A5002315925- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Inflammatory Bowel Disease
- Liver Disease and Transplantation
- Metastasis and carcinoma case studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Microscopic Colitis
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Leech Biology and Applications
- Immune cells in cancer
- Abdominal vascular conditions and treatments
- Genetic factors in colorectal cancer
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Chemokine receptors and signaling
- Cancer Diagnosis and Treatment
- Celiac Disease Research and Management
- Organ Donation and Transplantation
- Parasite Biology and Host Interactions
- Renal Diseases and Glomerulopathies
Hiroshima University Hospital
2020-2025
Hiroshima University
2023-2024
National Hospital Organization
2017-2018
Creative Research Enterprises (United States)
2018
Kure Medical Center
2017-2018
Birmingham City University
2018
Tokushima University
2017
Endoscopic phenotypes of pouchitis according to the Chicago Classification have been reported be associated with poor pouch outcomes in ulcerative colitis (UC). Here, we aimed assess prevalence endoscopic and their predictability for outcomes. This retrospective multicenter study included UC patients aged 18 years or older who underwent total colectomy between January 2000 March 2020. The primary endpoints were frequencies chronic failure. findings evaluated at initial pouchoscopy 3 10 after...
Abstract Background and study aims Endoscopic submucosal dissection (ESD) for colorectal neoplasms remains challenging because of technical issues imposed by the complex anatomical features large intestine. We evaluated feasibility, short- long-term clinical outcomes ESD early performed using Stag-beetle Knife Jr. (SB Jr.) Patients methods retrospectively assessed 228 patients who underwent 247 lesions with SB Clinicopathological characteristics neoplasms, complications, various were...
The risk of malignant tumor progression has been a concern associated with the use anti-tumor necrosis factor-alpha monoclonal antibody (anti-TNFα mAb). On contrary, recent observational studies have reported negatively on this and instead suggested that anti-TNFα mAb acts as suppressor in inflammatory carcinogenesis models subcutaneous transplant colorectal cancer. However, no consensus established regarding actual effects tumors. Here, we aimed to evaluate, for first time, effect...
Abstract Background The validity of endoscopic submucosal dissection (ESD) for esophageal squamous cell carcinoma (ESCC) in older individuals with comorbidities remains unclear. Therefore, this study evaluated the safety and efficacy ESD additional treatment ESCC adult patients. Methods clinicopathological characteristics clinical outcomes 398 consecutive patients (≥ 65 years) 505 lesions who underwent at Hiroshima University Hospital between September 2007 December 2019 were retrospectively...
To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device.
We aimed to evaluate the usefulness and acceptability of CapsoCam Plus (CapsoCam) in Japanese patients.
The advantages of endoscopic submucosal dissection (ESD) include the ability to control resection size and shape permit en bloc large ulcerated lesions.1Saito Y. Yamada M. So E. et al.Colorectal dissection: technical compared mucosal minimally invasive surgery.Dig Endosc. 2014; 26: 52-61Crossref PubMed Scopus (62) Google Scholar However, even with ESD, treatment is challenging for post-EMR recurrence colorectal tumors because severe fibrosis.2Hayashi N. Tanaka S. Nishiyama al.Predictors...
We report a case of 59-year-old woman who was diagnosed with gastric and small intestinal anisakiasis, which successfully treated endoscopic extraction Gastrografin therapy. She admitted to our hospital epigastric pain vomiting one day after eating raw fish. exhibited tenderness in the epigastrium without obvious rebound or guarding. Computed tomography (CT) demonstrated segmental edema wall proximal dilatation number ascites. Because enteric anisakiasis suspected based on patient's history...
Serum amyloid A (SAA) is an acute phase inflammatory protein that we previously described as a robust biomarker of colorectal inflammation in patients with ulcerative colitis (UC) clinical remission. However, what induces SAA expression UC remains unclear. This study demonstrates significantly expressed the intestinal tract mouse models when compared C-reactive protein, another biomarker. Moreover, interleukin-6 and tumor necrosis factor-α were found to promote SAA1 expression, Toll-like...
Abstract Background and Aim Although small‐bowel capsule endoscopy (CE) is widely used for obscure gastrointestinal bleeding (OGIB), long‐term outcomes OGIB patients after negative CE remain unclear. Herein, we defined as P0 (no potential) or P1 (less likely to bleed), based on the P classification using CE. We aimed clarify of with Methods This single‐center observational study enrolled 461 consecutive who underwent from March 2014 October 2021 were followed up >1 year. examined...
Inflammatory bowel disease (IBD) is a chronic inflammation of the gastrointestinal tract. Some patients with this condition have been reported to present immunoglobulin A nephropathy (IgAN), renal complication that can cause end-stage failure, but frequency comorbidity has not described. Thus, aim study was investigate IgAN in IBD.This included 620 IBD (338 ulcerative colitis [UC] and 282 Crohn's [CD]) from Hiroshima University Hospital outpatient department. cases were identified medical...
A 69-year-old woman presented to our department with the chief complaint of diarrhea. She had undergone left nephrectomy for renal cancer 14 years earlier. Three earlier, metastasis was detected in retroperitoneal cavity, and pazopanib administration initiated. In 29th month after start chemotherapy, patient developed diarrhea, on 31st month, computed tomography showed thickening intestinal wall. Colonoscopy revealed white villi, intramucosal hemorrhage terminal ileum, rough inflammatory...
Abstract Background The validity of endoscopic submucosal dissection (ESD) for esophageal squamous cell carcinoma (ESCC) in elderly persons with comorbidities remains unclear. This study evaluated the safety and efficacy ESD additional treatment ESCC patients. Methods retrospectively clinicopathological characteristics clinical outcomes 398 consecutive patients (age ≥ 65 years) 505 lesions who underwent at Hiroshima University Hospital between September 2007 December 2019. Additionally,...
Portal hypertensive enteropathy (PHE) is a small-bowel lesion observed in patients with portal hypertension. The clinical significance of endoscopic findings PHE remains unclear. We aimed to clarify the and predictive factors capsule based on long-term outcomes. This retrospective study enrolled 55 (33 males 22 females; median age, 64 years; range, 23–87) followed for > 3 years using endoscopy (CE) between February 2009 May 2023. evaluated affecting exacerbations effects gastrointestinal...
Abstract Objectives Endoscopic treatment of superficial pharyngeal carcinomas includes endoscopic submucosal dissection (ESD; usually performed by endoscopists), and laryngo‐pharyngeal surgery (ELPS; primarily otolaryngologists). Few studies have compared the efficacy two techniques in treating carcinomas. In this study, we outcomes these to determine advantages. Methods We retrospectively examined short‐ long‐term 93 consecutive patients with carcinoma who either underwent an ESD or ELPS...
Background/Objectives: Colorectal neoplasia developing from ulcerative colitis mucosa (CRNUC) can be divided into colitis-associated (UCAN) and non-UCAN; however, it is often difficult to distinguish UCAN non-UCAN during a biopsy diagnosis. We investigated whether genomic analysis could improve the diagnostic accuracy of using specimens. Methods: In step 1, 14 CRNUCs were used examine landscape resection specimens matched. 2, we relationship between landscapes pathological diagnosis 26...