A5102820857- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Genetic factors in colorectal cancer
- Neuroendocrine Tumor Research Advances
- Lung Cancer Treatments and Mutations
- Cervical Cancer and HPV Research
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Acute Ischemic Stroke Management
- Thyroid Disorders and Treatments
- Salivary Gland Disorders and Functions
- Systemic Lupus Erythematosus Research
- Salivary Gland Tumors Diagnosis and Treatment
- Voice and Speech Disorders
- Phytochemistry and Bioactivity Studies
- Health Systems, Economic Evaluations, Quality of Life
- Cerebrovascular and Carotid Artery Diseases
- HER2/EGFR in Cancer Research
- Hepatitis C virus research
- Head and Neck Anomalies
- S100 Proteins and Annexins
- Multiple and Secondary Primary Cancers
- Bioinformatics and Genomic Networks
- Colorectal Cancer Treatments and Studies
- Chronic Kidney Disease and Diabetes
Peking University
2025
Peking University Cancer Hospital
2025
Zhejiang University
2020-2021
Hangzhou First People's Hospital
2019-2020
Zhejiang Chinese Medical University
2018-2020
Nanjing Medical University
2014-2015
Shanghai Chest Hospital
2014
Shanghai Jiao Tong University
2014
In breast cancer, the cancer stem cells (CSCs) are thought to be main cause of metastasis and recurrence. Targeting CSCs or with cell-like properties has become a new approach for treatment cancer. Glabridin (GLA), phytochemical from root Glycyrrhiza glabra, exhibited effective antitumor in various human cells. However, roles GLA regulation CSC-like underlying molecular mechanisms remain unclear. Here, we reported that attenuated through microRNA-148a (miR-148a)/transforming growth factor...
Background: Patients with rare cancers face substantial challenges due to limited evidence-based treatment options, resulting from sparse clinical trials. Advances in large language models (LLMs) and recommendation algorithms offer new opportunities utilize all trial information improve decisions. Methods: We used LLM systematically extract standardize more than 100,000 cancer trials ClinicalTrials.gov. Each was annotated using a customized scoring system reflecting cancer-treatment...
Cervical regional lymph node involvement (CRLNI) is common in papillary thyroid microcarcinoma (PTMC), but the way to deal with cervical of clinically negative PTMC controversial.We studied data patients histologically confirmed Surveillance, Epidemiology, and End Results (SEER) Program Department Surgical Oncology Hangzhou First People's Hospital (China).We screened 6 variables demographic clinicopathological characteristics as potential predictors further constructed a model based on...
Background: Cervical lymph node metastasis (LNM) is a prognostic factor of papillary thyroid carcinoma (PTC). The way to deal with posterior the right recurrent laryngeal nerve (LN-prRLN) controversial. Nevertheless, if metastatic nodes are not removed during first operation, subsequent salvage surgery tumor in this area would entail high risk and complication. purpose study was develop preoperative prediction model for LN-prRLN PTC patients using clinicopathological characteristics....
Current treatments for breast cancer, a common malignancy in human females, are less than satisfactory because of high rates metastasis. Glabridin (GLA), which acts through the FAK/ROS signaling pathway, has been used as an antioxidant and anti-metastatic agent. However, little is known regarding effect microRNA (miRNA) on GLA's activity. The miRNA-200 family, frequently expressed at low levels triple negative cancers, inhibits metastasis by blocking epithelial-mesenchymal transition. Here,...
Thyroid cancer (TC) is one of the most common types malignancy endocrine-system. At present, there a lack effective methods to predict neck lymph node metastasis (LNM) in TC. The present study compared expression profiles from Cancer Genome Atlas between N1M0 and N0M0 subgroups each T1-4 stages TC order identify four groups LNM-associated differentially expressed genes (DEGs). Subsequently, DEGs were combined obtain total 493 integrated by using method Robust Rank Aggregation. Furthermore,...
Objective This study summarizes the anatomical features of superior laryngeal nerve in Chinese to enable rapid location during an operation. Study Design Retrospective analysis data. Setting Hangzhou First People’s Hospital Affiliated Nanjing Medical University. Methods A total 71 embalmed human cadavers (132 heminecks) were examined over 3 months. The length and diameter internal external branches their relationships with different landmarks recorded. Results branch was 23.4 ± 6.9 mm. 47.7...
ABSTRACT Background The BRAFV600E mutations is an important molecular event in the occurrence and development of papillary thyroid carcinoma (PTC). A qualitative detection mutation still insufficient to explain biological behavior PTC. Though quantitative can reflect certain characteristics PTC, its clinical value controversial. We aimed investigate association between ratio alleles clinicopathological parameters PTC patients. Methods Genomic DNA was extracted from specimens obtained 329...