A5101125334- Polysaccharides and Plant Cell Walls
- Glycosylation and Glycoproteins Research
- Microbial Natural Products and Biosynthesis
- Carbohydrate Chemistry and Synthesis
- Software Engineering Research
- Pharmacological Effects of Natural Compounds
- Toxin Mechanisms and Immunotoxins
- Immune Response and Inflammation
- Advanced Malware Detection Techniques
- Enzyme Production and Characterization
- Transgenic Plants and Applications
- Traditional Chinese Medicine Analysis
- Immunotherapy and Immune Responses
- Natural product bioactivities and synthesis
- Software Reliability and Analysis Research
- Microbial Metabolites in Food Biotechnology
- Parallel Computing and Optimization Techniques
- Fuzzy Logic and Control Systems
- Microbial infections and disease research
- Software Testing and Debugging Techniques
- Alkaloids: synthesis and pharmacology
- Antimicrobial Peptides and Activities
- Drug-Induced Hepatotoxicity and Protection
- Probiotics and Fermented Foods
- Bioactive natural compounds
Southwest University
2024
Academy of Military Medical Sciences
2005-2024
Shanghai University of Traditional Chinese Medicine
2016-2023
Westlake University
2023
KTH Royal Institute of Technology
2022
Institute of Pharmacology
2006-2014
Shenyang University of Chemical Technology
2012
Jingdezhen University
2010
Kailuan General Hospital
2010
Shanghai University
2006
The anti-diabetic and hypolipidemic effects of aqueous-extract from the flower Inula japonica (IJ) its two fractions (IJR IJP) were investigated in alloxan-induced diabetic mice. An oral glucose tolerance test (OGTT) IJ was also performed normal results showed that (1000 mg/kg), IJR (500 mg/kg) IJP (250 significantly reduced blood levels mice by administration (p<0.01). markedly decreased serum triglyceride concentrations (p<0.05) Their hypoglycemic activities better than gliclazide (40...
Saliva proteins may protect older people from influenza, however, it is often noted that hospitalizations and deaths after an influenza infection mainly occur in the elderly population living with chronic diseases, such as diabetes cancer. Our objective was to investigate expression level of terminal α2-3- α2-6-linked sialic acids human saliva type 2 mellitus (T2DM), liver disease gastric cancer (GC) patients assess binding activity these linked against A viruses (IAV). We observed...
Code clone detection is an important research problem that has attracted wide attention in software engineering. Many methods have been proposed for detecting code clone, among which text-based and token-based approaches are scalable but lack consideration of semantics, thus resulting the inability to detect semantic clones. Methods based on intermediate representations codes can solve detection. However, graph-based not practicable due compilation, existing tree-based limited by scale trees
Code cloning, the duplication of code fragments, is common in software development. While some reuse aids productivity, excessive cloning hurts maintainability and introduces bugs. Hence, automatic clone detection vital. Meanwhile, large language models (LLMs) possess diverse code-related knowledge, making them versatile for various engineering challenges. However, LLMs' performance unclear needs more study accurate assessment. In this paper, we provide first comprehensive evaluation LLMs...
An ultra‐performance liquid chromatography coupled with a hybrid quadrupole time‐of‐flight tandem mass spectrometry method was established to rapidly identify and guide the isolation of target saponins from fenugreek seeds. Based on online screening performance, totally forty‐six furostanol were detected elucidated. Among them, twenty compounds predicted be new. To obtain new these seeds, further phytochemical study carried out under guidance spectrometry. Finally, six saponins, named as...
Polysaccharides isolated from natural plants may represent a novel source of vaccine adjuvants. In this research, we focused on plant polysaccharide, PCP-I, which is derived Poria cocos, Chinese traditional herbal medicine. We chose the anthrax protective antigen (PA) as model to evaluate adjuvant ability PCP-I in enhancing immunogenicity and protection PA-based vaccine. According our results, could significantly enhance specific anti-PA antibodies, toxin-neutralizing antibody affinity, well...
Abstract Five new peptaibols, longibramides A–E ( 1 – 5 ) with 11 amino acid residues, were isolated from a fungus Trichoderma longibrachiatum Rifai DMG‐3‐1‐1, which was mushroom Clitocybe nebularis (Batsch) P. Kumm collected coniferous forest in the subboreal area of northeast China. The structures determined by their spectroscopic data (NMR and MS‐MS spectra), absolute configurations X‐ray diffractions Marfey's analyses. A, B, similar CD spectra showed that they all had α ‐helix...
The advancement of large language models (LLMs) has significantly propelled the field code generation. Previous work integrated reinforcement learning (RL) with compiler feedback for exploring output space LLMs to enhance generation quality. However, lengthy generated by in response complex human requirements makes RL exploration a challenge. Also, since unit tests may not cover complicated code, optimizing using these unexecuted snippets is ineffective. To tackle challenges, we introduce...
A new water-soluble hetero-polysaccharide, APSID3, was obtained from a hot-water extract of the roots Astragalus membranaceus (Fisch.) Bunge by DEAE-Sepharose Fast Flow and Sephacryl S-300 chromatography. The molecular weight APSID3 estimated to be 5.79 × 105Da. Based on sugar composition analysis, methylation partial hydrolysis 13C nuclear magnetic resonance experimentation, it concluded that minimal repeat unit composed one terminal arabinose, 1,5-linked 1,3-linked rhamnose, 1,3,4-linked...