A5100442600- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Mental Health Research Topics
- Advancements in Transdermal Drug Delivery
- Neural and Behavioral Psychology Studies
- Bee Products Chemical Analysis
- Transcranial Magnetic Stimulation Studies
- Essential Oils and Antimicrobial Activity
- Aesthetic Perception and Analysis
- Muscle Physiology and Disorders
- Behavioral Health and Interventions
- Face Recognition and Perception
- Cholesterol and Lipid Metabolism
- Advanced Drug Delivery Systems
- Neurogenetic and Muscular Disorders Research
- Complex Systems and Time Series Analysis
- Genetic Neurodegenerative Diseases
- Decision-Making and Behavioral Economics
- Neurological Disorders and Treatments
- Vestibular and auditory disorders
- Neuroscience and Neuropharmacology Research
- Health, Environment, Cognitive Aging
- Liver Disease Diagnosis and Treatment
- Nanoparticle-Based Drug Delivery
- Anatomy and Medical Technology
University of Electronic Science and Technology of China
2025
BeiGene (China)
2025
Shanghai Sunshine Rehabilitation Center
2019-2025
The University of Texas at Dallas
2021-2024
Shanghai Jiao Tong University
2024
University of Chicago
2022-2023
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2021
Shanghai University of Traditional Chinese Medicine
2021
Duke University
2018-2020
Kumamoto University
2019
Older adults with lower education are at greater risk for dementia. It is unclear which brain changes lead to these outcomes. Longitudinal imaging-based measures of structure and function were examined in adult individuals (baseline age, 45-86 years; two five visits per participant over 1-9 years). College degree completion differentiates individual-based neighborhood-based socioeconomic status disadvantage. (~65 years over) without a college exhibit pattern declining large-scale functional...
Alzheimer's disease (AD) is associated with changes in large-scale functional brain network organization. Individuals AD exhibit less segregated resting-state networks compared individuals without dementia. However, declines segregation are also evident as adult grow older. Determining whether these observations reflect unique or overlapping alterations on the connectome of essential for understanding impact organization and incorporating measures toward characterization. Relationships...
Abstract Measures of functional brain network segregation and integration vary with an individual’s age, cognitive ability, health status. Based on these relationships, measures are frequently examined to study quantify large-scale patterns organization in both basic applied research settings. However, there is limited information the stability reliability as time-series; measurement properties critical understand if be used for individualized characterization networks. We examine using...
The relative timing of transcranial direct current stimulation (tDCS) and motor practice holds potential importance in modulating cortical activity facilitating behavioral performance. A single-blind, randomized, cross-over experiment was conducted. Twenty healthy participants engaged a sequential finger-tapping task with their left hand. High-definition anodal tDCS (1 mA, 20 min) administered over the right primary cortex (M1) either during (concurrent-tDCS) or before (prior-tDCS). sham...
Scope To investigate the role of endoplasmic reticulum stress (ERS)‐induced autophagy in inflammatory bowel disease (IBD) and intervention mechanism Portulaca oleracea L . (POL) extract, a medicinal herb with anti‐inflammatory, antioxidant, immune‐regulating, antitumor properties, vitro vivo. Methods Results An IL‐10‐deficient mouse model is used for vivo experiments; thapsigargin (Tg)‐stimulated ERS human colonic mucosal epithelial cells (HIECs) experiments. The levels ERS‐autophagy‐related...
Diffuse transmission is an important non-synaptic communication mode in the cerebral neocortex, which neurotransmitters released from en passant varicosities interact with surrounding cells. In a previous study we have shown that cholinergic axonal segments were microproximity dopaminergic fibers possessed greater density of compared to more distant segments, suggesting activity-dependent level zone interaction. To further evaluate this plastic relationship, was quantified on fiber within...
Abstract Background Hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN‐P) is characterized by adult onset, a slowly progressive course autosomal inheritance. It remains unclear whether myopathic changes occur histopathologically. Methods We encountered 2 patients in family heterozygous p.P285L mutation TRK‐fused gene (TFG) , which known to cause HMSN‐P. The affected individuals developed proximal‐dominant muscle weakness their 40s, progressed neuron disease‐like...
Chinese vine tea can improve glucose and lipid metabolic disorders. However, its protective effects in non-alcoholic steatohepatitis (NASH) underlying molecular mechanisms remain unclear. Liver X receptor α (LXRα) inhibition adenosine monophosphate-(AMP)-activated protein kinase (AMPK) activation enhance control of NASH. AMPK activators have also been shown to inactivate LXRα. Here, the anti-NASH extract (VTE) dosed at 1 g.100 g −1 diet were investigated using NASH mice challenged with a...
Recent research suggests that people can learn to link the control process of task switching predictive cues so switch costs are attenuated following informative precues likelihood. However, precise conditions shape such contextual cuing not well understood. Farooqui and Manly (2015) raised possibility cued is more effective when demand presented subliminally. In current study, we aimed replicate extend these findings by systematically manipulating whether consciously perceived or...
This consensus specifies the terms, definitions, requirements, and test methods for auxiliary surgical devices systems using robotic technology under high-stress conditions. expert applies to
Abstract Background Alzheimer’s disease (AD) is defined by the accumulation of Aβ plaques and tau neurofibrillary tangles. The consequences these pathologies include neurodegeneration cognitive dysfunction. However, process which AD leads to impairment remains unclear. Some individuals can harbor pathological burden yet be cognitively unimpaired; observations have led ideas about reserve (Stern, Lancet, 2012). Dominant models biomarkers do not direct measures brain function. To address this...
Abstract Background Alzheimer’s disease (AD) is defined by the accumulation of Aß plaques and tau neurofibrillary tangles. The consequences these pathologies include neurodegeneration cognitive dysfunction. However, process which AD leads to impairment remains unclear. Some individuals can harbor pathological burden yet be cognitively unimpaired; observations have led ideas about reserve (Stern, Lancet, 2012). Dominant models biomarkers do not direct measures brain function. To address this...
The visual world is always changing. While we learn from regular patterns in our environment, also surprising changes that violate beliefs, such as when objects move abruptly or people behave unpredictably. What are the brain networks predictive of surprise environment? To address this question, reanalyzed openly available fMRI data collected participants performed a task which they learned to predict location an upcoming object (N=32; McGuire et al., 2012; Kao 2020). al. (2012) developed...
Attention fluctuates between optimal and suboptimal states. How do these changes affect what we learn from our environments? In particular, they the degree to which visual regularities? This question seems nearly impossible answer: Although regularities across repeated pattern exposure, may be attentive at one exposure but inattentive next. To overcome this challenge, designed a task in are presented contingent on attentional state. an online study (N=150), participants performed continuous...