A5116453039- Food composition and properties
- Celiac Disease Research and Management
- interferon and immune responses
- Microbial Metabolites in Food Biotechnology
- RNA regulation and disease
- Phytochemistry and Biological Activities
- Nanoparticle-Based Drug Delivery
- Natural product bioactivities and synthesis
- Inflammasome and immune disorders
- Food Allergy and Anaphylaxis Research
- Advanced Glycation End Products research
- Polysaccharides Composition and Applications
- Advanced oxidation water treatment
- Polysaccharides and Plant Cell Walls
- Allergic Rhinitis and Sensitization
- RNA Interference and Gene Delivery
- Sesame and Sesamin Research
- Nanomaterials for catalytic reactions
- Traditional Chinese Medicine Analysis
- Soybean genetics and cultivation
- Environmental remediation with nanomaterials
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Photocatalysis Techniques
- Acute Kidney Injury Research
- Phytase and its Applications
State Key Laboratory of Food Science and Technology
2022-2025
Nanchang University
2011-2025
Hebei Medical University
2018-2025
Second Hospital of Hebei Medical University
2018-2025
Harbin Institute of Technology
2022-2024
Chinese Academy of Agricultural Sciences
2023-2024
Institute of Food Science and Technology
2023-2024
Hunan Children's Hospital
2024
Shandong Agricultural University
2019-2023
Henan University of Technology
2021-2023
Understanding the toxicity of silica nanoparticles (SiO(2)) on cellular level is crucial for rational design these nanomaterials biomedical applications. Herein, we explore impacts geometry, porosity, and surface charge SiO(2) hemolytic activity. Nonporous Stöber nanospheres (115 nm diameter), mesoporous (120 diameter, aspect ratio 1), nanorods with 2, 4, 8 (width by length 80 × 200 nm, 150 600 130 1000 nm), their cationic counterparts were evaluated macrophages, lung carcinoma cells, human...
Silica nanoparticles (SiO2) are widely used in biomedical applications such as drug delivery, cell tracking, and gene transfection. The capability to control the geometry, porosity, surface characteristics of SiO2 further provides new opportunities for their nanomedicine. Concerns however remain about potential toxic effects upon exposure biological systems. In present study, acute toxicity systematically varied was evaluated immune-competent mice when administered intravenously. Results...
The influence of size, surface charge and functionality poly(amido amine) dendrimers silica nanoparticles (SNPs) on their toxicity was studied in immunocompetent mice. After systematic characterization nanoparticles, they were administered to CD-1 (caesarean derived-1) mice evaluate acute toxicity. A distinct trend nanotoxicity based functional group observed with regardless size. Amine-terminated fatal at doses >10 mg/kg causing haematological complications such as disseminated...
Irradiation is extensively utilized in food processing as an effective and convenient method. At present, numerous studies have investigated the potential of irradiation to reduce allergenicity. The objective this study was investigate effects treatment on structure allergenicity liquid solid sesame proteins. Sesame protein extracts lyophilized powders were irradiated at doses 0, 2.5, 5, 7.5, 10 kGy, respectively. proteins by CD spectroscopy, fluorescence indirect competitive ELISA, western...
Methionine restriction has received some attention in recent years as a novel mode of dietary intervention. Our previous study found that methionine could inhibit the celiac toxic effects of...
It has been reported that circHIPK3 can be downregulated by high glucose, suggesting its potential involvement in diabetes and diabetic complications. This study aimed to explore the role of cardiomyopathy (DC). PTEN is a kind tumor suppressor gene, which very commonly lost human cancer. We detected expression plasma samples from DC patients, patients without complications mellitus (DM) health controls RT-qPCR ELISA. In vitro cell experiment, AC16 cells (cardiomyocytes) were treated with...
Traditional thermal processing of cashews not only results in nutrient loss and harmful by-products, but also does significantly reduce allergenicity. Irradiation could be an important non-thermal method to cashew allergens' allergenicity retain their nutritional properties. This study aimed evaluate the effects gamma irradiation on structure potential Ana o 3. The 3 solutions were gamma-irradiated at 0, 1, 3, 5, 10 kGy. change was monitored by Tricine-SDS-PAGE, circular dichroism...
Abstract TRIM27 (tripartite motif‐containing 27) is a member of the TRIM motif) protein family and participates in variety biological processes. Some research has reported that was highly expressed certain kinds carcinoma cells tissues played an important role proliferation cells. However, whether takes part progression lupus nephritis (LN) especially remains unclear. Our study revealed overexpression observed kidneys patients with LN, mice mesangial exposed to LN plasma which correlated ECM...
Three doses of (+)-usnic acid (100, 200, and 240 mg/kg per d) were administered orally to Wistar rats for 8 days, metabonomic characterization acid-induced liver injury based on gas chromatography–mass spectrometry metabolic profiles was evaluated. Serum biochemical analysis histopathological examinations simultaneously performed. The liver/body weight ratio significantly increased in acid-treated groups, whereas serum alanine aminotransferase total bilirubin elevated. In sections 200 dosage...