I‐Ju Tsai

ORCID: 0000-0001-7688-3012
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About
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Research Areas
  • Migraine and Headache Studies
  • Endometriosis Research and Treatment
  • Air Quality and Health Impacts
  • Opioid Use Disorder Treatment
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Health, Environment, Cognitive Aging
  • Uterine Myomas and Treatments
  • Menopause: Health Impacts and Treatments
  • Ophthalmology and Eye Disorders
  • Circadian rhythm and melatonin
  • Gestational Diabetes Research and Management
  • Schizophrenia research and treatment
  • Maternal Mental Health During Pregnancy and Postpartum
  • Biochemical effects in animals
  • Multiple Sclerosis Research Studies
  • Metabolism, Diabetes, and Cancer
  • Diabetes Treatment and Management
  • Bariatric Surgery and Outcomes
  • Dialysis and Renal Disease Management
  • Bipolar Disorder and Treatment
  • Pregnancy and preeclampsia studies
  • Herpesvirus Infections and Treatments
  • Peripheral Neuropathies and Disorders
  • Ophthalmology and Visual Impairment Studies

China Medical University Hospital
2014-2025

China Medical University
2014-2025

National Chung Hsing University
2024-2025

Kuang Tien General Hospital
2021-2025

National Taiwan University Hospital
2014-2021

China Medical University
2018-2021

Ministry of Health and Welfare
2020

National Taiwan University
2014

Changhua Christian Hospital
2013

Wan Fang Hospital
2011

Purpose: Schizophrenia and epilepsy may share a mutual susceptibility. This study examined the bidirectional relation between two disorders. Methods: We used claims data obtained from Taiwan National Health Insurance database to conduct retrospective cohort analyses. Analysis 1 compared 5,195 patients with incident schizophrenia diagnosed in 1999–2008 20,776 controls without disease randomly selected during same period, frequency matched sex age. 2 comprised similar method compare 11,527...

10.1111/j.1528-1167.2011.03268.x article EN Epilepsia 2011-09-19

Omega-3 polyunsaturated fatty acids (PUFAs) may benefit migraine improvement, though prior studies are inconclusive. This study evaluated the effect of eicosapentaenoic acid (EPA) on episodic (EM) prevention. Seventy individuals with EM participated in a 12-week randomized, double-blind, placebo-controlled trial from March 2020 and May 2022. They were randomly assigned to either EPA (N = 35, 2 g fish oil 1.8 mg as stand-alone treatment daily), or placebo group soybean daily). Migraine...

10.1016/j.bbi.2024.03.019 article EN cc-by Brain Behavior and Immunity 2024-03-16

Background and Purpose— Previous studies have shown regional temporal variations in epidemiological features of moyamoya disease, but population-based regions other than Japan are limited. We investigated the incidence patients characteristics disease during 12 years Taiwan using claims databases a universal health insurance system. Methods— From inpatient National Health Insurance program, we identified subjects who had an initial hospitalization with been underwent cerebral angiography as...

10.1161/strokeaha.113.004160 article EN Stroke 2014-03-28

Objective ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) is a drug transporter protein expressed on the epithelial cells of intestine and endothelial blood–brain barrier. Intestinal ABCB1 actively transports drugs from cell membrane prevents them entering blood stream whereas barrier central nervous system. In this study, we tested whether genetic polymorphisms within gene are associated with severity depression effectiveness antidepressant, escitalopram (S-CIT), in treating...

10.1097/fpc.0b013e32833db216 article EN Pharmacogenetics and Genomics 2010-09-21

Women with polycystic ovary syndrome are characterized by obesity, menstruation irregularity, hirsutism and infertility, prevalent cardiometabolic comorbidities, but population-based studies on the risk of developing coronary artery disease limited. From claims data Taiwan National Health Insurance, we identified 8048 women aged 15-49 years newly diagnosed in 1998-2013, 32192 without CAD as controls, frequency matched age diagnosis date. By end 2013, after a mean follow-up period 5.9 years,...

10.18632/oncotarget.23985 article EN Oncotarget 2018-01-04
I.-Kuan Wang Chung-Hsiang Liu Tzung‐Hai Yen Jiann‐Shing Jeng Sheng‐Feng Sung and 95 more Pai-Hao Huang Jie-Yuan Li Yu Sun Cheng‐Yu Wei Li-Ming Lien I‐Ju Tsai Fung-Chang Sung Chung Y. Hsu Chung‐Hsiang Liu Chon‐Haw Tsai Wei-Shih Huang C.‐H. Lu Tzung-Chang Tsai Chun‐Hung Tseng Kang-Hsu Lin Woei-Cherng Shyu Yu-Wan Yang Yen‐Liang Liu Der‐Yang Cho Chun-Chung Chen Jiann‐Shing Jeng Sung‐Chun Tang Li‐Kai Tsai Shin‐Joe Yeh Chih‐Hao Chen Hsin-Hsi Tsai Jieyuan Li Han‐Jung Chen Kan Lu Shih‐Pin Hsu Hung-Chang Kuo Jung-Chi Tsou Yantang Wang Yi‐Cheng Tai Meng‐Tsang Hsieh Po-Chao Liliang Cheng‐Loong Liang Hao‐Kuang Wang Yu-Tun Tsai Kuo‐Wei Wang Jui‐Sheng Chen Po‐Lin Chen Yi‐Ching Wang Chih‐Hung Chen Pi‐Shan Sung Han-Chieh Hsieh Hui‐Chen Su Hou‐Chang Chiu Li‐Ming Lien Wei‐Hung Chen Chyi‐Huey Bai Tzu-Hsuan Huang Chi Ieong Lau Ya-Ying Wu Hsu‐Ling Yeh Anna Marie Chang Ching‐Huang Lin Cheng-Chang Yen Ruey‐Tay Lin Chun‐Hung Chen Gim‐Thean Khor A‐Ching Chao Hsiu‐Fen Lin Poyin Huang Huey‐Juan Lin Der-Shin Ke Chia‐Yu Chang Poh‐Shiow Yeh Kao‐Chang Lin Tain‐Junn Cheng Chih‐Ho Chou Chun-Ming Yang Hsiu-Chu Shen An‐Chih Chen Shih-Jei Tsai Tsong‐Ming Lu Sheng-Ling Kung Mei-Ju Lee Hsi-Hsien Chou Wei‐Lun Chang Pai‐Yi Chiu Min‐Hsien Hsu Po‐Chi Chan Chau-Hsiung Pan Hai-Ming Shoung Yi‐Chen Lo Fu-Hwa Wang Wei‐Chieh Chang Ta‐Chang Lai Jiu‐Haw Yin Chung-Jen Wang Kaichen Wang Li-Mei Chen Jong-Chyou Denq Yu Sun

10.1016/j.atherosclerosis.2017.11.029 article EN Atherosclerosis 2017-12-11

Hysterectomy has been associated with metabolic change and cardiovascular risk for women after removing the uterus, but inconclusive. This large retrospective cohort study evaluated hyperlipidemia a hysterectomy and/or oophorectomy. From claims data of one million people in National Health Insurance (NHI) database Taiwan, we established consisting 5887 newly received surgery from 2000-2013, 563 had oophorectomy, 556 data, 28024 without any surgeries were identified to form comparison cohort,...

10.1038/s41598-018-31347-z article EN cc-by Scientific Reports 2018-08-22

Aim: Paroxetine is a drug of choice in the treatment major depressive disorder (MDD). Its metabolism has recently been reported to be mediated through CYP enzymes 1A2 and 2D6. In our current study, we tested whether genetic polymorphisms CYP1A2 are associated with efficacy side effects paroxetine. Materials & methods: A total 241 MDD patients who had taken paroxetine continually for 8 weeks were recruited, their steady state concentrations measured at 2, 4 8. The genotypes these then...

10.2217/pgs.10.128 article EN Pharmacogenomics 2010-11-01

<b><i>Background:</i></b> The effect of different renal replacement therapies on the risk developing herpes zoster in failure patients is unknown. We aimed to investigate incidence attack among who were receiving dialysis modalities, transplantation (RT), or not any above mentioned yet. <b><i>Methods:</i></b> A retrospective cohort study national health insurance register database was conducted. This observational involved 79,581 controls,...

10.1159/000339004 article EN American Journal of Nephrology 2012-01-01

Background and Purpose— The study aimed to assess whether onset headache is an ominous sign in patients with first-ever ischemic stroke. Methods— A large population of stroke was obtained from the Taiwan Stroke Registry. subtypes were classified by Trial ORG 10172 Acute Treatment (TOAST) criteria. On basis International Classification Headache Disorders, second version, defined as a new that developed at Clinical features impact on outcomes, including in-hospital evolution, changes National...

10.1161/strokeaha.113.677070 article EN Stroke 2013-05-24

Migraine is linked to endothelial dysfunction and considered be a systemic vasculopathy. Interestingly, vascular diseases also occur in glaucoma patients are risk factors. Whether migraine simply concomitant condition or factor per se for remains unknown. Thus, the present study, we investigated open angle (OAG) migraineurs using 10-year follow-up study that employed nationwide population-based dataset Taiwan.This retrospective matched-cohort used data sourced from Longitudinal Health...

10.1186/s12886-019-1062-9 article EN cc-by BMC Ophthalmology 2019-02-13

Background and Purpose- The observation that smokers with stroke could have better outcome than nonsmokers led to the term "smoking paradox." controversy of such a complex claim has not been fully settled, even though different case mix was noted. Analyses were conducted on 2 independent data sets evaluate determine whether paradox truly exists. Methods- Taiwan Stroke Registry 88 925 cases, MJ cohort 541 047 adults participating in medical screening program 1630 deaths developed during 15...

10.1161/strokeaha.119.027012 article EN Stroke 2020-03-18

Migraine is a common disabling disorder, and its substantial burden associated with considerable negative impact on the patients' quality of life. Moreover, aging patients migraine have more cognitive complaints. Additionally, elderly are likely to sleep disturbances, which may also predict risk incident dementia. Migraines reported be closely circadian rhythms. Sleep disturbance well-known trigger for episodes; moreover, shift work or jet lag reportedly triggers some migraines. The...

10.3389/fnagi.2022.1041076 article EN cc-by Frontiers in Aging Neuroscience 2023-01-19

Background: Although aromatherapy is considered an adjuvant therapy to promote sleep quality, few objective testing instruments can confirm the effects of on physiology. The purpose this study was and compare immediate a single lavender essential oil (SLEO) group complex (CLEO) by polysomnography (PSG) recordings. Methods: Participants were randomly divided into SLEO CLEO in single-blind trial explore effect aroma. All participants completed sleep-related questionnaires underwent two...

10.1097/jcma.0000000000000932 article EN cc-by-nc-nd Journal of the Chinese Medical Association 2023-04-25

Abstract We explored whether hysterectomy with or without bilateral oophorectomy was associated the increasing incidence of diabetes mellitus (DM) in an East Asian population. This a retrospective population-based cohort study that analyzed DM risk Taiwanese women, using health insurance research database 1998 to 2013 containing nearly 1 million people. identified 7088 women aged 30 49 years who had undergone oophorectomy. The comparison group included 27,845 were randomly selected from...

10.1097/md.0000000000024468 article EN cc-by-nc Medicine 2021-01-29

Hysterectomy is a common procedure for benign pathologies of the uterus. Reduced production estrogen following hysterectomy has been reported. Yet association between and coronary artery disease (CAD) risk remains controversial. The aim this study was to investigate effect on CAD; calculations were adjusted traditional factors. This used 1 million patient cohort Taiwan National Health Insurance database included total 7331 women who received from 2000 2013. We randomly selected control group...

10.1097/md.0000000000010421 article EN cc-by-nc Medicine 2018-04-01
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