A5042681436- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Metastasis and carcinoma case studies
- Biliary and Gastrointestinal Fistulas
- Aortic Disease and Treatment Approaches
- Drug Transport and Resistance Mechanisms
- Colorectal Cancer Surgical Treatments
- IgG4-Related and Inflammatory Diseases
- Cardiac Valve Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Genomics and Diagnostics
- Dysphagia Assessment and Management
- Esophageal Cancer Research and Treatment
- Abdominal vascular conditions and treatments
- Aortic aneurysm repair treatments
- Cancer Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Lymphoma Diagnosis and Treatment
Kure Medical Center
2016-2025
National Hospital Organization
2015-2024
Chiba University
2024
Jichi Medical University
2017-2024
Jichi Medical University Saitama Medical Center
2017-2024
Birmingham City University
2018
Creative Research Enterprises (United States)
2018
Social Insurance Saitama Chuo Hospital
2008-2017
Saitama Medical University
2017
Hiroshima University Hospital
2015
Endoscopic ultrasound-guided tissue acquisition (EUS-TA) plays a crucial role in the diagnosis of pancreatic tumors. The present study aimed to investigate current status needle tract seeding (NTS) after EUS-TA tumors based on nationwide survey Japan.
Early diagnosis of pancreatic ductal adenocarcinoma (PDAC) is challenging but essential for improving its poor prognosis. We established a multicenter study to clarify the clinicopathological features, and propose new algorithm early PDAC. Ninety-six patients with stage 0 IA PDAC were enrolled from 13 high-volume centers. Overall, 70% asymptomatic. The serum enzyme levels abnormal in half patients. sensitivity endoscopic ultrasonography (EUS) detecting small was superior computed tomography...
BACKGROUND High-grade pancreatic intraepithelial neoplasia (PanIN) exhibits no mass and is not detected by any examination modalities. However, it can be diagnosed juice cytology from indirect findings. Most previous cases were based on findings of a focal stricture the main duct (MPD) caudal MPD dilatation subsequent using endoscopic retrograde cholangiopancreatography (ERCP). We experienced case high-grade PanIN with an unclear over 20-mm range, but without magnetic resonance (MRCP). CASE...
Abstract Background and study aims Endoscopic submucosal dissection (ESD) for colorectal neoplasms remains challenging because of technical issues imposed by the complex anatomical features large intestine. We evaluated feasibility, short- long-term clinical outcomes ESD early performed using Stag-beetle Knife Jr. (SB Jr.) Patients methods retrospectively assessed 228 patients who underwent 247 lesions with SB Clinicopathological characteristics neoplasms, complications, various were...
Hypoxic-ischemic (HI) insult in infants induces brain injury and results motor coordination impairments associated with cerebral palsy; however, preventive measures for HI preterm remain unclear. We investigated the impact of progesterone (P4) a rat model that mimics infants.
To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device.
Pathological examination is essential for the diagnosis and treatment of pancreatic ductal adenocarcinoma (PDAC). Moreover, a reliable pathological extremely important improving prognosis, especially in early-stage PDAC. This study prospectively evaluated usefulness repeated juice cytology (PJC) using an endoscopic nasopancreatic drainage (ENPD) catheter We enrolled 82 patients suspected having resectable PDAC, based on imaging studies, judged necessity cytology. The diagnostic yield up to...
Hemorrhage from pelvic fracture is a major cause of mortality after blunt trauma. Several studies have suggested that early fibrinogen supplementation improves outcomes traumatic hemorrhage. Thus, we revised our massive transfusion protocol (MTP) in April 2013 to include off-label administration concentrate. The objective this study was evaluate the impact revision on short-term patients.This single-center, retrospective, cohort study. A total 224 consecutive patients hospitalized Saitama...
Abstract Background Few reports have performed a prognostic analysis based on bioelectrical impedance in patients with radical resection of pancreatic ductal adenocarcinoma (PDAC), and its usefulness remains unclear. This study aimed to evaluate body composition changes undergoing for PDAC analyze impact prognosis. Methods The medical records were retrospectively reviewed, the parameters composition, including weight, skeletal muscle mass, fat mass (BFM), extracellular water-total water...
Meckel's diverticulum contains all layers of the small bowel wall and is usually treated by surgery [1] [2]. Inverted rare, with only two reports endoscopic resection [3] [4]. As preoperative diagnosis an inverted difficult [5], it was not diagnosed prior to in either case, consequently perforation due reported one case [3]. In current we condition preoperatively, subsequently used detachable snares prevent hemorrhage or perforation. We then safely using full-thickness double-balloon...
Steroids are the first-line drugs for induction of remission in patients with type 1 autoimmune pancreatitis (AIP), and usefulness steroid maintenance therapy to prevent relapse has recently been reported. However, even during therapy, a relatively large percentage predictive factors have not yet elucidated. The aim this study was clarify AIP therapy.The medical records 76 continued after were analyzed retrospectively. rate evaluated, risk investigated by univariate multivariate analysis...
Fibrates are commonly used lipid-lowering agents that act via PPARalpha, a member of the nuclear hormone receptor superfamily. The mechanism(s) fibrate-induced changes in hepatic canalicular membrane and bile lipids still unknown. Therefore, aim this study was to investigate influence fibrates on lipid metabolism assess hepatocellular cytoprotective effect hepatocyte membrane. Male ICR mice were fed standard chow with or without bezafibrate (100 mg/kg) for 6 days. expression transporters...
We report a case of 59-year-old woman who was diagnosed with gastric and small intestinal anisakiasis, which successfully treated endoscopic extraction Gastrografin therapy. She admitted to our hospital epigastric pain vomiting one day after eating raw fish. exhibited tenderness in the epigastrium without obvious rebound or guarding. Computed tomography (CT) demonstrated segmental edema wall proximal dilatation number ascites. Because enteric anisakiasis suspected based on patient's history...
Colonic stents are increasingly used to treat acute malignant colonic obstructions. The WallFlex and Niti-S D type the commonly self-expandable metallic available in Japan since 2012. stent has a risk of stent-related perforation because its axial force, while obstructive colitis weaker radial force. MD not only overcome these limitations but also permit delivery through highly flexible-tipped smaller-caliber colonoscopes.To compare efficacy safety newly developed stents.This single-center...
Pancreatic ductal adenocarcinoma (PDAC) is the third-leading cause of cancer-related death. Owing to its poor prognosis, new molecular biomarkers for PDAC are needed. Annexin A10 (ANXA10) a calcium-/phospholipid-binding protein belonging annexin family proteins. ANXA10 not only associated with gastric phenotypes, but also acts an independent prognostic factor in several cancers. However, role remains unknown. Therefore, we examined relationship between and prognosis PDAC. We analyzed...
In this report, we present 3 cases of malignant small bowel obstruction, treated with palliative care using endoscopic self-expandable metallic stent (SEMS) placement, the aim to identify safety and efficacy procedure.Baseline patient characteristics, procedure methods, time, technical clinical success rates, complications, outcomes were obtained.All patients had pancreatic cancer strictures.One received SEMS colonoscopy, while other 2 placement via double balloon endoscopy...
Abstract Background High postoperative mortality rates have been reported for percutaneous endoscopic gastrostomy (PEG), although guidelines recommend PEG patients anticipated inability of oral intake more than 4 weeks. Conversely, comorbidity indexes not adequately validated among who underwent PEG. We evaluated and clinical risk factors 30-day after Methods retrospectively reviewed 1,395 at our hospital from April 2008 to December 2020. used the direct introducer procedure perform compared...