A5112911464- Occupational Health and Performance
- Muscle metabolism and nutrition
- Bone health and osteoporosis research
- Sports Performance and Training
- Genetics and Physical Performance
- Menstrual Health and Disorders
- Exercise and Physiological Responses
- Muscle Physiology and Disorders
- Sports injuries and prevention
- Mesenchymal stem cell research
- Pregnancy-related medical research
- Adipokines, Inflammation, and Metabolic Diseases
- Pharmaceutical studies and practices
- Body Composition Measurement Techniques
- Lower Extremity Biomechanics and Pathologies
- Eating Disorders and Behaviors
- Physical Education and Training Studies
- Vitamin D Research Studies
- Workplace Health and Well-being
- Health and Wellbeing Research
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Inflammatory Bowel Disease
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Biosimilars and Bioanalytical Methods
Battle Hospital
2022-2025
Royal British Legion
2024
University of Illinois Urbana-Champaign
2019
Ithaka Harbors
2018
Loughborough University
2013
Abstract Calcium supplementation before exercise attenuates the decrease in serum calcium and increase PTH bone resorption. This study investigated effect of on metabolism during load carriage women. Forty-eight women completed two sessions (load 1 n = 48; 2 40) (12.8 km 120 min carrying 20 kg) 60 after consuming either 1000 mg (Calcium) or nothing (Control) a randomised order. Pre- post-exercise urine samples were analysed for isotope ratio (δ44/42Ca). Fasted blood taken (pre-exercise), (0,...
Unaccustomed resistance exercise can initiate skeletal muscle remodeling and adaptive mechanisms that confer protection from damage enhanced strength with subsequent stimulation. The myofiber may provide the primary origin for adaptation, yet multiple mononuclear cell types within surrounding connective tissue also contribute. purpose of this study was to evaluate acute response muscle-resident interstitial cells contraction initiated by electrical stimulation (e-stim) subsequently determine...
Hormonal contraceptive use might impair bone health and increase the risk of stress fracture by decreasing endogenous oestrogen production, a central regulator metabolism. This cross-sectional study investigated density biochemical markers metabolism in women taking hormonal contraceptives on entry to basic military training.Forty-five female British Army recruits had metabolism, areal mineral (aBMD) tibial speed sound (tSOS) measured at start training. Participants were compared their...
This study aimed to investigate associations between menstrual function, eating disorders, and risk of low energy availability with musculoskeletal injuries in British servicewomen.All women younger than 45 yr the UK Armed Forces were invited complete a survey about behaviors, exercise injury history.A total 3022 participated; 2% had bone stress last 12 months, 20% ever injury, 40% time-loss 11% medically downgraded for injury. Menstrual disturbances (oligomenorrhea/amenorrhea, history...
Abstract This study investigated sex differences in Fe status, and associations between status endurance musculoskeletal outcomes, military training. In total, 2277 British Army trainees (581 women) participated. markers performance (2·4 km run) were measured at the start (week 1) end 13) of Whole-body areal body mineral density (aBMD) bone metabolism week 1. Injuries during training recorded. Training decreased Hb men women (mean change (–0·1 (95 % CI –0·2, –0·0) –0·7 –0·9, –0·6) g/dl, both...
This study investigated sex differences in, and the effect of protein supplementation on, bone metabolism during a 36-h military field exercise. Forty-four British Army Officer cadets (14 women) completed Participants consumed either their habitual diet [n = 14 women (Women) n 15 men (Men Controls)] or with an additional 46.6 g·day-1 for Protein)]. Women Men Protein were compared Controls to examine supplementation. Circulating markers measured before, 24 h after (postexercise), 96...
Female athletes are at increased risk of menstrual disturbances. The prevalence disturbances in British Servicewomen and the associated factors is unknown. All women under 45 years UK Armed Forces were invited to complete a survey about demographics, function, eating exercise behaviors, psychological well-being. 3,022 participated; 18% had oligomenorrhoea or amenorrhoea last 12 months, 25% history amenorrhoea, 14% delayed menarche. Women who sleep ≥ 8 h lower than ≤ 5 [odds ratio (95%...
ABSTRACT Purpose: To investigate associations between hormonal contraceptive use and physical performance, body composition, musculoskeletal injuries in basic military training. Methods: Female British Army recruits (n = 450) were grouped as non-users 182), combined oral users (COCP; n 184), or progestin-only (POC; 144). Physical performance (2.4 km run, lift strength, leg power), iron vitamin D status, bone metabolism measured at the start (week 1) end 13) of Lower recorded from medical...
Military field exercises are characterised by high volumes of exercise and prolonged periods load carriage. Exercise can decrease circulating serum calcium increase parathyroid hormone bone resorption. These disturbances to metabolism be attenuated with supplementation immediately before exercise. This randomised crossover trial will investigate the effect on metabolism, mineral balance, during carriage in women.
Female athletes are at risk of menstrual disturbances as a result low energy availability, described in the Athlete Triad framework. Military roles can be physically and psychologically demanding, intake may not always match high total expenditures. High exercise volumes with insufficient intake, psychological stress, poor sleep all potential factors for disturbed function Servicewomen. PURPOSE: To determine prevalence (oligomenorrhoea or amenorrhoea history amenorrhoea) British Servicewomen...
Many military roles are physically and psychologically demanding. Energy intake may not always match high total energy expenditures Servicewomen be at risk of outcomes associated with Relative Deficiency in Sport. PURPOSE: To determine the association between menstrual function, disordered eating behaviours, low availability bone stress musculoskeletal injuries British Servicewomen. METHODS: All women <45 years UK Armed Forces were invited to complete a survey validated questionnaires...
ABSTRACT Purpose Servicewomen are at increased risk of common mental disorders compared with servicemen and their female civilian counterparts. The prevalence eating disorder disorders, associated factors in British servicewomen poorly understood. Methods All women younger than 45 yr the UK Armed Forces were invited to complete a survey about demographics, exercise behaviors, disorders. Results A total 3022 participated; 13% participants high an based on Brief Eating Disorder Athletes...
Crohn’s disease (CD) and ulcerative colitis (UC) often require life-long treatment (Tx). In Germany, approved biologic Tx includes vedolizumab (VDZ), a monoclonal anti-integrin antibody, anti-TNFα; however, real-world comparative drug costs are poorly understood. A chart review study conducted June 2016 in Germany (15 sites), included UC CD patients (patients) who were naïve (bio-naïve) or received one prior anti-TNFα initiated VDZ (infliximab-originator [IFX-O] biosimilar [IFX-B],...
Military personnel are often exposed to arduous exercise and energy deficits. Acute severe periods of deficit increase bone resorption decrease formation. Evidence for the effect on metabolism in military is limited, sex differences these responses unknown. PURPOSE: To investigate during an field exercise. METHODS: Twenty-seven British Army Officer cadets (women [n = 14]: 23 ± 1 y, 1.67 0.67 m, 61.6 6.6 kg; men 13]: 2 1.81 0.62 81.5 7.1 kg) completed a covering 70 km over undulating terrain...
PURPOSE: Military training can result in negative energy balance, low availability (≤ 30 kcal·kg FFM-1·d-1), protein balance and muscle damage. This study investigated the effect of a high dietary supplement on ad libitum macronutrient intake, function soreness, during an arduous military field exercise. METHODS: Thirty male British Army Officer Cadets were randomly assigned to control (CON; n = 15, mean ± SD; age 23 2 y, body mass 80.8 6.6 kg) or supplementation group (SUP; 25 3 84.4 12.5...
Arduous exercise in low energy availability, characteristic of military field exercise, is associated with altered endocrine function and impaired bone health. Endocrine disturbances can recover re-feeding following but the influence targeted interventions such as protein supplementation on metabolism during deficit unclear. PURPOSE: To investigate effect a high-protein dietary supplement biochemical markers resorption formation an arduous exercise. METHODS: Twenty-eight male British Army...