Brett Doble

ORCID: 0000-0002-4948-8831
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About
Contact & Profiles
Research Areas
  • Health Systems, Economic Evaluations, Quality of Life
  • CAR-T cell therapy research
  • Cancer Genomics and Diagnostics
  • Healthcare Policy and Management
  • Cardiac Valve Diseases and Treatments
  • Obesity, Physical Activity, Diet
  • Consumer Attitudes and Food Labeling
  • Biosimilars and Bioanalytical Methods
  • Bariatric Surgery and Outcomes
  • Nutritional Studies and Diet
  • Genomics and Rare Diseases
  • Economic and Financial Impacts of Cancer
  • Lung Cancer Treatments and Mutations
  • Infective Endocarditis Diagnosis and Management
  • Lymphoma Diagnosis and Treatment
  • Healthcare cost, quality, practices
  • Palliative Care and End-of-Life Issues
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Body Contouring and Surgery
  • Obesity and Health Practices
  • Chronic Lymphocytic Leukemia Research
  • Medication Adherence and Compliance
  • Atrial Fibrillation Management and Outcomes
  • Aortic Disease and Treatment Approaches
  • Healthcare Systems and Technology

Kite (United States)
2024

University of Oxford
2017-2023

Duke-NUS Medical School
2019-2022

National University of Singapore
2019-2020

Garvan Institute of Medical Research
2016-2020

Institute of Health Services and Policy Research
2020

University of Cambridge
2016-2019

RELX Group (United Kingdom)
2018

RELX Group (United States)
2018

City, University of London
2018

The objective of this trial was to test two promising front-of-pack nutrition labels, 1) the United Kingdom’s Multiple Traffic Lights (MTL) label and 2) France’s Nutri-Score (NS), relative a no-label control. We hypothesized that both labels would improve diet quality but NS be more effective due its greater simplicity. tested hypothesis via an online grocery store using 3 × crossover (within-person) design with 154 participants. Outcomes assessed within person regression models include...

10.3390/nu11092236 article EN Nutrients 2019-09-17

It has been argued that generic health-related quality of life measures are not sensitive to certain disease-specific improvements; condition-specific preference-based may offer a better alternative. This paper assesses the validity, responsiveness and sensitivity cancer-specific measure, EORTC-8D, relative EQ-5D-3L. A longitudinal prospective population-based cancer genomic cohort, Cancer 2015, was utilised in analysis. EQ-5D-3L EORTC QLQ-C30 (which gives EORTC-8D values) were asked at...

10.1007/s11136-016-1443-y article EN cc-by Quality of Life Research 2016-11-09

Background and objective Up-to-date economic burden of asthma in Singapore is currently unknown. Methods We quantify the per capita total annual costs for adults children by level symptom control (uncontrolled, partly controlled, well controlled) via a cross-sectional online survey administered to national web panel. Participants were asked about healthcare utilisation, days missed from work, reduced productivity due their symptoms. These values then monetised multiplied prevalence estimates...

10.1136/bmjresp-2020-000654 article EN cc-by-nc BMJ Open Respiratory Research 2021-03-01

Background Bleeding among populations undergoing percutaneous coronary intervention or artery bypass grafting and conservatively managed patients with acute syndrome exposed to different dual antiplatelet therapy triple (i.e. plus an anticoagulant) has not been previously quantified. Objectives The objectives were estimate hazard ratios for bleeding regimens, resources the associated costs of treating events, extend existing economic models cost-effectiveness therapy. Design study was...

10.3310/mnjy9014 article EN publisher-specific-oa Health Technology Assessment 2023-05-01

Over the past decade there have been remarkable advancements in understanding of molecular underpinnings malignancy. Methods testing capable elucidating patients' profiles are now readily available and is an increased desire to incorporate information derived from such tests into treatment selection for cancer patients. This has led more appropriate application existing treatments as well development a number innovative highly effective or what known collectively precision medicine. The...

10.1080/00365513.2016.1206437 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2016-07-13

To assess the external validity of mapping algorithms for predicting EQ-5D-3L utility values from EORTC QLQ-C30 responses not previously validated and to whether statistical models applied are better suited EQ-5D-3L.In total, 3866 observations 1719 patients a longitudinal study (Cancer 2015) were used validate existing algorithms. Predictive accuracy was compared using root mean squared error, absolute error across range, 10 tumor-type specific samples as well differences between estimated...

10.1177/0272989x18797588 article EN Medical Decision Making 2018-09-18

Background The increasing difficulty experienced by general practices in meeting patient demand is leading to new approaches being tried, including greater use of telephone consulting. Objectives To evaluate a ‘telephone first’ approach, which all patients requesting practitioner (GP) appointment are asked speak GP on the first. Methods study used controlled before-and-after (time-series) approach using national reference data sets; it also incorporated economic and qualitative elements....

10.3310/hsdr07170 article EN publisher-specific-oa Health Services and Delivery Research 2019-05-01

Abstract Background Several front-of-pack (FOP) labels identify healthier options by comparing foods within product categories. Alternative approaches label across Which approach is superior remains unknown. The objective of this study was to test the effect a within-category versus across-category FOP lower calorie on 1) percentage labeled products purchased, 2) several measures calories purchased (total, per dollar and serving), 3) total spending. We also tested moderating effects hunger...

10.1186/s12889-020-8434-1 article EN cc-by BMC Public Health 2020-03-12
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