A5107140507- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
- Influenza Virus Research Studies
- Respiratory viral infections research
- Animal Virus Infections Studies
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- Virus-based gene therapy research
- Animal Disease Management and Epidemiology
- Mosquito-borne diseases and control
- Rabies epidemiology and control
- Vector-Borne Animal Diseases
- Immune Response and Inflammation
- Hepatitis B Virus Studies
- vaccines and immunoinformatics approaches
- COVID-19 Clinical Research Studies
- Herpesvirus Infections and Treatments
- Analytical Chemistry and Sensors
- Toxoplasma gondii Research Studies
- SARS-CoV-2 detection and testing
- interferon and immune responses
- Viral Infections and Immunology Research
- Microbial infections and disease research
- Spectroscopy Techniques in Biomedical and Chemical Research
Chinese Academy of Agricultural Sciences
2019-2025
Wuhan University of Technology
2023-2025
Jilin Academy of Agricultural Sciences
2023-2024
Tianjin University
2022-2024
Institute of Special Animal and Plant Sciences
2020-2023
University of Electronic Science and Technology of China
2022-2023
Zhengzhou University
2022-2023
Chinese Academy of Meteorological Sciences
2023
Academy of Military Medical Sciences
2012-2021
Jilin University
2013-2020
An in situ monitoring reaction can better obtain the variations during progression of photocatalytic reaction. However, complexity apparatus and limited applicability substances are common challenges faced by most methods. Here, we invented an infrared optical fiber sensor to monitor reactants products The sensor, which has four tapered regions, demonstrates best sensitivity 0.71 au/vol %, 70 times higher than that without a region. Then, this was successfully used between benzaldehyde...
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel human that can cause disease. The development of detection method for this virus lead to rapid and accurate diagnosis would be significant. In study, we established nucleic acid visualization technique combines the reverse transcription loop-mediated isothermal amplification vertical flow strip (RT-LAMP-VF) detect N gene MERS-CoV. RT-LAMP-VF assay was performed in constant temperature water bath 30 min, result visible by...
// Chong Wang 1, 2, * , Xuexing Zheng 3, 4, Weiwei Gai Yongkun Zhao 4 Hualei Haijun 2 Na Feng Hang Chi Boning Qiu Nan Li Tiecheng Yuwei Gao Songtao Yang Xianzhu Xia 1 College of Wildlife Resources, Northeast Forestry University, Harbin, China Key Laboratory Jilin Province for Zoonosis Prevention and Control, Institute Military Veterinary, Academy Medical Sciences, Changchun, 3 School Public Health, Shandong Jinan, Jiangsu Co-innovation Center Control Important Animal Infectious Diseases...
New emerging severe acute respiratory syndrome 2 (SARS-CoV-2) has caused a worldwide pandemic. Several animal models of coronavirus disease 2019 (COVID-19) have been developed and applied to antiviral research. In this study, two lethal mouse-adapted SARS-CoV-2 variants (BMA8 C57MA14) with different virulence were generated from hosts, which are characterized by high viral replication titers in the upper lower tract, pulmonary pathology, cytokine storm, cellular tropism, lymphopenia,...
Irrigation is an important means of ensuring sustainable agricultural production, and therefore critical for realizing Sustainable Development Goals. However, the persistence drought caused by climate change can deplete water resources affect irrigated crops negatively. Understanding changes in crop irrigation requirement (IWR) its meteorological driving factors thus provide key information long-term management planning. This particularly true high water-consuming arid semi-arid regions. We...
Recent successes with monoclonal antibody cocktails ZMapp(TM) and MIL77 against Ebola virus (EBOV) infections have reignited interest in antibody-based therapeutics. Since the production process for antibodies can be prolonged costly, alternative treatments should investigated. We produced purified equine antisera from horses hyperimmunized EBOV virus-like particles, tested post-exposure efficacy of a mouse model infection. BALB/c mice were given up to 2 mg per animal, at 30 minutes, 1 or...
An infrared evanescent wave sensor was developed to accurately detect ascorbic acid (vitamin C) in food and drugs. The fabricated by tapering bending of As2S3 fibers. Due the broad transmission range (5000-1500 cm-1) fibers, covering characteristic absorption peak (C = O at 1760 cm-1 C 1690 cm-1), is capable identifying detecting concentration acid. Experimental results demonstrated that a conically tapered fiber with waist diameter 50 μm, length 30 mm, radius 2 mm achieved maximum...
Marburg virus disease (MVD) is a severe infectious characterized by fever and profound hemorrhage caused the (MARV), with mortality rate reaching 90%, posing significant threat to humans. MARV lies in its classification as biosafety level four (BSL-4) pathogen, which demands stringent experimental conditions substantial funding. Therefore, accessible practical animal models are urgently needed advance prophylactic therapeutic strategies for MARV. In this study, we constructed recombinant...
Middle East respiratory syndrome coronavirus (MERS-CoV), a new that has been causing severe and fatal acute illnesses in humans since its outbreak 2012, raised public fear worldwide. The development of prophylactics therapeutics is urgently needed to prevent control MERS-CoV infections. In this study, bacterium (Lactococcus lactis)-like particle (BLP) vaccine displaying the receptor-binding domain (RBD) was developed, gram-positive enhancer matrix (GEM) particles were used as substrates...
Sini Decoction (SND), as a classic prescription of Traditional Chinese Medicine (TCM), has been proved to be clinically useful in cardiomyopathy and inflammatory bowel diseases. However, the role mechanism SND colitis-associated cancer remains unclear. This study aims evaluate effect on colorectal cancer(CRC) symptoms further explore changes gut microbes mediated by extract azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced CRC mice through 16 S rRNA sequencing. Our results indicated...
Influenza H3N8 viruses have been recovered frequently from wild bird species, including Anseriformes (primarily migratory ducks) and Charadriiformes shorebirds). However, little attention has given to the transmission ability of avian influenza among mammals. Here, we study potential human health threat molecular basis mammalian transmissibility isolated reservoirs. We classified eight into seven different genotypes based on genomic diversity. Six naturally birds acquired bind human-type...
Infrared gradient refractive index (GRIN) material lenses have attracted much attention due to their continuously varying as a function of spatial coordinates in the medium. Herein, glass accumulation thermal diffusion method was used fabricate high GRIN lens. Six Ge17.2As17.2SexTe(65−x) (x = 10.5–16) glasses with good stability and (n@10 μm > 3.1) were selected for diffusion. The span (∆n) 0.12 achieved this After diffusion, lens still had transmittance (45%) range 8–12 μm. Thermal...
Abstract H9N2 avian influenza viruses circulate worldwide in poultry and have sporadically infected humans, raising concern whether pandemic potential. Here, we use a guinea pig model to examine serial passage results adaptive viral changes that confer transmissible phenotype wild-type virus. After nine passages of an virus through pigs, productive transmission by direct contact occurred 2/3 pairs. The efficiency increased following the fifteenth 3/3 In contrast, airborne passaged was less...
Middle East respiratory syndrome (MERS) is an acute, high-mortality-rate, severe infectious disease caused by emerging MERS coronavirus (MERS-CoV) that causes diseases. The continuous spread and great pandemic potential of MERS-CoV make it necessarily important to develop effective vaccines. We previously demonstrated the application Gram-positive enhancer matrix (GEM) particles as a bacterial vector displaying receptor-binding domain (RBD) very promising vaccine candidate capable producing...
H9N2 influenza virus has been reported worldwide for several decades, and it evolved into multiple genotypes among domestic poultry. However, the study involving ecology evolution of low pathogenic avian in wild birds China is limited. Here, we carried out surveillance along with East Asian-Australian migratory flyway 2017. To estimate prevalence birds, information on exposure bird populations to viruses using serology, addition virology, would greatly improve monitoring capabilities. In...