A5036400999- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Interpreting and Communication in Healthcare
- SARS-CoV-2 detection and testing
- Heart Failure Treatment and Management
- Lung Cancer Treatments and Mutations
- Acute Myocardial Infarction Research
- Biosensors and Analytical Detection
- Pancreatic and Hepatic Oncology Research
- Cardiovascular Issues in Pregnancy
- Adrenal and Paraganglionic Tumors
- Healthcare Systems and Technology
- Global Cancer Incidence and Screening
- Emergency and Acute Care Studies
- Prostate Cancer Diagnosis and Treatment
- Delphi Technique in Research
- Lung Cancer Research Studies
- Advanced biosensing and bioanalysis techniques
- Research Data Management Practices
- Quality Function Deployment in Product Design
- Respiratory viral infections research
- Mechanical Circulatory Support Devices
- Ethics in Clinical Research
- Lipoproteins and Cardiovascular Health
- RNA modifications and cancer
University of Colorado Denver
1976-2024
Monash University
2015-2021
The Alfred Hospital
2017
Monash Alfred Psychiatry Research centre
2015
Denver Health Medical Center
1976
ABSTRACT The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is due to the high rates transmission by individuals who are asymptomatic at time 1, . Frequent, widespread testing population for SARS-CoV-2 essential suppress viral transmission. Despite increases in capacity, multiple challenges remain deploying traditional reverse transcription and quantitative PCR (RT-qPCR) tests scale required screening individuals. We have developed SwabSeq, a high-throughput...
Recent discoveries in cancer research have revealed a plethora of clinically actionable mutations that provide therapeutic, prognostic and predictive benefit to patients. The feasibility screening as part the routine clinical care patients remains relatively unexplored demonstration massively parallel sequencing (MPS) tumours general population is required assess its value towards health-care system. Cancer 2015 study large-scale, prospective, multisite cohort newly diagnosed from Victoria,...
To assess the external validity of mapping algorithms for predicting EQ-5D-3L utility values from EORTC QLQ-C30 responses not previously validated and to whether statistical models applied are better suited EQ-5D-3L.In total, 3866 observations 1719 patients a longitudinal study (Cancer 2015) were used validate existing algorithms. Predictive accuracy was compared using root mean squared error, absolute error across range, 10 tumor-type specific samples as well differences between estimated...
Abstract Aims To evaluate the association of limited English proficiency (LEP) with reperfusion times and outcomes in patients undergoing primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI). Methods results This cohort study included 5385 who underwent PPCI 2013–2017 were prospectively enrolled Victorian Cardiac Outcomes Registry. Data linkage to government administrative datasets was performed identify patients’ preferred spoken language,...
Unplanned readmissions to hospital after percutaneous coronary intervention (PCI) pose a significant burden the healthcare system and are potentially preventable. In this study, we sought determine incidence of, risk factors for, unplanned within 30 days following PCI. We prospectively collected data on 28,488 patients undergoing PCI between 2013 2019, who were enrolled in state-wide multi-centre Victorian Cardiac Outcomes Registry. Patients' then linked from Department of Health...
“Cancer 2015” is a longitudinal and prospective cohort. It phased study whose aim was to pilot recruiting 1000 patients during phase 1 establish the feasibility of providing population-based genomics Newly diagnosed adult with solid cancers, residual tumour material for molecular testing, were recruited into cohort collection dataset containing clinical, pathology, health resource use outcomes data. 1685 have been over almost 3 years from five hospitals. Thirty-two percent are aged between...
PURPOSE To detail the process for importing a defined data set into centralized global registry via secure file transfer platform and to understand barriers establishment of registry. RESULTS A bespoke solution was developed allow transmission from international local centers repository. Data elements included in import template were drawn existing International Consortium Health Outcome Measurement variables refined ensure accurate benchmarking as well feasibility completeness. The...
Abstract Background Healthcare providers worldwide increasingly must face the challenge of providing care to culturally and linguistically diverse patients who may have limited proficiency in primary working language country they are in. This discordance lead delayed treatment worse outcomes. The impact English (LEP), a predominantly English-speaking like Australia, on time reperfusion outcomes following PCI for STEMI has not been previously studied. Objective Among undergoing STEMI, compare...
Abstract Background Unplanned hospital readmissions post-percutaneous coronary intervention (PCI) result in a significant burden to the healthcare system and adverse patient outcomes. Understanding factors associated with 30-day readmission rates may help reduce this burden. Data linkage of clinical quality registry data routinely collected administrative datasets assist overcoming resource constraints that limit collection follow-up but is currently under-utilised worldwide. Objective To...
IntroductionMonash University’s health researchers are at the forefront of Health, Epidemiological and Translational research. Powered by research funding over $69 million per year, Monash encompasses 13+ registries, 44+ clinical trials 47+ cohort studies underpinned complex multimodal, large often sensitive datasets. Many these activities occurring in isolation. Opportunities exist to better deliver higher impact scale through capacity building data sharing.
 Objectives ApproachWe have...