A5021355874- Neuroscience and Neuropharmacology Research
- Maternal Mental Health During Pregnancy and Postpartum
- Schizophrenia research and treatment
- Epilepsy research and treatment
- Metabolism and Genetic Disorders
- Adolescent and Pediatric Healthcare
- Advanced MRI Techniques and Applications
- Mitochondrial Function and Pathology
- Autism Spectrum Disorder Research
- Diet and metabolism studies
- Child and Adolescent Psychosocial and Emotional Development
- Obsessive-Compulsive Spectrum Disorders
- Neurological disorders and treatments
- Gestational Diabetes Research and Management
- Growth Hormone and Insulin-like Growth Factors
- Salivary Gland Disorders and Functions
- Stuttering Research and Treatment
- Mental Health Treatment and Access
- Estrogen and related hormone effects
- Infant Health and Development
- Treatment of Major Depression
- Medical Imaging and Analysis
- Anatomy and Medical Technology
- Nuclear reactor physics and engineering
- Child Abuse and Related Trauma
Asahikawa Medical University
2024
Japan Atomic Energy Agency
2024
Hamamatsu University School of Medicine
1994-2017
Hiratsuka City Hospital
2004
Imperial Household Agency
1990-1993
University of British Columbia
1989
Hokkaido University
1986
Genome-wide association studies (GWASs) have identified several susceptibility loci for bipolar disorder (BD) and shown that the genetic architecture of BD can be explained by polygenicity, with numerous variants contributing to BD. In present GWAS (Phase I/II), which included 2964 61 887 control subjects from Japanese population, we detected a novel locus at 11q12.2 (rs28456, P=6.4 × 10−9), region known contain regulatory genes plasma lipid levels (FADS1/2/3). A subsequent meta-analysis...
To discuss the relationship between obsessive-compulsive symptoms and a right orbitofrontal lesion.Single case report.A 59-year-old man developed disorder (OCD) after his head injury. Magnetic resonance imaging brain scans showed small contusion in region, single-photon emission computed tomography revealed hypoperfusion blood flow at same region.The OCD that present may be attributable primarily to hypofunction lesion localized area. Although caution is needed for interpretation of...
Objective: Olfactory reference syndrome (ORS) in the Western literature is characterized as preoccupation with idea that body emits a foul odor. Japanese patients feature similar to ORS have long been recognized jiko‐shu‐kyofu , which believed be culture‐bound and specific Japan. The aim of study was clarify relationship between two separate syndromes had independently culturally different settings. Method: phenomenology treatment seven were described. A then compared ORS. Results: In our...
We investigated whether antenatal factors in mothers would increase the risk of schizophrenia offspring, and also examined any relationship between these histories obstetric complications (OCs).Using Mother Child Health Handbooks 52 patients with 284 healthy subjects, we evaluated risk-increasing effects frequency care visits mothers' body mass index (BMI) at both early late pregnancy.In logistic regression analysis, there was a significant association number disorder; an unit corresponds to...
Burning mouth syndrome (BMS) is an orofacial pain disorder characterized by a chronic, idiopathic burning sensation of the oral mucosa that mostly affects middle-aged women. Although both psychological and neuropathological factors have been postulated to underlie BMS, pathogenic mechanism condition remains controversial, as do treatment strategies.A single case was reported.Ms A, 66-year-old woman with BMS type 1, which daily associated circadian variation, underwent electroconvulsive...
Background. Many previous studies have shown that individuals who develop schizophrenia in adult life are more likely than normal controls to a history of obstetric complications (OCs) at birth. However, little attention has been paid the involvement OCs risk developing childhood-onset (COS). In our earlier report, we found an association between and development COS. this study, determined whether could be replicated another, independent set patients with Methods. OCs, birth weight...
It is well known that complex partial seizures of temporal origin may evolve into secondarily generalized convulsive seizures. For this reason, amygdaloid kindling, which begins with limbic and culminates in convulsions, considered to be a useful model for examination mechanisms underlying the development originating from non-motor structure such as amygdala. Recent observations made our laboratory are relevant anatomic network expression generalization amygdala-onset Specifically,...
We investigated whether peripheral pulse synchronization (PPUS) can be an alternate method for electrocardiographic (ECGS) in measuring myocardial T1 values cardiac magnetic resonance imaging (CMRI).
Nuclear decommissioning is crucial as nuclear facilities become old. This trend has recently accelerated, particularly following the accident at Fukushima Daiichi Power Station, Tokyo Electric Holdings. New technologies are required to improve safety, save time, and reduce costs. An example γ-ray/X-ray (radiation photon) spectroscopy, which provides information on types of radionuclides with radiation photon emissions. A feasibility study spectroscopy in conjunction reactor dosimetry a...
Introduction Brain amyloid-β protein (Aβ) deposition is a key pathology of Alzheimer's disease (AD). Cholinergic degeneration, including reductions in α7 nicotinic acetylcholine receptors (α7-nAChR), also known as pathophysiology AD. Recent imaging studies have shown cognitively normal subjects with Aβ depositions, indicating missing link between and cognitive decline. Objectives To clarify relationships among the burden, α7-nAChR availability, declines Aims measure brain availability same...
Aim: The posterior orbit contains a number of important and vulnerable structures, including the optic nerve, ophthalmic artery vein, ocular muscles their motor nerves, which make surgical access to lesions in this region quite difficult. Transfrontal, transfrontal-ethmoidal, transmaxillary procedures have disadvantage possible injuries nontumor whereas an endoscopic endonasal transethmoidal approach is minimally invasive surgery for orbital retrobulbar lesions.