A5002229333- Food composition and properties
- Phytochemicals and Antioxidant Activities
- Gut microbiota and health
- Protein Hydrolysis and Bioactive Peptides
- Fungal Biology and Applications
- PI3K/AKT/mTOR signaling in cancer
- Proteins in Food Systems
- Genetic factors in colorectal cancer
- Genomics, phytochemicals, and oxidative stress
- Polysaccharides and Plant Cell Walls
- Cancer-related molecular mechanisms research
- Colorectal Cancer Treatments and Studies
- Perovskite Materials and Applications
- Polysaccharides Composition and Applications
- Luminescence Properties of Advanced Materials
- Pharmacological Effects of Natural Compounds
- Tea Polyphenols and Effects
- Liver Disease Diagnosis and Treatment
- Advanced Sensor and Control Systems
- Metabolism, Diabetes, and Cancer
- Gas Sensing Nanomaterials and Sensors
- Inflammatory Bowel Disease
- Mercury impact and mitigation studies
- Advanced Photocatalysis Techniques
- Microencapsulation and Drying Processes
Central South University of Forestry and Technology
2016-2025
Central South University
2016-2025
Zhejiang Chinese Medical University
2024-2025
Beijing Aerospace Flight Control Center
2025
Chongqing Medical University
2025
Qilu Hospital of Shandong University
2024
Hunan University of Humanities, Science and Technology
2016-2024
Chengdu University of Information Technology
2023-2024
Centers for Disease Control and Prevention
2023-2024
Second Xiangya Hospital of Central South University
2024
In 100 primary colorectal carcinomas, we demonstrate by array comparative genomic hybridization (aCGH) that 33% show DNA copy number (DCN) loss involving PARK2 , the gene encoding PARKIN, E3 ubiquitin ligase whose deficiency is responsible for a form of autosomal recessive juvenile parkinsonism. located on chromosome 6 (at 6q25–27), with one lowest overall frequencies alterations recorded in cancers. The deletions are mostly focal (31% ∼0.5 Mb average), heterozygous, and maximum incidence...
With the increasing development of biotechnology and informatics technology, publicly available data in chemistry biology are undergoing explosive growth. Such wealthy information these needs to be extracted transformed useful knowledge by various mining methods. Considering amazing rate at which accumulated fields, new tools that process interpret large complex interaction increasingly important. So far, there no suitable toolkits can effectively link chemical biological space view...
During 2000-2016, the suicide rate among U.S. working age population (persons aged 16-64 years) increased 34%, from 12.9 per 100,000 to 17.3 (https:// www.cdc.gov/injury/wisqars).To better understand different occupational groups and inform prevention efforts, CDC analyzed deaths by Standard Occupational Classification (SOC) major for decedents years 17 states participating in both 2012 2015 National Violent Death Reporting System (NVDRS) (https://www.cdc.gov/violenceprevention/nvdrs).The...
In Western countries and China, the dietary habit of high calories usually results in hyperlipidemia, which is closely associated with cardiovascular diseases. study, we investigated antihyperlipidemic effect oryzanol its molecular mechanism fat diet (HFD) mouse model. total, 60 ICR mice were randomly divided into control group, HFD HFD+Ory group. The from group additionally fed 100 mg/kg by intragastric administration. Our data indicated that treatment for 10 weeks significantly reduced...
Oral administration of oat β-glucan ameliorates DSS induced colitis in mice by decreasing the expression inflammatory cytokines TNF-α, IL-1β, IL-6 and iNOS.
Hyperlipidemia occurs very often in modern society along with a high calorie intake and is regarded as one of the greatest risk factors for prevalence cardiac vascular disease (CVD). In this study, we investigated anti-hyperlipidemic effect rice bran polysaccharides (RBP) its mechanism fat diet animal model. 60 ICR mice were randomly divided into 3 groups, which included Control, HFD (high diet) + RBP, each group 20 mice. The control was fed standard while other two groups HFD. addition, RBP...
A high fat and cholesterol diet (HFCD) can modulate the gut microbiota, which is closely related with hypercholesterolemia. This study aimed to explore anti-hypercholesterolemia effect of oryzanol, investigate whether function oryzanol associated microbiota metabolites. 16S rRNA ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry were applied for untargeted metabolomics, respectively. The results showed that HFCD significantly upregulated body accumulation...
The health benefits of anthocyanins have attracted extensive research interest. However, are sensitive to certain environmental and gastrointestinal conditions low oral bioavailability. It has been reported that delivery systems made in different ways could improve the stability, bioavailability bioactivity anthocyanins. This present review summarizes factors affecting stability reasons for poor bioavailability, various technologies encapsulation including microcapsules, nanoemulsions,...
Brown rice (BR) is a traditional health food being rich in various active substances, which have effective preventive and therapeutic effects on many diseases. In this review, we systemically summarized the efficacy of BR cardiovascular diseases (CVDs), hyperlipidemia, hypertension, diabetes, obesity, osteoporosis, neurodegenerative diseases, cancer, immune disorders, inflammation, anxiety, liver stomach damage, etc. Underlying mechanisms also been analyzed, include regulating lipid...
TGFβ1 is very important in the synthesis and degradation of extracellular matrix, also mediation human lung fibroblasts proliferation, miR-29 plays an role this process. To explore interactions family members TGFβ1, effects transforming growth factor on expression whether involved pro-survival signaling pathways mediated by were examined fibroblasts. Treatment embryonic fibroblast cell line IMR90 with caused a decrease miR-29a/b/c real-time PCR analysis. stimulation increased colony...
Scope In this study, the anti-inflammatory effects and molecular mechanism of alliin were analyzed in dextran sulfate sodium (DSS)-induced colitis mice lipopolysaccharide-stimulated RAW264.7 cell model. Methods The phenotype was recorded DSS-induced and/or (500 mg/kg) groups. Histopathological alterations by H&E staining. MPO MDA colon tissues measured. mRNA expression levels inflammatory factors determined qRT-PCR, protein expressions or activation kinases Western blotting. Results Oral...