Pablo Aguilera

ORCID: 0000-0001-7502-366X
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About
Contact & Profiles
Research Areas
  • Gut microbiota and health
  • SARS-CoV-2 and COVID-19 Research
  • Cell Adhesion Molecules Research
  • Pancreatic and Hepatic Oncology Research
  • SARS-CoV-2 detection and testing
  • Clostridium difficile and Clostridium perfringens research
  • Genomics and Phylogenetic Studies
  • Machine Learning in Bioinformatics
  • Systemic Lupus Erythematosus Research
  • Growth and nutrition in plants
  • vaccines and immunoinformatics approaches
  • Monoclonal and Polyclonal Antibodies Research
  • Legume Nitrogen Fixing Symbiosis
  • Sunflower and Safflower Cultivation
  • Celiac Disease Research and Management
  • HER2/EGFR in Cancer Research
  • Food Security and Health in Diverse Populations
  • Mycobacterium research and diagnosis
  • Inflammatory Bowel Disease
  • Helicobacter pylori-related gastroenterology studies
  • Epigenetics and DNA Methylation

National University of Luján
2020-2024

Centro Científico Tecnológico - San Juan
2024

Consejo Nacional de Investigaciones Científicas y Técnicas
2020-2022

National Agricultural Technology Institute
2020-2022

Instituto de Agrobiotecnología del Litoral
2022

ABSTRACT Breast cancer is the leading cause of deaths in women worldwide, with about 20,000 cases annually Argentina. While age, diet, and genetics are known risk factors, most breast have unknown causes, necessitating discovery new factors. The aim this study was analysis prognostic relevance oncobiome Argentinean patients. Sequencing V4 region 16S rRNA gene performed on 34 primary tumor samples, using bioinformatic statistical analyses to identify bacteria hypothetical pathways. Each...

10.1128/msphere.00597-24 article EN cc-by mSphere 2025-02-10

The epidemiological surveillance of SARS-CoV-2 by means whole-genome sequencing has revealed the emergence and co-existence multiple viral lineages or subtypes throughout world. Moreover, it been shown that several this virus display particular phenotypes, such as increased transmissibility reduced susceptibility to neutralizing antibodies, leading denomination Variants Interest (VOI) Concern (VOC). Thus, subtyping is a crucial step for pathogen. Here, we present Covidex, an open-source,...

10.1016/j.meegid.2022.105261 article EN cc-by-nc-nd Infection Genetics and Evolution 2022-02-26

The COVID-19 pandemic poses a great challenge to global public health. extraordinary daily use of household disinfectants and cleaning products, social distancing the loss everyday situations that allow contact between individuals, have direct impact on transfer microorganisms within population. Together, these changes, in addition those occur eating habits, can affect composition diversity gut microbiota. A two-time point analysis fecal microbiota 23 Metropolitan Buenos Aires (BA)...

10.3389/fmicb.2022.803121 article EN cc-by Frontiers in Microbiology 2022-03-24

Summary Covidex is an open-source, alignment-free machine learning subtyping tool for viral species. It a shiny app that allows fast and accurate classification in pre-defined clusters SARS-CoV-2 FMDV genome sequences. The user can also build its own models with the model generator. Availability cross-platform compatible, available under terms of GNU General Public License v3 ( http://www.gnu.org/licenses/gpl.txt ). via SourceForge https://sourceforge.net/projects/covidex or web application...

10.1101/2020.08.21.261347 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-08-21

The ErbB2 receptor tyrosine kinase plays a key role in mammary gland development. It forms large clusters which serve as signaling platforms for integration of extracellular information. discoidin domain (DDR) family are collagen kinases which, together with ErbB2, involved many physiological and pathological processes. Here, we investigated the interaction DDR1 receptors breast cancer cells. In contrast to beta1‐integrin, colocalizes membrane regardless their expression levels. We...

10.1002/1873-3468.14522 article EN FEBS Letters 2022-10-21

Inflammatory bowel disease (IBD) is the most common form of intestinal inflammation associated with a dysregulated immune system response to commensal microbiota in genetically susceptible host. IBD includes ulcerative colitis (UC) and Crohn's (CD), both which are remarkably heterogeneous their clinical presentation treatment. This translates into notable diagnostic challenge, especially underdeveloped countries where on rise access diagnosis or treatment not always accessible for chronic...

10.3390/microorganisms10112190 article EN cc-by Microorganisms 2022-11-04
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