Nicholas Cox

ORCID: 0000-0001-7442-2829
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About
Contact & Profiles
Research Areas
  • Acute Myocardial Infarction Research
  • Coronary Interventions and Diagnostics
  • Cardiac Imaging and Diagnostics
  • Cardiac Arrest and Resuscitation
  • Heart Failure Treatment and Management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Vascular Procedures and Complications
  • Venous Thromboembolism Diagnosis and Management
  • Emergency and Acute Care Studies
  • Mechanical Circulatory Support Devices
  • Peripheral Artery Disease Management
  • Interpreting and Communication in Healthcare
  • Cardiac Structural Anomalies and Repair
  • Chronic Disease Management Strategies
  • Radiation Dose and Imaging
  • Pharmaceutical Practices and Patient Outcomes
  • Cerebrovascular and Carotid Artery Diseases
  • Health Systems, Economic Evaluations, Quality of Life
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Immunology Research
  • Cardiac Health and Mental Health
  • Healthcare Technology and Patient Monitoring
  • Trauma and Emergency Care Studies
  • Healthcare cost, quality, practices

Western Health
2016-2025

The University of Melbourne
2016-2025

Footscray Hospital
2007-2024

Victoria University
2023

Alfred Health
2021-2022

The University of Texas MD Anderson Cancer Center
2021

Monash University
2019-2020

University College London
2019

University College Hospital
2019

Sunshine Hospital
2019

Background— Sirolimus-eluting stents (SESs) reduce angiographic restenosis in patients with focal, native coronary artery stenoses. This study evaluated the usefulness of SESs complex native-vessel lesions at high risk for restenosis. Methods and Results— Angiographic follow-up 240 days was obtained 701 long (15- to 25-mm) small-diameter (2.5- 3.5-mm) vessels who were randomly assigned treatment or bare-metal (BMSs) SIRIUS trial. Quantitative measurements minimal lumen diameter percent...

10.1161/01.cir.0000150331.14687.4b article EN Circulation 2004-12-21

Background: The success rate of percutaneous coronary intervention (PCI) chronic total occlusions (CTO) is relatively low. Further evaluation CTO lesion with CT angiography (CT‐CA) may help to better select patients that would benefit from revascularization. We aimed test the possible association between failed PCI and transluminal calcification as assessed by CT‐CA. Methods: Patients awaiting were scanned a 16‐slice CT. A cardiologist radiologist lesions on images while an interventional at...

10.1111/j.1540-8183.2007.00275.x article EN Journal of Interventional Cardiology 2007-08-23

ABSTRACT Background Acute myocardial infarction complicated by cardiogenic shock (AMICS) confers short‐term mortality of 40%–50%. Protocolised network management AMICS patients as part a hub‐and‐spoke model supported upstream mechanical circulatory support (MCS) is gaining traction globally to treat AMICS. Method We conducted prospective multicenter study in Melbourne, Australia describing our 5‐year experience utilizing protocolised care for with planned use Impella CP (Abiomed, Danvers,...

10.1002/ccd.31462 article EN Catheterization and Cardiovascular Interventions 2025-02-21

SUMMARY The maximum likelihood (ML) procedure is used to estimate the correlation between a discrete and continuous variable. variable assumed be classification of an unobservable whose joint distribution with observed bivariate normal. As illustration, bodyweight at time mating, number lambs born in flock ewes estimated.

10.2307/2529626 article EN Biometrics 1974-03-01

Health services worldwide face the challenge of providing care for increasingly culturally and linguistically diverse (CALD) populations. The aims this study were to determine whether CALD patients hospitalized with acute heart failure (HF) are at increased risk rehospitalization emergency department (ED) visitation after discharge, compared non-CALD patients, within ascertain impact limited English proficiency (LEP) on outcomes.A cohort 1613 discharged from hospital following an episode HF...

10.1093/ehjqcco/qcz034 article EN European Heart Journal - Quality of Care and Clinical Outcomes 2019-07-22

Importance COVID-19 mRNA vaccine-associated myocarditis has previously been described; however specific features in the adolescent population are currently not well understood. Objective To describe adverse events following immunisation reported any vaccines Victoria, Australia. Design Statewide, population-based study. Setting Surveillance of Adverse Events Following Vaccination Community (SAEFVIC) is vaccine-safety service for Participants All SAEFVIC reports and myopericarditis...

10.1136/bmjpo-2022-001472 article EN cc-by-nc BMJ Paediatrics Open 2022-06-01

Percutaneous coronary intervention (PCI) of saphenous vein grafts (SVG) and native arteries may be associated with embolization particulate debris into the distal microcirculation. The FilterWire uses a polyurethane filter bag contained on radiopaque loop to trap embolic during vessel SVG intervention. objectives this study were assess feasibility safety PCI examine size content captured Early angiographic, in-hospital, 30-day clinical outcomes reviewed in 35 patients 36 lesions treated PCI....

10.1002/ccd.10313 article EN Catheterization and Cardiovascular Interventions 2002-09-30

Nanotechnology produces a wide range of medicinal compounds, including nanoparticulate silver, which are increasingly introduced in various forms for consumer use. As with all potential drug interactions an important consideration ingested silver nanoparticles. Nanoparticulate silver–drug may be mediated through induced oxidative stress liver tissue where the majority systemically bioavailable nanoparticles is found. To investigate whether orally commercially available colloidal nanoproduct...

10.3109/17435390.2014.948092 article EN Nanotoxicology 2014-08-19

Abstract Aims We aimed to assess the impact of severity chronic kidney disease (CKD) with long‐term clinical outcomes in patients undergoing percutaneous coronary intervention (PCI). Methods analyzed data on consecutive PCI enrolled Victorian Cardiac Outcomes Registry (VCOR) from January 2014 December 2018. Patients were stratified into tertiles renal function; estimated glomerular filtration (eGFR) ≥60, 30–59 and < 30 ml/min/1.73 m 2 (including dialysis). The primary outcome was...

10.1002/ccd.29436 article EN Catheterization and Cardiovascular Interventions 2020-12-16

Abstract Aims To evaluate the association of limited English proficiency (LEP) with reperfusion times and outcomes in patients undergoing primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI). Methods results This cohort study included 5385 who underwent PPCI 2013–2017 were prospectively enrolled Victorian Cardiac Outcomes Registry. Data linkage to government administrative datasets was performed identify patients’ preferred spoken language,...

10.1093/ehjqcco/qcz061 article EN European Heart Journal - Quality of Care and Clinical Outcomes 2019-11-27

Unplanned readmissions to hospital after percutaneous coronary intervention (PCI) pose a significant burden the healthcare system and are potentially preventable. In this study, we sought determine incidence of, risk factors for, unplanned within 30 days following PCI. We prospectively collected data on 28,488 patients undergoing PCI between 2013 2019, who were enrolled in state-wide multi-centre Victorian Cardiac Outcomes Registry. Patients' then linked from Department of Health...

10.3390/jcm9103242 article EN Journal of Clinical Medicine 2020-10-10

Bleeding severity in patients undergoing percutaneous coronary intervention (PCI), defined by the Academic Research Consortium (BARC), portends adverse prognosis. We analysed data from 37,866 Australian PCI enrolled Victorian Cardiac Outcomes Registry (VCOR), and investigated association between increasing BARC in-hospital 30-day major cardiac cerebrovascular events (MACCE) (a composite of mortality, myocardial infarction, stent thrombosis, target vessel revascularisation, or stroke)....

10.3390/jcm9051426 article EN Journal of Clinical Medicine 2020-05-11
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