality; it has a profound impact on the industry. With intelligentization manufacturing, laser will be surely promoted by integration digital technology. This study selects analyzes four specific technologies that are most widely used in industry summarize application status technology, namely, welding, cutting, drilling, marking. The...
A new perspective of localized shear strain accumulation was proposed to elucidate the formation mechanism fine granular area (FGA) generated in a high strength steel under very-high-cycle fatigue (VHCF). On one hand, experiments VHCF negative stress ratio -1 carried out, and microstructure FGA found characterized by using Scanning Electron Microscope, Transmission Microscopy, Kikuchi Diffraction. The results show that consists high-density dislocations, sub-grains, grains with angle grain...
As the third-generation aluminum-lithium alloy developed by China, 2A97 is widely used in aerospace field. However, weak fine equiaxed zone (FEQZ) of weld severely limits its application. In this study, macro- and microscopic characteristics formation mechanism microstructure were investigated under condition large heat input non-autogenous laser welding (NLW) with ER2319 ER4047 filler metals. The results showed that, porosity imperfection 2A97-T3 via NLW could be modified using ER2319....