A5041262892- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- Mosquito-borne diseases and control
- Virus-based gene therapy research
- Animal Disease Management and Epidemiology
- Aquaculture Nutrition and Growth
- Vector-Borne Animal Diseases
- Aquaculture disease management and microbiota
- Virology and Viral Diseases
- interferon and immune responses
- Cytomegalovirus and herpesvirus research
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Animal Nutrition and Physiology
- RNA modifications and cancer
- Rabies epidemiology and control
- Viral Infectious Diseases and Gene Expression in Insects
- Adipose Tissue and Metabolism
- Plant Virus Research Studies
- CRISPR and Genetic Engineering
- Antioxidant Activity and Oxidative Stress
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
Harbin Veterinary Research Institute
2016-2025
Chinese Academy of Agricultural Sciences
2016-2025
Chinese Academy of Tropical Agricultural Sciences
2024
South Subtropical Crops Research Institute
2024
Zhejiang Chinese Medical University
2024
East China Normal University
2021-2023
Shandong Agricultural University
2023
Jilin Academy of Agricultural Sciences
2021
Shanxi Medical University
2021
Sichuan University
2021
Ferroptosis is caused by iron-dependent lipid peroxide accumulation, the sensitivity of which might be regulated acyl-CoA synthetase long chain family member 4 (ACSL4). Non-small-cell lung cancer (NSCLC) can resist oxidative stress and reduce tumor cells to ferroptosis changing expression some proteins. Mechanisms involving in NSCLC are not fully understood.A dual-luciferase reporter assay was used confirm a targeting relationship between non-coding (lnc)RNA NEAT1 ACSL4. Overexpression...
Gossypol, the main antinutritional factor in cottonseed protein concentrate (CPC), could affect growth conditions of fish, but underlying mechanism remains unclear. In this study, an 8-week feeding trial was carried out to investigate effects gossypol on Nile tilapia (Oreochromis niloticus). Three experimental diets were designed, including control diet (CON), supplemented with 150 mg/kg (ML), and 300 (MH). 16S rRNA gene sequencing showed that significantly reduced richness diversity gut...
Carbohydrates have a protein sparing effect, but long-term feeding of high-carbohydrate diet (HCD) leads to metabolic disorders due the limited utilization efficiency carbohydrates in fish. How mitigate negative effects induced by HCD is crucial for rapid development aquaculture. Uridine pyrimidine nucleoside that plays vital role regulating lipid and glucose metabolism, whether uridine can alleviate syndromes remains unknown. In this study, total 480 Nile tilapia (Oreochromis niloticus)...
African swine fever (ASF), caused by virus (ASFV), poses a great threat to the global pig industry. There is an urgent demand for effective and safe vaccines address this threat. This study reports generation evaluation of recombinant Lactococcus lactis pool, each strain expressing one eight ASFV antigens (F317L, H171R, D117L, E120R, B602L, CD2v, p54, p72). We evaluated immune responses in mice through oral gavage intramuscular immunization L. pool. The results show that immunized via...
This study investigated the effects of yellow mealworm meal (YM) replacing soybean (SBM) at different proportions (0%, 15%, 30% and 45%, referred as YM0, YM15, YM30 YM45, respectively) on flesh quality Nile tilapia. A total 360 fish (70.0 ± 0.12 g) were randomly divided into 4 groups (3 tanks per group). Fish fed experimental diet twice daily for 10 wk. The results showed that muscle protein content significantly decreased in while lipid YM45 (P < 0.05). essential amino acids flavor not...
Many host cellular signaling pathways were activated and exploited by virus infection for more efficient replication. The PI3K/Akt pathway has recently attracted considerable interest due to its role in regulating This study demonstrated the first time that mammalian reovirus strains Masked Palm Civet/China/2004 (MPC/04) Bat/China/2003 (B/03) can induce transient activation of early vitro. When UV-treated, both viruses signaling, indicating virus/receptor interaction was sufficient activate...
High level of carbohydrate in aquafeed could achieve cost-sparing effect, but it may cause adverse effects on flesh quality aquatic products. An eight-week trial was conducted to investigate whether oligosaccharides-supplementation, including Galacto-oligosaccharides (GOS) and xylo-oligosaccharide (XOS), systematically improve the growth performance, texture characteristics nutrition composition Nile tilapia fed with high-carbohydrate diet. The results indicated that GOS-supplementation...
With the development of processing technology, cottonseed protein concentrate (CPC) has been widely used as a new source to replace fish meal in aquaculture. But whether CPC can soybean still needs investigation. A ten-week experiment was designed evaluate impact replacing (SBM) with at different levels (CPC0 [0%], CPC15 [15%], CPC30 [30%], CPC45 [45%], CPC75 [75%] and CPC100 [100%]) on Nile tilapia (Oreochromis niloticus). The results showed that 45% or higher substitution significantly...
Classical swine fever (CSF), caused by the classical virus (CSFV), results in significant economic losses to industry many countries. Vaccination represents primary strategy control CSF and CSFV E2 protein is known as major protective antigen. However, expressed or presented different systems elicits distinct immune responses. In this study, we established a stable CHO cell line express delivered it using self-assembled ferritin nanoparticles (NPs). Subsequently, compared adaptive responses...
African swine fever (ASF), caused by virus (ASFV), poses a significant threat to the global industry. This underscores urgent need for safe and effective ASF vaccines. Here, we constructed five bacterium-like particles (BLPs) that each display one of ASFV antigens (F317L, H171R, D117L, B602L, p54) based on Gram-positive enhancer matrix-protein anchor (GEM-PA) system. GEM is bacterial particle contains only peptidoglycan, while PA composed three lysin motifs (Lysm) derived from C-terminus...