A5000354358- Complement system in diseases
- Blood Coagulation and Thrombosis Mechanisms
- Iron Metabolism and Disorders
- Renal Diseases and Glomerulopathies
- Hemoglobinopathies and Related Disorders
- Pregnancy and preeclampsia studies
- Venous Thromboembolism Diagnosis and Management
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Atrial Fibrillation Management and Outcomes
- Platelet Disorders and Treatments
- Cardiac Arrhythmias and Treatments
- Potassium and Related Disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Skin Protection and Aging
- Ferroptosis and cancer prognosis
- Maternal and fetal healthcare
- Heparin-Induced Thrombocytopenia and Thrombosis
- Antiplatelet Therapy and Cardiovascular Diseases
- Sleep and related disorders
- Viral Infectious Diseases and Gene Expression in Insects
- Pneumonia and Respiratory Infections
- Diagnosis and Treatment of Venous Diseases
- Sleep and Work-Related Fatigue
- Clinical Laboratory Practices and Quality Control
Palmerston North Hospital
2025
Ben-Gurion University of the Negev
2012-2024
Soroka Medical Center
2012-2023
University Medical Center
2020-2021
Emek Medical Center
2021
Barzilai Medical Center
2012
Acute interstitial pneumonia is a rapidly progressive disease frequently leading to respiratory failure and mechanical ventilation. The prognosis usually poor despite aggressive diagnostic treatment efforts.In this retrospective cohort survey, we enrolled patients with hypoxemic who met predefined criteria of acute idiopathic pneumonia. Patients' records, radiologic studies, pathologic specimens were reviewed. All data recorded in each patient's study file subsequently analyzed.Our consisted...
Selective pharmacological activation of the adenosine 1 receptor (A<sub>1</sub>R) is a promising new approach to achieve potent block atrioventricular (A-V)–nodal conduction without significant cardiovascular side effects. The purpose present study was evaluate profile INO-8875, highly selective A<sub>1</sub>R agonist, and compare its properties with <i>N</i>-[3(<i>R</i>)-tetrahydrofuranyl]-6-aminopurine riboside (CVT-510), which has already been shown induce negative dromotropic effects...
Collagen is the major structural protein in extracellular matrix of skin produced by fibroblasts. UV exposure results infiltration neutrophils within epidermis and dermis, inducing collagen damage contributing to process photo-aging. Collagen-3 an integral component with collagen-1, important regulator collagen-1 fibrillogenesis. Addition activated TNFα normal human dermal fibroblast cultures, but not their supernatant, caused significant collagen-3 damage. To study whether Lumenato can...
Aims The aim of the study was to analyze interaction between celecoxib and low dose aspirin for COX‐1 binding its consequences on aspirin‐mediated antiplatelet effects. Methods We investigated ex vivo measured resulting applied mechanism‐based pharmacokinetic−pharmacodynamic (PKPD) modelling these data predict in platelet aggregation different doses administration schedules celecoxib. Results predictions PK‐PD model were consistent with results from previous studies that indicate can...
1 IntroductionSevere COVID‐19 is associated with an important increase of von Willebrand factor and mild lowering ADAMTS13 activity that may, in the presence a strong inflammatory reaction, risk acute thrombotic thrombocytopenic purpura (TTP). Although episodes immune‐mediated TTP or SARS‐CoV‐2 vaccination have been reported, data about clinical evolution hereditary (hTTP) during pandemic are scarce.2 MethodWe conducted survey among adult patients International Hereditary Registry...
One of the most clinically important effects following administration packed cell transfusion (PCT) is hyperkalemia, which can cause severe life-threatening cardiac arrhythmias. This retrospective population-based cohort study included adults hospitalized between January 2007 and December 2019 in a general intensive care unit for 24 h or more, with normal levels serum potassium on admission. We assessed changes after one cells sought to identify clinical parameters that may affect these...
: The COVID-19 pandemic markedly increased the number of patients with infection-related acute respiratory distress syndrome who required extracorporeal membrane oxygenation (ECMO) and multiple blood transfusions. This study aimed to assess a potential correlation between daily rate transfused products intensive care unit (ICU) outcome ECMO-supported patients.
Abstract Background Packed red blood cell (RBC) transfusion is a very common and frequently lifesaving therapeutic intervention, but liberal policy may be associated with inferior patient outcomes. Various guidelines have been proposed to reduce the rate of unnecessary RBC transfusions. However, physicians' proficiency in such effect training on administration remain unknown. Methods We performed questionnaire‐based assessment knowledge tertiary hospital Israel, followed by an analysis six...
The decision-making process of introducing new technologies into the health care system must minimize individual interests policy makers and reduce possible biases faults while building up best portfolio available. main obstacles for achieving these goals may relate to large number assessed each year budget available annually is limited.