Mingzhi Li

ORCID: 0000-0001-7490-5433
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About
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Research Areas
  • Mosquito-borne diseases and control
  • Monoclonal and Polyclonal Antibodies Research
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Polysaccharides and Plant Cell Walls
  • Herpesvirus Infections and Treatments
  • Fungal Biology and Applications
  • Osteoarthritis Treatment and Mechanisms
  • COVID-19 diagnosis using AI
  • Reconstructive Surgery and Microvascular Techniques
  • Spondyloarthritis Studies and Treatments
  • Facial Nerve Paralysis Treatment and Research
  • Herbal Medicine Research Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Ear Surgery and Otitis Media
  • Obesity, Physical Activity, Diet
  • Artificial Intelligence in Healthcare
  • Infrared Thermography in Medicine
  • Virtual Reality Applications and Impacts
  • Gene Regulatory Network Analysis
  • Diabetic Foot Ulcer Assessment and Management
  • Lung Cancer Treatments and Mutations
  • Winter Sports Injuries and Performance
  • Foot and Ankle Surgery
  • Single-cell and spatial transcriptomics

Harbin Veterinary Research Institute
2023-2025

Chinese Academy of Agricultural Sciences
2023-2024

North China Institute of Science and Technology
2021-2023

Jiangxi Agricultural University
2022

Jiangxi Provincial People's Hospital
2020

State Key Laboratory of Food Science and Technology
2020

Nanchang University
2020

Central South University
2018

Beijing Chest Hospital
2017

Capital Medical University
2017

Lentinula edodes (L. edodes) is a type of edible mushroom which known to beneficially support the immune system. In this study, three polysaccharide fractions (F1, F2 and F3) were isolated from L. water extracts. Their molecular weights distribution (F1 > their immunomodulatory properties investigated. Thymus index, thickness footpad, proliferation splenocytes, immunoglobulin (Ig) content cytotoxicity natural killer (NK) cells measured evaluate effects polysaccharides. All protected host...

10.1016/j.jff.2020.103791 article EN cc-by-nc-nd Journal of Functional Foods 2020-01-24

Introduction: Early childhood obesity in China has become a pressing public health concern. A substantial barrier to healthy weight management is poor parental recognition of child overweight. This study examined the relationship between caregiver perceptions and dietary practices. Methods: total 364 children 2 6 years old from six urban preschools Changsha (China) were included cross-sectional study. Information on household demographics, behaviors, attitudes was collected through...

10.3390/ijerph15040716 article EN International Journal of Environmental Research and Public Health 2018-04-11

The pseudorabies virus (PRV) TJ strain, a variant of PRV, induces more severe neurological symptoms and higher mortality in piglets mice than the PRV SC strain isolated 1980. However, mechanism underlying responsible for discrepancy virulence between these strains remains unclear. Our study investigated differences neurotropism using both vitro vivo models. We discovered that enters neural cells efficiently SC. Furthermore, we found has indistinguishable genomic DNA replication capability...

10.1016/j.jbc.2023.105347 article EN cc-by Journal of Biological Chemistry 2023-10-12

Abstract In order to effectively upgrade the training quality of athlete, study three-dimensional optical steps sports, a action amplitude tracing process based on improved reverse kinematics is discussed. The method passes through pinhole camera, model calibrate camera imaging plane, positioning mark appears in marker point apart neighboring single-sequence and then five-point perspective same line captured straight by different positions postures. matching method’s accuracy superiority are...

10.1515/nleng-2022-0243 article EN cc-by Nonlinear Engineering 2023-01-01

With the support of big data and information technology, various sectors such as sports, health, medical industry can realize integration readjustment existing resources, which improve operation efficiency tap its huge potential. advancement in analysis, voice features, Internet Things (IoT), personalized health management is becoming development trend breakthrough sports industry. The application will out potential In this paper, we have used Mel-requency cepstrum coefficient speech feature...

10.1155/2021/3271863 article EN Scientific Programming 2021-08-26

Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation various tools to achieve desired outcomes can be labor-intensive researchers. To address this, we introduce CellAgent (http://cell.agent4science.cn/), an LLM-driven multi-agent framework, specifically designed automatic processing and execution scRNA-seq tasks, providing high-quality results with no human...

10.48550/arxiv.2407.09811 preprint EN arXiv (Cornell University) 2024-07-13

<title>Abstract</title> Pseudorabies virus (PRV) is a neurotropic herpesvirus. It not easy to tracking the whole replication progess of PRV, especially nascent viral genome in host cells. In this study, we developed dual-fluorescence-labeled PRV (rPRV-Anchor3-mCherry) with and envelope protein gM labeled by Anchor DNA labeling system mCherry, respectively. Through single-virus rPRV-Anchor3-mCherry, observed that invaded mouse neuroblastoma Neuro2a (N2a) cells <italic>via</italic> both...

10.21203/rs.3.rs-4982958/v1 preprint EN 2024-10-17

Coronavirus disease 2019 (COVID-19) vaccination regimens contribute to limiting the spread of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2). However, emergence and rapid transmission SARS-CoV-2 variant Omicron raise a concern about efficacy current strategy. Here, we expressed monomeric dimeric receptor-binding domains (RBDs) spike protein prototype in E. coli investigated reactivity anti-sera from Chinese subjects immunized with vaccines these recombinant RBDs. In 106 human...

10.3389/fimmu.2022.960195 article EN cc-by Frontiers in Immunology 2022-07-28

Objective . To observe the characteristics of ankle pain and joint muscle by microscope. Methods In a sports university, 15 athletes above grade 2 were randomly selected as experimental group, nonathletes control group. The experiment mainly included foot shape test, standard scaphoid height range motion emg other procedures. Medical microscopic image processing is new technology developed in past thirty years, which has brought great progress for mankind to understand transform nature....

10.1155/2021/2437066 article EN Journal of Sensors 2021-01-01

Background: Coronavirus disease 2019 (COVID-19) vaccination regimens contribute to limiting the spread of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2). But emergence and rapid SARS-CoV-2 variant Omicron raise concerns about efficacy current strategy. The binding activity vaccine serum virus receptor-binding domain (RBD) represents a correlation protection against infection. We here investigated reactivity anti-sera from Chinese subjects immunized with vaccines variety...

10.2139/ssrn.4074674 article EN SSRN Electronic Journal 2022-01-01

To evaluate the effect of porous nanofibre scaffold on healing and repair cartilage defects in animal models, three different PNFSs were prepared, namely gelatin/polylactic acid scaffold, thermally cross-linked Gel/PLA hyaluronic modified Gel/PLA-T scaffold. The characterisation scaffolds was implemented. Bone marrow stromal cells taken as research object, detection cell proliferation apoptosis performed to biocompatibility each after co-cultured with cells. A New Zealand rabbit model defect...

10.1504/ijnt.2022.128961 article EN International Journal of Nanotechnology 2022-01-01

Objective: The present study was carried on to assess the immunoregulatory effects of complexes obtained by any 3 polysaccharides from five kinds different edible fungi polysaccharides, including Tremella fuciformis polysaccharide, Poriacocos Lentinan, Hericium edodes polysaccharide and Dictyophora indusiata polysaccharide. Methods: Effects concentrations proliferation RAW264.7 were explored using cell counting kit (CCK)-8, levels tumor necrosis factor (TNF)-α in culture medium detected...

10.13386/j.issn1002-0306.2020110143 article EN 食品工业科技 2021-08-15
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