- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Colorectal Cancer Surgical Treatments
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Genetic factors in colorectal cancer
- COVID-19 and healthcare impacts
- Neuroendocrine Tumor Research Advances
- Colorectal and Anal Carcinomas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Screening and Detection
- Cancer, Hypoxia, and Metabolism
- Nutrition and Health in Aging
- Diabetes Management and Research
- Helicobacter pylori-related gastroenterology studies
- Abdominal vascular conditions and treatments
- Gallbladder and Bile Duct Disorders
- Esophageal Cancer Research and Treatment
- Cancer Diagnosis and Treatment
- Pancreatic function and diabetes
Kochi Medical School Hospital
2016-2025
Kōchi University
2016-2025
University of Kochi
2023
Obayashi (Japan)
2015
Johns Hopkins Medicine
2009-2014
Johns Hopkins University
2009-2014
Makino Botanical Garden
2011
Kyushu University
2010
Federico II University Hospital
2009
University of Bologna
2009
Abstract This study assessed the impact of postoperative complications on colorectal cancer survival and recurrence after curative surgery using pooled individual patients’ data from three large phase III randomized trials. In total, 5530 patients were included in this study. The classified as those with (C group) without ( NC group). risk factors for overall OS ) disease‐free DFS analyzed. Postoperative found 861 (15.6%) patients. rates at 5 years 68.9% 74.8%, respectively, C group 75.8%...
Abstract Aim This study aimed to investigate the effect of coronavirus disease pandemic on number surgeries for gastroenterological cancer cases in Japan. Methods The data recorded National Clinical Database Japan between 2018 and 2020 were utilized this study. Five specific primary cancers surgery acute diffuse peritonitis considered endpoints. We divided period into prepandemic postpandemic (after April 2020) periods examined relation clinical factors. Results Overall, 228 860 analyzed....
OBJECTIVE Intensive insulin therapy (IIT) reduces morbidity and mortality in patients surgical intensive care units. The aim of this study is to assess the effect IIT using a closed-loop system hepatectomized patients. RESEARCH DESIGN AND METHODS Patients were randomly assigned receive system: an artificial pancreas (AP group) or conventional sliding-scale method (SS group). RESULTS incidence surgical-site infection AP group was significantly lower than that SS group. length hospitalization...
Stem cell therapy has shown promise in treating a variety of pathologies including skin wounds, but practical applications remain elusive. Here, we demonstrate that endogenous stem mobilization produced by AMD3100 and low-dose tacrolimus is able to reduce 25% the time complete healing full-thickness wounds created surgical excision. Equally important, was accompanied reduced scar formation regeneration hair follicles. Searching for mechanisms, found combined with mobilized increased number...
The coronavirus disease 2019 (COVID-19) pandemic had resulted in either failure to provide required medical resources or delayed treatment for gastric cancer patients. This study aimed investigate the impact of COVID-19 on incidence postoperative complications using a nationwide Japanese database patients undergoing distal gastrectomy cancer.
Most patients with hepatocellular carcinoma (HCC) have underlying liver cirrhosis that is frequently associated a state of protein energy malnutrition. The aim this study was to evaluate the clinical benefit perioperative supplementation branched-chain amino acid-enriched nutrient-mixture for undergoing resection HCC.A total 112 HCC who underwent hepatic were enrolled in study. These divided into two groups: 40 received (AEN group) and 72 did not (control group). Laboratory data,...
In Brief BACKGROUND: Protocols for tight control of blood glucose can be difficult to achieve in the surgical setting, especially when relying upon intermittent testing. A continuous monitoring system facilitate management. present study, we compared measured continuously (STG-22™, Nikkiso, Tokyo, Japan), during surgery with coincident measurements obtained intermittently using a conventional laboratory glucometer (ABL™ 800FLEX (Radiometer Medical Aps, Brnshj, Denmark). The goal study was...
BACKGROUND: Most previous reports to analyze risk factors for peritoneal recurrence in patients with colon cancer have been observational studies of a population-based cohort. OBJECTIVE: This study aimed determine the stage II III who underwent curative resection. DESIGN: was pooled analysis using combined database obtained from 3 large phase randomized trials (N = 3714). SETTINGS: Individual patient data were collected Japanese Foundation Multidisciplinary Treatment Cancer clinical 7, 15,...
<h3>Importance</h3> Women are vastly underrepresented in surgical leadership and management Japan. The lack of equal opportunities for training is speculated to be the main reason this disparity; however, hypothesis has not been investigated thus far. <h3>Objective</h3> To examine gender disparity number experiences among Japanese surgeons. <h3>Design, Setting, Participants</h3> This retrospective, multicenter cross-sectional study used data from National Clinical Database, which contains...
The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted the allocation of medical resources, including cancer screening, diagnosis, and treatment. We aimed to investigate effects on morbidity mortality following hepatectomy for hepatocellular carcinoma (HCC).
This study aimed to investigate the effects of coronavirus disease 2019 pandemic on morbidity and mortality after advanced hepatectomy by surgical volume in Japan. Data from patients who underwent between 2018 2022 Japanese National Clinical Database were collected. The transition number hepatectomies changes risk-adjusted major complication rates based type institutions certified Japan Society Hepato-Biliary-Pancreatic Surgery investigated. A total 33 454 cases included. gradually...
ABSTRACT Aim This study evaluated the short‐term outcomes of low anterior resection for rectal cancer in Japan before and after COVID‐19 pandemic, with a particular focus on timing its reclassification within May 2023. Methods Using data from Japanese National Clinical Database, we analyzed 109 754 cases between January 2018 December 2023, categorized into pre‐pandemic (February 2020 earlier), pandemic (March 2020–April 2023), post‐pandemic (May 2023 onward) periods. Trends number cases,...
Abstract Background Trastuzumab deruxtecan (T-DXd) has been approved for the treatment of human epidermal growth factor receptor-2 (HER2)-positive gastric cancer and other indications in several countries is considered moderately or highly emetogenic. The management nausea vomiting associated with T-DXd not fully evaluated effectiveness conventional prophylaxis remains unknown. Methods This open-label, randomized, multicenter, phase 2 study aimed to investigate optimal antiemetic therapy...