A5111006263- Systemic Lupus Erythematosus Research
- Adolescent and Pediatric Healthcare
- Immune Cell Function and Interaction
- Autoimmune and Inflammatory Disorders Research
- Pharmaceutical studies and practices
- Pharmaceutical Economics and Policy
- Atherosclerosis and Cardiovascular Diseases
- Mobile Health and mHealth Applications
- Primary Care and Health Outcomes
- Diabetes and associated disorders
- Telemedicine and Telehealth Implementation
- Family and Patient Care in Intensive Care Units
- Childhood Cancer Survivors' Quality of Life
- Vestibular and auditory disorders
- Children's Rights and Participation
- Mental Health and Patient Involvement
- Social Media in Health Education
- Cell Adhesion Molecules Research
- Pharmacovigilance and Adverse Drug Reactions
- T-cell and B-cell Immunology
- Healthcare Systems and Technology
- Health Policy Implementation Science
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Inflammatory Bowel Disease
University of Liverpool
2020-2025
Alder Hey Children's NHS Foundation Trust
2019-2024
Alder Hey Children's Hospital
2020
Children's Hospital at Westmead
2017
Birmingham Children's Hospital
2009
Abstract Objective To explore experiences, benefits and concerns associated with remote (telephone/video) consultations from the perspectives of children young people juvenile idiopathic arthritis (JIA), their parents health professionals who were members a multidisciplinary team in paediatric rheumatology setting. Methods Qualitative design (Interpretive Description) utilizing observation follow-up interviews (7–18 years) JIA, professionals. The setting was tertiary clinic hospital...
A treat-to-target (T2T) approach, where treatment is escalated until a specific target achieved, and re-escalated if the lost, has been proposed as strategy to improve Childhood Systemic Lupus Erythematosus (cSLE) outcomes. Previous studies involving children young people (CYP) have identified that concept of T2T can be difficult understand by CYP their families. We aimed explore views participating in existing public patient involvement (PPI) groups relation animation being developed...
To derive childhood-onset SLE (cSLE) specific remission definitions for future treat-to-target (T2T) trials, observational studies, and clinical practice.
Childhood-onset systemic lupus erythematosus (cSLE), representing 15%-20% of individuals with SLE, has been difficult to study globally due differences between registries. This initiative, supported by Childhood Arthritis Rheumatology Research Alliance (CARRA) and Paediatric European Society (PReS), aims create Core Expanded cSLE Datasets standardise enhance research worldwide. 21 international experts 4 patients participated in a Delphi process (questionnaires, 2 topic-specific focus groups...
Abstract Background/Aims International interest in development of treat-to-target (T2T) both childhood-onset systemic lupus erythematosus (cSLE) and adult-onset SLE (aSLE) is increasing. T2T could facilitate more effective structured use treatments, aggressively controlling disease activity, preventing organ damage, improving health-related quality life. The first step the selection an appropriate target. Remission deemed ultimate target, but may not be attainable by all. Low activity (LDA),...
KN, a 12-year-old girl, presented with one day history of central abdominal pain, vomiting against nine year significant constipation requiring previous surgical washouts. KN born at term after uncomplicated pregnancy and unremarkable perinatal period. She passed meconium on life. Developed ‘functional’ age three ultimately insertion chait caecostomy button nine. Re-presented intestinal pseudo-obstruction 12. Full blood count, electrolytes, CRP, ESR, immunoglobulins, C3, C4, coeliac...
Background UK patients of all ages can contribute to the Medicines and Healthcare Regulatory Agency (MHRA) Yellow Card scheme (YCS), reporting suspected adverse drug reactions (ADRs). Children’s young people’s (CYPs) contribution to, awareness of, YCS is not known. Methods Suspected ADR reports received by MHRA from 01/01/2008 29/11/2018 were examined. Prospective data CYP parents in paediatric outpatients collected as part QUestionnaire study about Adverse Drug ReAcTions In Children...