A5065803960- Skin and Cellular Biology Research
- Hair Growth and Disorders
- Cancer and Skin Lesions
- Immunodeficiency and Autoimmune Disorders
- Cutaneous lymphoproliferative disorders research
- Inflammatory Bowel Disease
- Nail Diseases and Treatments
- dental development and anomalies
- Oral and Maxillofacial Pathology
- RNA regulation and disease
- Autoimmune Bullous Skin Diseases
- Vascular Tumors and Angiosarcomas
- Connective tissue disorders research
- Hedgehog Signaling Pathway Studies
- Wnt/β-catenin signaling in development and cancer
- Connexins and lens biology
- Shoulder Injury and Treatment
- Fungal Infections and Studies
- Immune Cell Function and Interaction
- Lymphoma Diagnosis and Treatment
- Genetic Syndromes and Imprinting
- Cancer-related Molecular Pathways
- Dermatology and Skin Diseases
- Nonmelanoma Skin Cancer Studies
- NF-κB Signaling Pathways
Niigata University
2012-2024
National Center For Child Health and Development
2022-2024
Hiroshima University
2024
National Hospital Organization
2018
Kure Medical Center
2018
Creative Research Enterprises (United States)
2018
Nagaoka University of Technology
2015
SKiN Health
2012
Niigata University Medical and Dental Hospital
2012
Advanced Dermatology
2011
Generalized pustular psoriasis (GPP) is a rare, potentially life threatening, and aggressive form of psoriasis, which characterized by sudden onset with repeated episodic skin inflammation leading to pustule formation. Familial GPP known be caused recessively inherited mutations in the IL36RN gene, encodes interleukin 36 receptor antagonist (IL-36Ra). In this article, we performed mutation analysis gene 14 Japanese patients GPP, identified two these analyzed. One patient was compound...
Pure hair and nail ectodermal dysplasia (PHNED) is a rare genetic disorder characterized by hypotrichosis or complete alopecia, as well dystrophy. Mutations in the type II keratin gene KRT85 HOXC13 on chromosome 12q have recently been identified families with autosomal-recessive PHNED. In present study, we analyzed consanguineous Syrian family an affected girl having alopecia dystrophy since birth. The clearly showed linkage to 12q13.13-12q14.3, which excluded gene. Sequencing of another...
Background Hypohidrotic ectodermal dysplasia (HED) is a rare condition characterized by hypotrichosis, hypohidrosis and hypodontia. A de novo heterozygous mutation in the tumour necrosis factor receptor‐associated 6 gene (TRAF6) was recently identified patient with HED, while functional consequences resulting from remained unknown. Objectives To determine mechanism which TRAF6 results HED. Methods We performed coimmunoprecipitation (co‐IP) studies to whether would affect interaction of...
<b><i>Background:</i></b> H syndrome is a rare autosomal recessive genetic disorder which involves the skin and other systemic organs caused by mutations in <i>SLC29A3</i> gene. <b><i>Objectives:</i></b> To disclose molecular basis of two Syrian families, to determine localization hENT3 human skin. <b><i>Methods:</i></b> DNA from families with was analyzed through direct sequencing, expression normal...
<i>Background:</i> Hypohidrotic ectodermal dysplasia (HED) is a rare condition characterized by hypotrichosis, hypohidrosis and hypodontia. The disease shows X-linked recessive, autosomal-dominant or autosomal-recessive inheritance trait. form of HED caused mutations in the <i>EDA</i> gene, while autosomal forms are either <i>EDAR</i> <i>EDARADD </i>genes. <i>Methods:</i> We analyzed DNA from Japanese patient with through direct...
Tie-over bolster dressing after skin grafting can prolong operative time, and cause hematoma seroma formation because of uneven pressure application. To describe the possibility discontinuing use tie-over dressing, we carried out a retrospective comparative study patients who underwent at an institution between January 2009 December 2014. We investigated compared take rate, healing period, wound infection rate for group non-tie-over group. Among 266 patients, 148 118 were included in group,...
Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed in patients younger than 6 years, is a challenge for pediatric gastroenterologists. Although there have been reports regarding VEO-IBD Western countries, those Asia are still lacking. This study aimed to investigate the clinical features of Japanese patients.Patients with between 2006 and 2019 were evaluated retrospectively. The phenotypes classified into ulcerative colitis type (UC-type) Crohn's (CD-type),...
Immunosuppressive therapies can affect the immune response to or safety of vaccination in patients with inflammatory bowel disease (IBD). The appropriateness should be assessed prior initiation IBD treatment because frequently undergo continuous immunosuppressive drugs. This consensus was developed support decision-making process regarding appropriate for pediatric and adult physicians by providing critical information according published literature expert about vaccine-preventable diseases...
We report a case of 59-year-old woman who was diagnosed with gastric and small intestinal anisakiasis, which successfully treated endoscopic extraction Gastrografin therapy. She admitted to our hospital epigastric pain vomiting one day after eating raw fish. exhibited tenderness in the epigastrium without obvious rebound or guarding. Computed tomography (CT) demonstrated segmental edema wall proximal dilatation number ascites. Because enteric anisakiasis suspected based on patient's history...