A5004398865- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Healthcare cost, quality, practices
- Health Systems, Economic Evaluations, Quality of Life
- Lipoproteins and Cardiovascular Health
- Cardiovascular Function and Risk Factors
- Cardiovascular and exercise physiology
- Clinical practice guidelines implementation
- Cardiac Health and Mental Health
- Congenital Heart Disease Studies
- COVID-19 and Mental Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- COVID-19 Clinical Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Rate Variability and Autonomic Control
- Trypanosoma species research and implications
- Hemoglobinopathies and Related Disorders
- COVID-19 and healthcare impacts
- Health, Nursing, Elderly Care
- Diabetes Management and Research
- Long-Term Effects of COVID-19
- Mitochondrial Function and Pathology
- Cardiac and Coronary Surgery Techniques
- Acute Myocardial Infarction Research
Hospital Israelita Albert Einstein
2024
Instituto Nacional de Cardiologia
2023
Hospital do Coração
2014-2022
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2020
Universidade de São Paulo
2014-2019
Universidade Federal Fluminense
2014-2016
Heart failure (HF) is one of the leading causes hospitalization in adults Brazil. However, most available data limited to unicenter registries. The BREATHE registry first include a large sample hospitalized patients with decompensated HF from different regions Brazil.Describe clinical characteristics, treatment and prognosis admitted acute HF.Observational study longitudinal follow-up. eligibility criteria included older than 18 years definitive diagnosis HF, public or private hospitals....
Background Robust data comparing long COVID in hospitalized and non-hospitalized patients middle-income countries are limited. Methods A retrospective cohort study was conducted Brazil, including patients. Long diagnosed at 90-day follow-up using WHO criteria. Demographic clinical information, the depression screening scale (PHQ-2) day 30, compared between groups. If PHQ-2 score is 3 or greater, major depressive disorder likely. Logistic regression analysis identified predictors protective...
Introduction Field hospitals, following the Fangcang Shelter Hospital model, were critical during global COVID-19 pandemic to alleviate strain on overwhelmed healthcare systems. Despite their widespread adoption, concerns persist regarding efficacy and cost-effectiveness. This study aimed assess impact of Pacaembu in São Paulo, Brazil pandemic, specifically focusing lives saved associated public health costs. Methods retrospective cohort was conducted April 6 June 29. The 200-bed field...
Background Chagas cardiomyopathy (ChC) prevalence is decreasing in Brazil and medical therapies for heart failure (HF) have improved the last decade. Whether these changes modified prognosis of ChC relative to non-Chagas cardiomyopathies (NChC) remains unknown. This study evaluated temporal trends population attributable risk (PAR) 2-year mortality among patients with HF enrolled at years 2002–2004 (era 1) 2012–2014 2) a Brazilian university hospital. Methods We prospectively studied 362...
Exhaled breath acetone (EBA) has been described as a new biomarker of heart failure (HF) diagnosis. EBA concentration increases according to severity HF and is associated with poor prognosis, especially in acute decompensated HF. However, there are no data on chronic patients. The aim evaluate the role for predicting cardiac overall mortality In GENIUS-HF cohort, patients were enrolled between August 2012 December 2014. All had left ventricular ejection fraction ≤ 50%, diagnosis was...
Previous studies have shown the occurrence of actinin-3 deficiency in presence R577X polymorphism ACTN3 gene. Our hypothesis is that this deficiency, by interfering with function skeletal muscle fiber, can result a worse prognosis patients chronic heart failure.A prospective cohort study was conducted from 2002 to 2004. The eligibility criteria included diagnosis failure stage C different etiologies. We excluded all concomitant disease could be related poor prognosis. rs1815739 (R577X)...
Abstract Background Heart failure (HF) is a major public health problem with increasing prevalence worldwide. It associated high mortality and poor quality of life due to recurrent costly hospital admissions. Several studies have been conducted describe HF risk predictors in different races, countries systems. Nonetheless, understanding population-specific determinants outcomes remains great challenge. We aim evaluate 1-year survival individuals systolic heart from the GENIUS-HF cohort....
Brazil is a country with different biomes and social disparities. There are limited data available on regional differences prognosis of heart failure (HF) in the country.
Background: There are substantial opportunities to improve the quality of cardiovascular care in developing countries through implementation a program.Objective: To evaluate effect Best Practice Cardiology (BPC) program on performance measures and patient outcomes related heart failure, atrial fibrillation acute coronary syndromes subset Brazilian public hospitals.Methods: The Boas Práticas em Cardiologia was adapted from American Heart Association's (AHA) Get With Guidelines (GWTG) Program...
Objective The aim of this study is to assess the association between genetic ancestry, self-declared race and haemodynamic parameters in patients with chronic heart failure (HF). Methods Observational, cross-sectional study. Eligible participants were aged 18 80 years; ejection fraction was ≤50%. Patients underwent analysis ancestry informative markers, echocardiography impedance cardiography (ICG). Race determined by self-classification into two groups: white non-white. Genomic estimated...
Resumo Fundamento Apesar de progresso significativo na melhoria da qualidade do tratamento doenças cardiovasculares, lacunas persistem em termos falha adesão às recomendações diretrizes. Objetivo Este estudo avalia os efeitos implementação um programa adaptado Programa Get with the guidelines® American Heart Association sobre a diretrizes para síndrome coronária aguda (SCA), fibrilação atrial (FA) e insuficiência cardíaca (IC). Métodos Avaliamos dados demográficos, medidas qualidade, desfechos [...]
Studies adopting electronic medical records and genomic information are becoming widespread. Through this new modality in research, it is possible to study how genetic variants influence susceptibility towards chronic conditions can improve patient care. Our aim develop a biobank with 2,000 heart failure patients treated tertiary cardiology hospital containing data biologic samples for performing genome-wide association studies validation development of decision routines aimed at helping the...
Abstract Background: Brazil is a country with different biomes and social disparities. There are limited data available on regional differences prognosis of heart failure (HF) in the country. Objective: The Rosa dos Ventos study aims to investigate current HF outpatients reduced or mildly ejection fraction Brazil. Methods: This prospective, multicenter, observational cohort that will include older than 18 years an < 50% 30 public private centers distributed all Brazilian regions. A total...
Background: There is not a single established effective and safe intervention to prevent major perioperative vascular complications that commonly occur in the first 30 days after noncardiac surgery. Hypothesis: We evaluated feasibility of multicenter randomized controlled trial (RCT) testing effects statins. Methods: This double blind, placebo-controlled RCT short course atorvastatin 80mg before surgery, followed by 40mg 12 hours surgery then 40mg/day for 7 patients undergoing who were at...