A5031239467- Microbial Natural Products and Biosynthesis
- Fungal Biology and Applications
- Marine Sponges and Natural Products
- Phytochemistry and Biological Activities
- Natural Compound Pharmacology Studies
- Natural product bioactivities and synthesis
- Bioactive Compounds and Antitumor Agents
- Traditional and Medicinal Uses of Annonaceae
- Phytochemical compounds biological activities
- Plant Pathogens and Fungal Diseases
- Chemical synthesis and alkaloids
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Analysis
- Plant biochemistry and biosynthesis
- Bioactive natural compounds
- Microbial Metabolism and Applications
- Parkinson's Disease Mechanisms and Treatments
- Sesquiterpenes and Asteraceae Studies
- Carbohydrate Chemistry and Synthesis
- Asymmetric Synthesis and Catalysis
- Asymmetric Hydrogenation and Catalysis
- Phytochemical Studies and Bioactivities
- Membrane Separation Technologies
- Essential Oils and Antimicrobial Activity
- Advanced oxidation water treatment
Guangdong Academy of Sciences
2016-2025
Institute of Microbiology
2016-2025
Dongguan University of Technology
2024-2025
South China Botanical Garden
2015-2024
Jiangsu Institute of Metrology
2024
Suqian University
2023-2024
Harbin Institute of Technology
2019-2024
Qingdao Agricultural University
2022-2023
Chinese Academy of Sciences
2012-2023
Shenyang Normal University
2007-2023
Given the chronic inflammatory nature of Parkinson's disease (PD), T cell immunity may be important for onset. Here, we performed single-cell transcriptome and TCR sequencing, conducted integrative analyses to decode composition, function lineage relationship cells in blood cerebrospinal fluid PD. Combined expression TCR-based tracking, discovered a large population CD8+ showing continuous progression from central memory terminal effector PD patients. Additionally, identified group cytotoxic...
Abstract Rosemary ( Rosmarinus officinalis L.) is one of the most famous spice plants belonging to Lamiaceae family as a remarkably beautiful horticultural plant and economically agricultural crop. The essential oil rosemary has been enthusiastically welcome in whole world for hundreds years. Now, it wildly prevailing promising functional food additive human health. More importantly, due its significant aroma, food, nutritional value, also plays an role food/feed packaging industries. Modern...
A remarkable visible-light-promoted photoredox catalytic methodology involved with amines and eco-friendly potassium thioacids for amide formation was uncovered. This approach can mimic the natural coenzyme acetyl-CoA to selectively acylate without affecting other functional groups such as alcohols, phenols, esters, among others. The developed strategy may hold great potential a comprehensive display of biologically interesting peptide synthesis amino acid modification through diacyl...
Membrane distillation (MD) is a promising alternative approach for desalination, especially high-salinity brines. Its application has been limited by its high operational cost because of the energy consumption required hydraulic circulation and heating entire circulating feed. Localized feed Joule diminishes consumption, but potential charging on electrothermal material surface causes water splitting membrane degradation in environments. Herein, novel reverse Joule-heating air gap MD method...
Abstract Cancer immunotherapy has become one of the current research hotspots. However, deficiencies including restricted immunogenicity, insufficient antigen presentation, and low responsive rate limited their therapeutic applications. Own to small size excellent biocompatibility, carbon dots (CDs) can serve as nanovectors improve efficacy cancer immunotherapy. Herein, a tumor antigen‐based nanovaccines (GMal+B16F10‐Ag GMal+CT26‐Ag) by conjugation CDs with cell‐derived antigens (B16F10‐Ag...
Ozone (O3), as an environmentally friendly oxidant, is widely used to remove emerging pollutants and ensure the safety of water supply, whereas restricted accessibility O3 limited collision frequency between will inevitably reduce ozonation efficiency. To promote chemical reactions target pollutants, here we developed a novel gas-solid-liquid reaction interface dominated triphase system using functional hydrophobic membrane with adsorption layer distributor place where occurred. In system,...
Hydrogenation is only the beginning: alkyl groups are mildly transferred from substituted Hantzsch esters to replace nitro of olefins provide<italic>trans</italic>-olefins in moderate excellent yields.
Cytorhizins A–D, four novel polyketide heterodimers, were isolated from the endophytic fungus Cytospora rhizophorae A761. These new compounds shared an unprecedented 6/6/5/6/8 or 6/6/5/6/7 pentacyclic ring system and fused as a fascinating cagelike skeleton, embodying by polyoxygenated isopentyl unit highly structure-combined benzophenone scaffold. Their structures elucidated extensive spectroscopic analyses X-ray diffraction techniques. Moreover, 1–4 evaluated for in vitro cytotoxicity...
Eight new polyketones colletotriones A-H (1-8), along with three known ones (9-11) were isolated from Colletotrichum sp. A885. (±)-Colletotriones A-C pairs of enantiomeric xanthones, all which featured a unique oxepin-4(7H)-xanthone tricyclic skeleton. The structures these compounds elucidated using 1D and 2D NMR data, UV, IR, HRESIMS analyses. Moreover, the single-crystal X-ray diffraction experiments ECD calculations also conducted to illustrate their absolute structures. Furthermore,...
Two new tetralones, annulohyporins A (1) and B (2), along with thirteen known compounds (3–15), were isolated from the ethyl acetate extract of solid fermentation endophytic fungus Annulohypoxylon stygium A888, which was medicinal plant Aquilaria sinensis. The structures established by detailed analyses ultraviolet-visible spectroscopy (UV), infrared (IR), mass spectrometry (MS), electronic circular dichroism (ECD) calculations nuclear magnetic resonance (NMR). Bioactivity assay showed that...
Three new azaphilone derivatives, talaraculones G‐I (1‐3), along with three known analogues (4‐6), were isolated from the deep‐sea‐derived fungus Talaromyces indigoticus South China Sea. The structures of compounds identified through spectroscopic methods and confirmed by comparison data reported in literature. absolute configurations 1 3 determined using DP4+ method electronic circular dichroism (ECD) calculations. Bioactivity assays revealed that exhibited significant inhibitory activities...
Three new diketopiperazines, dichotocejpins A–C (1–3), together with eight known analogues (4–11), were isolated from the culture of deep-sea sediment derived fungus Dichotomomyces cejpii FS110. Their structures, including absolute configurations, elucidated by a combination HRESIMS, NMR, X-ray crystallography, and ECD calculations. Compounds 4–6, 10–11 showed significant cytotoxic activities against MCF-7, NCI-H460, HepG-2, SF-268 tumor cell lines. Compound 1 exhibited excellent inhibitory...
Two new pimarane-type diterpenes, scopararanes H-I (1–2), along with five known ones (3–7) were isolated from the culture broth of a marine sediment-derived fungus Eutypella sp. FS46, which was obtained South China Sea. Their structures established by extensive spectroscopic analysis. All them evaluated for their cytotoxic activities against MCF-7, NCI-H460 and SF-268 tumour cell lines. Scopararane I (2) showed moderate inhibitory activities.
Mung bean (Vigna radiata L.) seeds (MBS) contain abundant nutrients with biological activities. This study was aimed to isolate key bioactive components from MBS antioxidant and myocardial preservation A new flavonoid C-glycoside, isovitexin-6″-O-α-l-glucoside, 14 known compounds were obtained. Their structures identified by extensive 1D 2D NMR FT–ICR–MS spectroscopic analyses. The activities of these evaluated. Compounds 1–5 7–10 displayed 2,2′-azinobis (3-ethylbenzothiazoline-6-sulphonic...
Tomentosenol A (<bold>1</bold>), along with a pair of epimers, 4<italic>S</italic>-focifolidione (<bold>2</bold>) and 4<italic>R</italic>-focifolidione (<bold>3</bold>), were isolated from the leaves <italic>Rhodomyrtus tomentosa</italic>.