- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- BRCA gene mutations in cancer
- Homelessness and Social Issues
- Adolescent Sexual and Reproductive Health
- Pharmacogenetics and Drug Metabolism
- Telemedicine and Telehealth Implementation
- Mobile Health and mHealth Applications
- Chronic Disease Management Strategies
- HIV/AIDS Research and Interventions
- Child and Adolescent Health
- Global Health Care Issues
- Reading and Literacy Development
- Childhood Cancer Survivors' Quality of Life
- HER2/EGFR in Cancer Research
- School Health and Nursing Education
- Peptidase Inhibition and Analysis
- HIV, Drug Use, Sexual Risk
- Food Security and Health in Diverse Populations
- Family and Disability Support Research
- Emergency and Acute Care Studies
- Venous Thromboembolism Diagnosis and Management
- Adolescent and Pediatric Healthcare
- COVID-19 and Mental Health
- Psychological Well-being and Life Satisfaction
University of Liverpool
2015-2025
National Institute for Health Research
2018-2025
Oregon Health & Science University
2023
Gold Coast Hospital
2022
NIHR Collaboration for Leadership in Applied Health Research and Care North West Coast
2019
Seton Healthcare Family
2012
University of Manchester
2011-2012
Manchester Academic Health Science Centre
2012
Liverpool John Moores University
2006-2011
Royal Manchester Children's Hospital
2010
In many countries age at pubertal onset has declined substantially. Relatively little attention been paid to how this decline may affect adolescent behaviours such as substance use, violence and unprotected sex consequently impact on public health. the UK, two opportunistic samples (aged 16-45 years), paper-based (n = 976) online 1117), examined factors associated with earlier whether of predicted sexual risk-taking, use anti-social during early adolescence. Overall, 45.6% females reported...
Warfarin is a widely used oral anticoagulant. Determining the correct dose required to maintain international normalised ratio (INR) within therapeutic range can be challenging. In previous trial, we showed that dosing algorithm incorporating point-of-care genotyping information ('POCT-GGD' approach) led improved anticoagulation control. To determine whether this approach could translate into clinical practice, undertook an implementation project using matched cohort design.At three clinics...
Abstract Objective To explore experiences, benefits and concerns associated with remote (telephone/video) consultations from the perspectives of children young people juvenile idiopathic arthritis (JIA), their parents health professionals who were members a multidisciplinary team in paediatric rheumatology setting. Methods Qualitative design (Interpretive Description) utilizing observation follow-up interviews (7–18 years) JIA, professionals. The setting was tertiary clinic hospital...
Abstract Background Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening reactions that cause blistering of the skin mucous membranes. Survivors can experience long term physical psychological complications. The ‘My SJS Passport’ was co-produced by Patient Public Involvement group research team at Wolfson Centre for Personalised Medicine to improve care experiences survivors. Objectives aim study implement in a real-world setting evaluation those with...
Background: Previous studies exploring risk-taking behaviour on holiday are typically limited to single nationalities, confounding comparisons among countries. Here we examine the sexual of holidaymakers three nationalities visiting Ibiza and Majorca. Methods: A comparative cross-sectional study design was used focusing British, Spanish German in age range 16–35 years. Overall, 3003 questionnaires were gathered at airports Majorca from returning home. Results: Of those surveyed, 71.1%...
Transition from child to adult status is a crucial stage in young people's lives. It important that people continue receive appropriate endocrine care throughout and following transfer paediatric services. This study examined indicators of patient loss follow-up at initial identify implications for transitional practice research.A retrospective analysis data services person's transition clinic was conducted. Attendance 103 patients transferred the Young Person's Clinic were analysed...
The aim of this study was to identify the most important determinants accident and emergency (A&E) attendance in disadvantaged areas. A total 3510 residents from 20 neighbourhoods North West Coast area England completed a comprehensive public health survey. Participants were asked complete general background information, as well information about their physical health, mental lifestyle, social issues, housing environment, work finances, healthcare service usage. Only one resident per...
Patient choice and access to health care is compromised by many barriers including travel distance. Individuals with the human immunodeficiency virus (HIV) can seek free specialist in Britain, without a referral, providing flexible services. Willingness beyond local services for preferred has funding service implications. Data from an enhanced HIV surveillance system were used explore geodemographic clinical factors associated accessing treatment We extracted data on location, type frequency...
S ummary . Previous research has indicated that children enter the task of learning to read in a state cognitive confusion regarding function and nature task. The present investigation was addressed hypothesis cultural differences home background are an important influence development children's understanding purpose writing their concepts language units employed written code. 92 non‐Indian Canadian at kindergarten were compared with 72 pupils from two Indian bands which there is no...
Adolescent health is a growing concern. High rates of binge drinking and teenage pregnancies, documented in the UK, are two measures defining poor wellbeing. Improving wellbeing through schools priority but information on impact alcohol use, sexual activity among schoolchildren limited. A cross-sectional survey using self-completed questionnaires was conducted 3,641 aged 11-14 years due to participate sex relationships education pilot programme 15 high North West England. Bivariate...
<h3>Objectives:</h3> To explore sexual behaviour and risk-taking among British backpackers in Australia to investigate the influence of substance use social settings on abroad. <h3>Methods:</h3> A cross-sectional design was used. The questionnaire gathered information 12 months prior leaving UK during backpackers' stays Australia. total 1008 backpackers, recruited hostels Sydney Cairns, were included study. <h3>Results:</h3> In total, 73.2% had sex their stay Australia, including 68.9% those...
Objective There is concern about long-term safety of direct oral coagulants (DOACs) in clinical practice. Our aim was to investigate whether the introduction DOACs compared with vitamin-K antagonists England associated a change admissions for bleeding or thromboembolic complications. Setting 5508 General practitioner (GP) practices between 2011 and 2016. Participants All GP registered population size greater than 1000 that had data all 6 years. Main outcome measure The rate emergency...
The Chief Medical Officer for England has developed the first guidance in and some of internationally on alcohol consumption by children. Using most recent iteration a large biennial survey schoolchildren we measure extent to which young people's drinking fell within guidelines just prior their introduction characteristics individuals whose does not; how related harms relate compliance; risk factors associated with behaving outside guidance. A cross-sectional was conducted utilising...
Patients with antiphospholipid antibody syndrome (APA) are at elevated risk of venous and arterial thromboembolic complications. Oral anticoagulation warfarin is recommended for secondary prevention thromboembolism, but warfarin-related outcomes have not been systematically investigated when therapy managed by a dedicated clinic. The objectives the study were to evaluate monitoring outcomes, clinical endpoints use healthcare resources as result complications in patients APA compared group...
Abstract Background The Household Health Survey (HHS) was developed to understand the socioeconomic determinants of mental and physical health, health inequalities in social care. This paper aims provide a detailed rationale development implementation survey explore socio-economic variations Methods comprehensive longitudinal public designed piloted disadvantaged area England, comprising questions on housing, lifestyle, issues, environment, work, finances. After piloting, HHS implemented...
Background There is uncertainty around the costs and health impacts of undiagnosed mental problems. Aims Using survey data, we aim to understand health-related quality-of-life decrements from anxiety/depression. Method We analysed data two waves North West Coast Household Health Survey, which included questions on disease, medications, Patient Questionnaire 9 (PHQ-9) Generalised Anxiety Disorder 7 (GAD-7) scores (depression anxiety scales). People were judged as having anxiety/depression...
Background After the rapid implementation of digital health services during COVID-19 pandemic, a paucity research exists about suitability remote consulting in people with intellectual disabilities and their carers, particularly for neuropsychiatric reviews. Aim This study examines when routine is suitable this population. Method A survey was conducted examining preference between face-to-face video consultations ongoing reviews within rural countywide disability service Cornwall, England...