Can Yang

ORCID: 0000-0001-7645-8980
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About
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Research Areas
  • interferon and immune responses
  • Aquaculture disease management and microbiota
  • Research in Cotton Cultivation
  • Immune Response and Inflammation
  • Bacterial biofilms and quorum sensing
  • NF-κB Signaling Pathways
  • Antimicrobial Peptides and Activities
  • Plant biochemistry and biosynthesis
  • Probiotics and Fermented Foods
  • Plant Virus Research Studies
  • Lipid metabolism and biosynthesis
  • Pancreatic function and diabetes
  • Plant Gene Expression Analysis
  • Genetics and Neurodevelopmental Disorders
  • Atherosclerosis and Cardiovascular Diseases
  • Mitochondrial Function and Pathology
  • Photosynthetic Processes and Mechanisms
  • Cancer, Lipids, and Metabolism
  • Inflammasome and immune disorders
  • Nuts composition and effects
  • Plant Reproductive Biology
  • Herpesvirus Infections and Treatments
  • Plant Molecular Biology Research
  • RNA regulation and disease
  • Plant tissue culture and regeneration

Southwest University
2024

Yangzhou University
2024

University of Hong Kong
2024

Hunan Normal University
2023

Center for Excellence in Brain Science and Intelligence Technology
2023

Chinese Academy of Sciences
2023

Chongqing University of Posts and Telecommunications
2016

Kerala Veterinary and Animal Sciences University
2012

Northwest A&F University
2011

Tianjin University of Traditional Chinese Medicine
2010

Biofilms often engender persistent infections, heightened antibiotic resistance, and the recurrence of infections. Therefor, infections related to bacterial biofilms are chronic pose challenges in terms treatment. The main transcription regulatory factor, CsgD, activates csgABC-encoded curli participate composition extracellular matrix, which is an important skeleton for biofilm development enterobacteriaceae. In our previous study, a wide range natural bioactive compounds that exhibit...

10.1016/j.biopha.2024.116716 article EN Biomedicine & Pharmacotherapy 2024-05-11

Islet replacement therapy is limited by shortage of donor islet cells. Usage cells derived from porcine pancreatic stem (PSCs) currently viewed as the most promising alternative for human transplantation. However, PSCs are rare and have a finite proliferative lifespan. In this study, we isolated established an immortalized mesenchymal cell (MSC) line foetal pancreas, transfecting telomerase reverse transcriptase (hTERT) called these (iPMSCs). The iPMSCs been cultured more than 80 passages...

10.1111/j.1365-2184.2010.00714.x article EN Cell Proliferation 2010-12-29

Abstract Elucidating the mechanism of resistance to biotic and abiotic stress is great importance in cotton. In this study, a gene containing NAC domain, designated GbNAC1, was identified from Gossypium barbadense L. Homologous sequence alignment indicated that GbNAC1 belongs TERN subgroup. protein localized cell nucleus. expressed roots, stems, leaves, especially highly vascular bundles. Functional analysis showed cotton Verticillium wilt reduced when silenced using virus-induced silencing...

10.1534/g3.116.034512 article EN cc-by G3 Genes Genomes Genetics 2016-12-01

The toll‐like receptor 7 ( tlr7 ) gene was identified and characterized from grass carp Ctenopharyngodon idella (designated as citlr7 ), the messenger (m)RNA expression profiles were examined in vivo vitro . genomic sequence consists of 4276 nucleotides (nts), including two exons one intron. full length complementary (c)DNA is 3354 nts with longest open reading frame (ORF) 3156 encoding a peptide 1051 amino acids. mRNA high spleen, skin heart, low hepatopancreas, muscle, head kidney trunk...

10.1111/j.1095-8649.2012.03316.x article EN Journal of Fish Biology 2012-06-01

The Toll‐like receptor (TLR) family is an evolutionarily conserved component of the innate immune system that responds to specific pathogen‐associated molecular patterns (PAMP) during infections. TLR3 a putative pattern recognition (PRR) for dsRNA, common by‐product viral replication. This study reports identification and characterization full‐length orthologue (CcTLR3) in carp Cyprinus carpio . It 2899 base pairs (bp) encoding 904 amino acid residues with calculated mass 102 744 Da...

10.1111/j.1095-8649.2010.02624.x article EN Journal of Fish Biology 2010-05-01

Abstract The architecture of the cotton plant, including fruit branch formation and flowering pattern, is most important characteristic that directly influences light exploitation, yield cost planting. Nulliplex a useful phenotype to study architecture. We used RNA sequencing obtain mRNA miRNA profiles from nulliplex- normal-branch at three developmental stages. differentially expressed genes (DEGs) miRNAs were identified preferentially/specifically in pre-squaring stage, which key stage...

10.1038/srep23212 article EN cc-by Scientific Reports 2016-03-17

A full-length MyD88 cDNA (CiMyD88) was cloned and characterized from grass carp Ctenopharyngodon idella. CiMyD88 found to be broadly expressed up-regulated by reovirus (GCRV) transcripts in vitro were rapidly elevated C. idella kidney (CIK) cells after challenge with poly(I:C). These results suggest that may involved the antiviral immune defence

10.1111/j.1095-8649.2011.02910.x article EN Journal of Fish Biology 2011-03-01

Abstract Escherichia coli ( E. ) has high antimicrobial resistance and is globally prevalent, forming aggressive dense bacterial biofilms. Previous studies have shown that the mouse peptide CRAMP-34 eradicates The current study aimed to investigate mechanism of on biofilm a clinically isolated No. Ec032) with strong formation ability. An unreported gene kduD associated Ec032 was identified by transposon mutation technology, deletion strain Ec032Δ constructed using CRISPR/Cas9. Furthermore,...

10.21203/rs.3.rs-3836308/v1 preprint EN cc-by Research Square (Research Square) 2024-01-17

Abstract Subcellular Spatial Transcriptomics (SST) represents an innovative technology enabling researchers to investigate gene expression at the subcellular level within tissues. To comprehend spatial architecture of a given tissue, cell segmentation plays crucial role in attributing measured transcripts individual cells. However, existing methods for SST datasets still face challenges accurately distinguishing boundaries due varying characteristics technologies. In this study, we propose...

10.1101/2024.07.08.601384 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-07-08

<h3>Background</h3> Si Miao Yong An decoction and its medicine Mailuoning injection are proved-effect treating ischaemic cardiovascular disease, but whether it can stabilise the atherosclerotic plaque is currently no clear conclusions. We want to explore role of interventing on rabbit aortic instability. <h3>Methods</h3> Japanese white rabbits were divided into control group, model Simvastatin group group. The animals killed at end experiment. pathological changes in was observed by HE...

10.1136/hrt.2010.208967.211 article EN Heart 2010-10-01
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