A5076520837- Thyroid Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Thyroid and Parathyroid Surgery
- Organ Transplantation Techniques and Outcomes
- Head and Neck Anomalies
- Liver Disease and Transplantation
- Extracellular vesicles in disease
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer, Lipids, and Metabolism
- MicroRNA in disease regulation
- Liver Disease Diagnosis and Treatment
- Biomarkers in Disease Mechanisms
- Cancer Mechanisms and Therapy
- Organ Donation and Transplantation
- Cancer, Hypoxia, and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
- Neuroendocrine Tumor Research Advances
- Thyroid Disorders and Treatments
- COVID-19 Clinical Research Studies
- Circular RNAs in diseases
- Patient-Provider Communication in Healthcare
- Monoclonal and Polyclonal Antibodies Research
- Renal Transplantation Outcomes and Treatments
- HER2/EGFR in Cancer Research
- Protein purification and stability
Sichuan University
2016-2025
West China Hospital of Sichuan University
2016-2025
State Key Laboratory of Biotherapy
2016-2022
Sun Yat-sen University
2022
Sun Yat-sen University Cancer Center
2022
Creative Commons
2020
American Thyroid Association
2020
Weatherford College
2020
National Natural Science Foundation of China
2020
Noguchi Thyroid Clinic and Hospital Foundation
2017
Lymph node metastasis (LNM) is associated with increased risk of recurrence and poor prognosis in papillary thyroid cancer (PTC). Novel non-invasive biomarkers for the prediction LNM PTC patients are still urgently needed. In this study, relationship between expression plasma exosomal microRNAs (miRNAs) was analyzed. Further, we aimed to explore if miRNAs can serve as indicators patients.A total 64 who underwent thyroidectomy neck dissection from June 2018 July West China Hospital were...
Hashimoto's thyroiditis (HT) is an organ-specific autoimmune disease characterized by lymphocyte infiltration that destroys thyrocyte cells. The aim of the present study was to elucidate role and mechanisms tissue small extracellular vesicle (sEV) microRNAs (miRNAs) in pathogenesis HT.Differentially expressed sEV miRNAs were identified between HT normal RNA sequencing testing set (n = 20). Subsequently, using quantitative real-time polymerase chain reaction (qRT‒PCR) assays logistic...
Ex vivo liver resection combined with autotransplantation is a recently introduced approach to cure end-stage hepatic alveolar echinococcosis (HAE), which considered unresectable by conventional radical due echinococcal dissemination into the crucial intrahepatic conduits and adjacent structures. This article aims discuss manipulation details propose reasonable indications for this promising technique. All patients successfully underwent no intraoperative mortality. The median weight of...
According to the Barcelona Clinic Liver Cancer (BCLC) guidelines, transarterial chemoembolization (TACE) is recommended for BCLC stage B hepatocellular carcinoma (HCC). However, an investigation of use resection needed. Therefore, we compared efficacy and safety hepatic (HR) with that TACE in treating intermediate HCC. We retrospectively enrolled 923 patients HCC who underwent (490 cases) or HR (433 cases). The baseline characteristics, postoperative recoveries, long-term overall survival...
// Jianyong Lei 1 , Jinjing Zhong 2 Ke Jiang Zhihui Li Rixiang Gong Jingqiang Zhu Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University, Chengdu 610041, Department Pathology, Correspondence to: Zhu, email: zjqdoctor@163.com Keywords: papillary, thyroid carcinoma, skip metastasis, lymph node, metastasis Received: October 13, 2016 Accepted: January 16, 2017 Published: February ABSTRACT Objective: This study was performed to investigate the frequency pattern as well...
The outbreak of COVID-19 has disrupted social order and placed a heavy burden on the healthcare system. pandemic also an unprecedented impact medical students.
For some common thyroid-related conditions with high prevalence and long follow-up times, ChatGPT can be used to respond questions. In this cross-sectional study, we assessed the ability of (version GPT-4.0) provide accurate, comprehensive, compassionate, satisfactory responses
Introduction The growing popularity of active surveillance for papillary thyroid cancer and the COVID-19 pandemic have increased surgery delay, further necessitating a reassessment link between delay survival outcomes cancer. In this study, we aim to investigate interplay among various oncological factors, socioeconomic status, surgical timing with respect Methods A total 58,378 non-metastatic patients from 2000 2018 were screened Surveillance, Epidemiology, End Results database....
Abstract Background Anaplastic thyroid cancer (ATC) is a highly lethal disease, often diagnosed with advanced locoregional and distant metastases, resulting in median survival of just 3–5 months. This study determines the stratified effectiveness baseline treatments all combinations, enabling precise prognoses prediction establishing benchmarks for therapeutic options. Methods The extracted cohort pathologically confirmed ATC patients from Surveillance, Epidemiology, End Results program....
The level of thyroidectomy-related regret in patients with clinically low-risk papillary thyroid microcarcinoma (PTMC) and the determinants decision are largely unknown. Here, we show that 319 (24.2%) those who undergo thyroidectomy 4 (3.4%) active surveillance (AS) express heightened based on validated scale (DRS) scores first online survey (P < 0.001). Multivariable analysis second for confirm postoperative lower cancer-specific quality life (QoL) (scar psychology) (75.5%) is most common...
AIM:To detect whether the up-to-seven should be used as inclusion criteria for liver transplantation hepatocellular carcinoma. METHODS:Between April 2002 and July 2008, 220 carcinoma (HCC) patients who were diagnosed with HCC underwent (LT) at our center included.These divided into three groups according to characteristics of their tumors (tumor diameter, tumor number): Milan group (Group 1), in 2) out up-toseven 3).Then, we compared long-term survival recurrence these groups. RESULTS:The...
Aim To evaluate the safety to donors of living-donor liver transplantation. Methods This study included 300 consecutive living tissue who underwent operations at our center from July 2002 December 2012. We evaluated with regard three aspects complications were recorded prospectively and stratified by grade according Clavien's classification, data compared in two stages (the first 5 years' experience (pre-January 2008) latter (post-January 2008); laboratory tests such as function blood...
Combinations of transarterial chemoembolization (TACE) and radical therapies (pretransplantation, resection radiofrequency ablation) for hepatocellular carcinoma (HCC) have been reported as controversial issues in recent years. A consecutive sample 1560 patients with Barcelona Clinic Liver Cancer (BCLC) stage A/B HCC who underwent solitary Radiofrequency ablation (RFA), or liver transplantation (LT) adjuvant pre-operative TACE were included. The 1-, 3- 5-year overall survival rates...
The multifocal papillary thyroid cancer (PTC), with more aggressive and poorer prognosis, is not rare in histotype. Few studies evaluated risk factors lymph node metastasis PTC. aim of this present study focusing on characteristics PTC was excepted to assist clinical decisions regarding surgery. It a retrospective study. 1249 consecutive patients were reviewed. Of these, 570 who met the criteria selected: 285 solitary investigated by univariate multivariate analysis. Multifocal showed higher...
The extent of metastatic lymph node (LN) invasion was not considered in the postoperative stratification recurrence risk papillary thyroid carcinoma (PTC) 2015 American Thyroid Association (ATA) guidelines, and recommended cannot be applied to individuals. A nomogram based on these factors developed predict individual risk.Data from 1788 PTC patients at West China Hospital 306 cases Shang Jin Nan Fu between August 2013 July were included this study. randomized into two groups-the training...
Background: Based on the new TNM classification, differentiated thyroid carcinomas with extrathyroidal extension (ETE) into strap muscles are designated as T3b. The current study analyzed clinical significance of this stage in patients papillary cancer (PTC). Subjects and Methods: This retrospective cohort included 4045 eligible PTC patients. were divided four groups according to extent ETE: no ETE, ETE perithyroidal tissue, T3b (ETE muscles), beyond muscles. Differences characteristics...