A5066867089- Ethics in Clinical Research
- Hydrogen's biological and therapeutic effects
- Pharmacovigilance and Adverse Drug Reactions
- Health Systems, Economic Evaluations, Quality of Life
- Pregnancy and Medication Impact
- Lung Cancer Research Studies
- Anesthesia and Neurotoxicity Research
- Bone health and treatments
- Radiation Detection and Scintillator Technologies
- Reproductive Health and Contraception
- Radiation Therapy and Dosimetry
- Respiratory Support and Mechanisms
- Cancer Diagnosis and Treatment
- Advanced Chemical Sensor Technologies
- Pharmaceutical Practices and Patient Outcomes
- Brain Metastases and Treatment
- Advanced Radiotherapy Techniques
- Nanoplatforms for cancer theranostics
- Bone and Joint Diseases
- Thermal Regulation in Medicine
Centre Hospitalier Universitaire de Grenoble
2020-2024
Université Grenoble Alpes
2009
Brain metastasis impacts greatly on patients' quality of life and survival. The phase I NANO-RAD trial assessed the safety maximum tolerated dose systemic administration a novel gadolinium-based nanoparticle, AGuIX, in combination with whole brain radiotherapy patients multiple metastases not suitable for stereotactic radiotherapy.Patients measurable received escalating doses AGuIX nanoparticles (15, 30, 50, 75, or 100 mg/kg intravenously) day initiation WBRT (30 Gy 10 fractions) 5 cohorts 3...
Abstract Introduction The Covid-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has triggered a serious global health crisis, resulting in millions of reported deaths since its initial identification China November 2019. disparities immunization access emphasize urgent need for ongoing research into therapeutic interventions. This study focuses on potential use molecular dihydrogen (H2) inhalation as an adjunctive treatment Covid-19. H2 therapy shows...
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), has triggered a serious global health crisis, resulting in millions of reported deaths since its initial identification China November 2019. disparities immunization access emphasize urgent need for ongoing research into therapeutic interventions. This study focuses on potential use molecular dihydrogen (H2) inhalation as an adjunctive treatment COVID-19. H2 therapy shows promise...
Background/Aims The Clinical Trials Coordination and Facilitation Group has issued recommendations on contraception pregnancy testing to help sponsors meet regulatory expectations harmonize practices limit embryofetal risks in clinical trials. Our objective was assess the compliance of French academic trials with these describe mitigation measures required by their Methods A cross-sectional study performed drug authorized national competent authority between January 2015 June 2018. We...