A5101798043- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- HER2/EGFR in Cancer Research
- Pancreatic and Hepatic Oncology Research
- Cancer Research and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- Carbohydrate Chemistry and Synthesis
- Breast Cancer Treatment Studies
- Asymmetric Synthesis and Catalysis
- Cancer therapeutics and mechanisms
- Cancer Cells and Metastasis
- Galectins and Cancer Biology
- Chemotherapy-related skin toxicity
- Chronic Lymphocytic Leukemia Research
- Peptidase Inhibition and Analysis
Hakodate Central General Hospital
2023-2025
Tokai Central Hospital
2013-2024
Tochigi Cancer Center
2020-2023
Suita Tokushukai Hospital
2023
Japanese Foundation for Multidisciplinary Treatment of Cancer
2012-2022
Takeda (Japan)
2016-2018
Asahikawa Medical University
2012-2018
Yokohama City University
2012-2018
National Hospital Organization
2018
Osaka City University
2018
Abstract This study assessed the impact of postoperative complications on colorectal cancer survival and recurrence after curative surgery using pooled individual patients’ data from three large phase III randomized trials. In total, 5530 patients were included in this study. The classified as those with (C group) without ( NC group). risk factors for overall OS ) disease‐free DFS analyzed. Postoperative found 861 (15.6%) patients. rates at 5 years 68.9% 74.8%, respectively, C group 75.8%...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnalysis of the specificity five murine anti-blood group A monoclonal antibodies, including one that identifies type 3 and 4 determinantsKoichi Furukawa, Henrik Clausen, Senitiroh Hakomori, Junichi Sakamoto, Katherine Look, Arne Lundblad, M. Jules Mattes, Kenneth O. LloydCite this: Biochemistry 1985, 24, 26, 7820–7826Publication Date (Print):December 17, 1985Publication History Published online1 May 2002Published inissue 17 December...
Objectives. To characterize body composition phenotypes using a dual-energy X-ray absorptiometry (DXA) method and to explore factors potentially contributing alterations in Vietnamese women with early RA. Methods. A total of 105 RA (disease duration ≤3 years) age-matched healthy underwent physical examination, regional lean mass (LM) fat (FM) DXA. The 28-joint DAS (DAS-28) disability HAQ score, nutrition, activity medications were recorded. Results. Means weight BMI similar patients...
The phase III ACHIEVE trial conducted in Japan was one of six prospective studies included the International Duration Evaluation Adjuvant Therapy collaboration, which explored whether 3 months adjuvant fluorouracil, leucovorin, and oxaliplatin (FOLFOX) or capecitabine (CAPOX) therapy would be noninferior to 6 treatment patients with curatively resected stage colon cancer. We report final analyses survival long-term safety.Eligible were randomly assigned (1:1) either chemotherapy (modified...
Differences in oncological outcomes between conservative and surgical treatments for anastomotic leakage (AL) patients undergoing colorectal cancer surgery remain unclear. From July 2011 to June 2020, 385 underwent curative resection with double-stapling anastomosis left-sided colon rectal cancers. Among them, 33 who experienced AL were retrospectively evaluated categorized into two groups: (n = 20) 13). In the group, abdominal lavage using a sufficient amount of normal saline was performed...
Monoclonal antibody mAbA33 recognizes a unique cell surface protein of colorectal cancer, the A33 antigen. Phase I/II studies have shown highly selective targeting radio-labeled in patients with metastatic opening up possibility A33-directed therapy. To better understand basis patients, present study was designed to define distribution normal organs and examine expression broad range tumor types. Immunohistochemical analysis tissues identified large small intestinal mucosa as principal sites...
A panel of 7 mouse monoclonal antibodies and the lectin from Ulex europeus, detecting blood-group-related antigens ABH Lewis systems, have been used to define distribution these antigenic structures within human gastrointestinal tract, characterize their expression modulation in colorectal carcinomas. The reagents employed detect following blood-group specificities: (all variants), B, H (type 2), Lewisa, Lewisb, X (Lewisx), Y (Lewisy) type 1 precursor chain. Immunohistochemical studies...
ObjectivesThis is the first phase II study to evaluate efficacy and tolerability of first-line FOLFIRI, as well influence uridine diphosphate glucuronosyl transferase 1, family polypeptide A1 gene (UGT1A1) *28/*6 polymorphism, in Japanese metastatic colorectal cancer patients.
Preoperative serum levels of carcinoembryonic antigen (CEA) and/or carbohydrate 19.9 (CA19.9) were measured in 90 patients with advanced pancreatic cancer. CEA was above the cutoff 5.0 ng/ml 51% and CA19.9 limit 37 U/ml 87% patients. High preoperative related to a poor prognosis In multivariate analysis, hazard rate significantly higher high-CEA group (>2.5 ng/ml) compared low-CEA (<2.4 mg/ml). An increase within 1 month after operation also rate. This study reconfirms prognostic importance...
Our objective was to evaluate the efficacy and safety of capecitabine in chemotherapy-naive patients with unresectable advanced or metastatic gastric cancer. An open-label multicenter phase II study conducted for previously untreated Oral 828 mg/m2 twice daily given on days 1-21 every 4 weeks. Baseline characteristics 60 enrolled were: male/female 49/11, median age 64 years (range 28-74), good performance status (ECOG 0-1) 98% 27 had prior gastrectomy (45%). A treatment cycles were...