- Congenital Heart Disease Studies
- Viral Infections and Immunology Research
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Cardiac Arrest and Resuscitation
- Cardiovascular Issues in Pregnancy
- Anesthesia and Neurotoxicity Research
- Cardiac Ischemia and Reperfusion
- Pericarditis and Cardiac Tamponade
- Esophageal and GI Pathology
- Cardiac electrophysiology and arrhythmias
- Infant Development and Preterm Care
- Dialysis and Renal Disease Management
- Cardiovascular Effects of Exercise
- Otolaryngology and Infectious Diseases
- Congenital heart defects research
- Kawasaki Disease and Coronary Complications
Royal Children's Hospital
2013-2024
Murdoch Children's Research Institute
2013-2024
The University of Melbourne
2013-2023
Royal Women's Hospital
2014
Royal Ottawa Mental Health Centre
2014
Australian Centre for Heart Health
2008-2010
Monash Medical Centre
2008
Prince Charles Hospital
2007
Royal Brisbane and Women's Hospital
2007
Stobhill Hospital
1997
The aim of this study was to explore the acute psychosocial risk in families with infants undergoing surgery for a congenital heart disease and, secondarily, impact antenatal versus post-natal diagnoses.The sample comprised 39 caregivers (28 mothers) 29 children diagnosed and requiring within first 4 weeks life. Psychosocial measured using Assessment Tool, which adapted include four novel items examining infant factors, namely, sleeping, feeding, crying, bonding difficulties. Parents' after...
Remote Ischemic Preconditioning (RIPC) induced by brief episodes of ischemia the limb protects against multi-organ damage ischemia-reperfusion (IR). Although it has been demonstrated that RIPC affects gene expression, proteomic response to not determined. This study aimed examine changes in plasma proteome. Five healthy adult volunteers had 4 cycles 5 min alternating with reperfusion forearm. Blood samples were taken from ipsilateral arm prior first ischaemia, immediately after each episode...
Abstract Background Exercise training has been shown to increase exercise capacity in survivors of Fontan surgery. The geographic distribution the population a barrier hospital-based programmes. objective this study was establish whether home programme could achieve similar improvements hospital programme. Methods Adolescents with circulation aged 12–19 years were prospectively recruited or Patients underwent cardiopulmonary testing and completed Paediatric Quality Life Inventory at initial...
Importance COVID-19 mRNA vaccine-associated myocarditis has previously been described; however specific features in the adolescent population are currently not well understood. Objective To describe adverse events following immunisation reported any vaccines Victoria, Australia. Design Statewide, population-based study. Setting Surveillance of Adverse Events Following Vaccination Community (SAEFVIC) is vaccine-safety service for Participants All SAEFVIC reports and myopericarditis...
To determine whether conventional coarctation repair results in sustained growth of hypoplastic transverse arches, we examined the follow-up 20 patients operated through a thoracotomy between 1990 and 1995 who had available serial echocardiographic examinations. Mean age at operation was 8.6±5.7 days. In distal arch, maximum change observed early postoperative period thereafter. At last follow-up, no Z-scores less than –2. contrast, only minimal occurred proximal arch (mean Z-score diameter...
Abstract Background Children with functionally univentricular circulations have chronic volume loading of the systemic ventricle, potentially affecting ventricular function. Medications including angiotensin-converting enzyme inhibitors and β-blockers are used to treat dysfunction, despite limited evidence their efficacy in this population. Objective To determine effects on elevated filling pressures children single ventricle physiology. Methods We performed a single-centre, retrospective...
Objectives: Milrinone is an inodilator widely used in the postoperative management of children undergoing cardiac surgery. The literature supporting its inotropic effect sparse. We sought to study milrinone on vasculature and effects ventricular function using wave intensity analysis. also intended evaluate feasibility analysis by bedside. Design: prospective single-center observational study. Setting: PICU a tertiary children’s hospital. Patients: Children (< 18 yr) admitted following...
Abstract Background : C hildren undergoing open heart surgery are at risk of neurological injury. A cohort 35 patients, who had undergone cardiac during infancy, a significant reduction in Bayley Scale Infant Development scores 12-month assessment. This has now reached an appropriate age to reassess developmental progress. Methods Detailed psychometric testing was conducted on 20 children from the original using Weschler Preschool and Primary Intelligence, Wide Range Assessment Memory...
OBJECTIVES: Pulmonary artery banding (PAB) remains in the armamentarium of techniques for several congenital cardiac anomalies, but necessitates a reoperation eventual removal. We sought to assess efficacy an absorbable PAB obviating requirement reoperation. METHODS: From 2003 2015, 45 consecutive patients with median age 1.6 months (2 days–11 months) underwent placement polydioxanone PAB. In 28 (62%), band was placed concomitantly ventricular septal defect (VSD) closure and 17 (38%), sole...
To describe the results of Tenckhoff catheter salvage by a modified, closed, stiff-wire manipulation technique without use general anesthesia or fluoroscopy, and compare this with previously described techniques.Retrospective study in patients treated continuous ambulatory peritoneal dialysis (CAPD) over 41-month period.Renal unit an inner city hospital.Eighteen using CAPD who had 22 episodes outflow failure due to radiologically confirmed malposition straight two-cuff catheters.Closed...