Akihiro Kakimoto

ORCID: 0000-0001-7452-629X
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About
Contact & Profiles
Research Areas
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Total Knee Arthroplasty Outcomes
  • Functional Brain Connectivity Studies
  • Medical Imaging Techniques and Applications
  • Hip disorders and treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Nicotinic Acetylcholine Receptors Study
  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Image and Signal Denoising Methods
  • Tendon Structure and Treatment
  • Robotics and Automated Systems
  • Advanced Neuroimaging Techniques and Applications
  • Peripheral Nerve Disorders
  • Satellite Communication Systems
  • Virtual Reality Applications and Impacts
  • Geophysics and Sensor Technology
  • Radiation Dose and Imaging
  • Traumatic Brain Injury Research
  • Nutrition and Health in Aging
  • Photoacoustic and Ultrasonic Imaging
  • Simulation-Based Education in Healthcare
  • Elbow and Forearm Trauma Treatment
  • Stoma care and complications

Hamamatsu University School of Medicine
2011-2025

Morinomiya University of Medical Sciences
2020-2025

Hamamatsu Photonics (Japan)
2011-2020

Rakuwakai Otowa Hospital
2003-2010

Shiga University of Medical Science
1996

The benefits of robotic techniques for implanting femoral components during THA are still controversial.The purpose this study was to prospectively compare the results and complications robotic-assisted hand-rasping stem implantation techniques.The minimum followup 5 years (mean, 67 months; range, 60-85 months). One hundred forty-six primary THAs on 130 patients were included in study. Robot-assisted performed 75 hips a technique used 71 hips.At 2 3 postoperatively, Japanese Orthopaedic...

10.1007/s11999-009-1158-2 article EN Clinical Orthopaedics and Related Research 2009-11-04

With a large database, we aimed to evaluate sex-specific distinctive changes in brain glucose metabolism and morphology during normal aging using MRI (18)F-FDG PET.A total of 963 cognitively healthy adults were included this study. All subjects completed medical questionnaire, took the mini-mental state examination, underwent whole-body PET. The MR PET images statistically analyzed 3-dimensional stereotactic surface projection. corrected for whole-brain pixel value identify regions with...

10.2967/jnumed.115.166439 article EN Journal of Nuclear Medicine 2015-11-25

Although convolutional neural networks (CNNs) demonstrate the superior performance in denoising positron emission tomography (PET) images, a supervised training of CNN requires pair large, high-quality PET image datasets. As an unsupervised learning method, deep prior (DIP) has recently been proposed; it can perform with only target image. In this study, we propose innovative procedure for DIP approach four-dimensional (4D) branch architecture end-to-end to denoise dynamic images. Our...

10.1088/1361-6560/abcd1a article EN Physics in Medicine and Biology 2020-11-23

In Japan, task shifting and sharing are promoted to reduce the workload of physicians. Radiological technologists have been assigned new responsibilities, such as securing venous access for radiopharmaceutical administration. This study aimed develop a prototype Virtual Reality (VR) training system that allows safe repeatable radiological technologists. Additionally, educational effectiveness VR was evaluated, concentration levels participants were assessed using multiple physiological...

10.1371/journal.pone.0321101 article EN cc-by PLoS ONE 2025-03-31

Abstract The ROBODOC system has provided better fit and fill of the stem less destruction bony architecture than with manual surgery. These benefits might affect femoral periprosthetic bone remodeling. We evaluated effects robotic milling in cementless total hip arthroplasty (THA) a longitudinal 24‐month follow‐up study using dual energy X‐ray absorptiometry (DEXA) plain radiographs 29 patients (31 hips) after THA 24 (27 same design. To minimize influence other factors on remodeling, only...

10.1002/jor.20376 article EN Journal of Orthopaedic Research® 2007-04-24

Background: The α7 subtype of the nicotinic acetylcholine receptor (nAChR) is considered important in higher cognitive functions, and cholinergic loss underpins pathophysiology Alzheimer’s disease (AD). However, relationships between nAChR function clinical functions or amyloid-β (Aβ) deposition remain to be explored living AD brain. Objective: We aimed elucidate relationship availability specific region decline Aβ-confirmed Methods: Twenty patients ten age-matched healthy subjects were...

10.3233/jad-170591 article EN Journal of Alzheimer s Disease 2018-01-23

Dynamic positron emission tomography (PET) scans of short-time frames are required to quantitatively estimate the uptake PET ligands. Because such short-frame tend be noisy, we propose kinetics-induced block matching and 5-D transform domain filtering (KIBM5D) specialized for dynamic image denoising. In proposed algorithm, (KIBM) alternately repeated in two cascading stages. each stage KIBM5D, all time included a patch KIBM collect similar patch-wise activity curves. These 4-D patches then...

10.1109/trpms.2020.3000221 article EN IEEE Transactions on Radiation and Plasma Medical Sciences 2020-06-05

MATSUMOTO, KEIJI M.D.†; HUKUDA, SINSUKE FUJITA, MOTOFUMI KAKIMOTO, AKIHIRO TACHIBANA, SHIN-ICHI M.D.†, OTSU, SHIGA, JAPAN Author Information

10.2106/00004623-199602000-00015 article EN Journal of Bone and Joint Surgery 1996-02-01

Objective: The purpose of this study was to propose our CT-based planning approach for knee arthroplasty on the basis femoral flexion-extension (FE) axis, and evaluate whether valid by comparing results with those obtained using conventional anterior-referenced planning.

10.3109/10929080701882580 article EN Computer Aided Surgery 2008-01-01

Purpose We devised a new computer-aided diagnosis method to segregate dementia using one estimated index (Total Z score) derived from the Brodmann area (BA) sensitivity map on stereotaxic brain atlas. The purpose of this study is investigate its accuracy differentiate patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) normal adults (NL). Methods studied 101 (NL: 40, AD: 37, MCI: 24) who underwent 18FDG positron emission tomography (PET) measurement. divided NL and AD...

10.1371/journal.pone.0025033 article EN cc-by PLoS ONE 2011-09-26

Background:Amyloid imaging with positron emission tomography (PET) often comes glucose metabolic in diagnosis of Alzheimer’s disease (AD). Objective:The present purpose was to explore the clinical valence early amyloid-β (Aβ) PET scans determine whether they could substitute for other biomarkers (early and delayed Aβ images 11C-Pittsburgh compound B (PIB) 18F-fluorodeoxyglucose (FDG) images) AD spectrum. Methods:Thirty healthy control subjects, 20 patients mild cognitive impairment, 45...

10.3233/jad-181188 article EN Journal of Alzheimer s Disease 2019-05-14

The effects of lead equivalent and lens area radiation-protective eyewear on exposure control were examined. simulated patient underwent 10-min X-ray fluoroscopy, the dose surgeon wearing radiation protection glasses was measured using dosemeters attached to corner eye eyeball. In total, 10 types selected for measurement. Correlation analysis in with equivalence performed. negatively correlated lens. eyeball showed a strong negative correlation equivalence. Lens worn at may overestimate eye....

10.1093/rpd/ncad103 article EN Radiation Protection Dosimetry 2023-03-07

To minimize motion-related distortion of reconstructed images, conventional positron emission tomography (PET) measurements the brain inevitably require a firm and tight head restraint. While such restraint is now routine procedure in imaging, physiological psychological consequences resulting from have not been elucidated. address this problem, we developed restraint-free PET system conducted scans under both restrained non-restrained conditions. We examined whether during could alter...

10.1016/j.neuroimage.2020.117434 article EN cc-by NeuroImage 2020-10-08

Idiopathic hypoparathyroidism (IHP) is accompanied by cognitive impairment. We report the case of a 70-year-old IHP patient with disturbance. Brain computed tomography showed bilateral calcification in basal ganglia, thalamus, and cerebellum. Neuropsychological assessment revealed low scores for intelligence, memory, perseverative errors. positron emission significant reduction [18F]-Fludeoxyglucose (FDG) uptake frontal, left temporal parietal cortices, along marked [11C]-flumazenil binding...

10.2169/internalmedicine.54.4295 article EN Internal Medicine 2015-01-01

Objective: The purpose of this study was to propose our CT-based planning approach for knee arthroplasty on the basis femoral flexion-extension (FE) axis, and evaluate whether valid by comparing results with those obtained using conventional anterior-referenced planning.Materials Methods: Virtual implantation a sagittal single-radius component performed in 34 normal knees. transepicondylar axis (TEA) identified as FE modified coronal plane intersect mechanical at right angle, if necessary....

10.1080/10929080701882580 article EN Computer Aided Surgery 2008-01-01

Peripheral nerve tension is known to be related the pathophysiology of neuropathy; however, assessing this difficult in a clinical setting. In study, we aimed develop deep learning algorithm for automatic assessment tibial using B-mode ultrasound imaging. To algorithm, used 204 images three positions: maximum dorsiflexion position and −10° −20° plantar flexion from dorsiflexion. The were taken 68 healthy volunteers who did not have any abnormalities lower limbs at time testing. was manually...

10.3390/s23104855 article EN cc-by Sensors 2023-05-18

Introduction Brain amyloid-β protein (Aβ) deposition is a key pathology of Alzheimer's disease (AD). Cholinergic degeneration, including reductions in α7 nicotinic acetylcholine receptors (α7-nAChR), also known as pathophysiology AD. Recent imaging studies have shown cognitively normal subjects with Aβ depositions, indicating missing link between and cognitive decline. Objectives To clarify relationships among the burden, α7-nAChR availability, declines Aims measure brain availability same...

10.1016/j.eurpsy.2016.01.468 article EN European Psychiatry 2016-03-01
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