A5042822303- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Eosinophilic Esophagitis
- Dysphagia Assessment and Management
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Head and Neck Cancer Studies
- Colorectal Cancer Screening and Detection
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal and Anal Carcinomas
- Gallbladder and Bile Duct Disorders
- Clinical Nutrition and Gastroenterology
- Foreign Body Medical Cases
- Intestinal and Peritoneal Adhesions
- Biliary and Gastrointestinal Fistulas
- Diet and metabolism studies
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Surgical Treatments
Osaka University of Pharmaceutical Sciences
2021-2025
Tohoku Medical and Pharmaceutical University Hospital
2023
Osaka Medical and Pharmaceutical University
2018-2021
Teine Keijinkai Hospital
2021
National Institute of Diabetes and Digestive and Kidney Diseases
2019-2020
ProQuest (United States)
2019-2020
Osaka International Cancer Institute
2017-2020
The Japanese Society of Gastroenterological Surgery
2020
Showa University
2020
Jikei University School of Medicine
2020
Abstract Background and study aim Underwater endoscopic mucosal resection (UEMR) was recently developed in a Western country. A prospective cohort to investigate the effectiveness of UEMR conducted patients with small superficial nonampullary duodenal adenomas. Patients methods adenomas ≤ 20 mm were enrolled. After lumen had been filled physiological saline, performed without submucosal injection. Endoclip closure attempted for all defects after UEMR. Follow-up endoscopy biopsy 3 months...
The incidence of post-endoscopic submucosal dissection (ESD) coagulation syndrome (PECS) can be decreased by closing mucosal defects. However, large defects after colorectal ESD cannot closed endoscopically. We established line-assisted complete clip closure (LACC), a novel technique for ESD. evaluated the prophylactic efficacy LACC preventing PECS.Sixty-one consecutive patients on whom was attempted from January 2016 to August were analyzed. After exclusion with incomplete and adverse...
Abstract Background Cold snare polypectomy (CSP) to remove multiple duodenal adenomas (MDAs) in patients with familial adenomatous polyposis (FAP) could be an effective and less invasive method than more extensive surgery. The aim of the present study was determine safety this procedure. Methods This prospective exploratory included 10 consecutive FAP MDAs who underwent CSP for as many 50 adenomas. primary outcome incidence severe adverse events. Results were enrolled 332 CSPs from June 2016...
The true incidence of incomplete muscularis mucosa resection with cold snare polypectomy (CSP) is unknown. We examined the both and without defect protrusion (CSDP).We prospectively enrolled patients undergoing for 4 to 9mm nonpedunculated polyps. evaluated presence CSDP immediately following CSP biopsied or center mucosal CSDP. any residual polyp in biopsies was histologically. primary outcome layer defined as biopsies.From August 2017 October 2018, 188 were screened, 357 polyps included....
Abstract Background Although proton pump inhibitors (PPIs) or potassium-competitive acid blocker (PCAB) are useful in peptic ulcer prevention, their efficacy preventing other gastrointestinal bleeding remains unclear. This study aimed to identify the status of modern era when PPIs widely used. Methods included patients who underwent percutaneous coronary intervention (PCI) between 2018 and 2019 at two high-volume centers. Patients were categorized based on whether they experienced within 2...
Abstract Endoscopic injection sclerotherapy (EIS) is a useful prophylactic hemostatic procedure for esophageal varices. However, injecting sclerosing agents into blood vessels technically challenging and often ineffective. Gel‐immersion EIS (GI‐EIS) may facilitate easier intravascular agent by dilating the varices enhancing scope stability maintaining low intra‐gastrointestinal pressure. Therefore, we aimed to evaluate effectiveness safety of this procedure. This retrospective study included...
OBJECTIVES: The reported 1- and 3-year overall survival rates after esophagectomy for stage I superficial esophageal squamous cell carcinoma (SESCC) are 95–97% 86%, those definitive chemoradiotherapy (CRT) 98% 89%, respectively. This study was performed to elucidate the efficacy safety of another treatment option SESCC: endoscopic resection (ER) followed by CRT. METHODS: We retrospectively reviewed survival, recurrence, grade ≥3 adverse events consecutive patients who refused underwent ER...
Endoscopic biopsies for nonampullary duodenal epithelial neoplasms (NADENs) can induce submucosal fibrosis, making endoscopic resection difficult. However, no biopsy-free method exists to distinguish between NADENs and non-neoplasms. We developed a diagnostic algorithm based on magnifying endoscopy findings evaluated the model's ability.Magnified images lesion histology were collected consecutively January 2015 April 2016. Diagnosticians classified surface patterns as pit, groove or absent....
Background and Aim Underwater endoscopic mucosal resection (UEMR) is effective for superficial non‐ampullary duodenal epithelial neoplasms (SNADEN). However, the incidence of residual lesion after UEMR, especially large lesions (≥20 mm), their prognosis remain unclear. We aimed to assess further outcomes UEMR SNADEN. Methods carried out a retrospective study at tertiary cancer institute. Candidates were systematically retrieved from an pathological database January 2013 April 2018. Results A...
Metachronous cancer in patients with head and neck (HNC) is common associated a poor prognosis. We aimed to evaluate the incidence of metachronous at different sites according age diagnosis index HNC. collected data on 2011 oral cancer, oropharynx hypopharyngeal laryngeal as cancers using Osaka International Cancer Institute Registry database between 2005 2016. Among these, we analyzed 1953 after excluding 5 who were not followed-up 53 simultaneous multiple cancers. evaluated cumulative...
Although the use of endoscopic submucosal dissection (ESD) as a minimally invasive treatment for large superficial colorectal neoplasms is increasing, ESD remains technically challenging. As perforation in colorectum generally considered to be associated with higher risk complications, aim this study was investigate characteristics caused by ESD.This retrospective included 635 lesions treated ESD, between February 2011 and December 2015, tertiary cancer center. We evaluated compared clinical...
Stratifying gastric cancer (GC) risk and endoscopy findings in high-risk individuals may provide effective surveillance for GC. We developed a computerized image- analysis system endoscopic images to stratify the of GC.The was trained using taken during examinations with non-magnified white-light imaging. Patients were classified as (patients GC), moderate-risk current or past Helicobacter pylori infection atrophy), low-risk no history H. atrophy). After selection, 20,960, 17,404, 68,920...
Abstract Background and Aim Endoscopic resection for early gastric cancer (EGC) is widely performed. However, there still a paucity of strong evidence regarding long‐term outcomes after endoscopic submucosal dissection (ESD) the expanded indication criteria Japanese guidelines (ver. 2010). Methods was performed in patients with EGC that met criteria: (i) cT1a, differentiated‐type 2 to 5 cm, ulcer negative or (ii) ≤3 positive. Patients whose pathological examination fulfilled curative were...
Abstract Background and study aims Complete closure of large mucosal defects after colorectal endoscopic submucosal dissection (C-ESD) is considered impossible in most cases because the limited width open clip. We therefore invented a simple technique using clip-and-line, named “line-assisted complete (LACC)”, assessed its technical feasibility. Patients methods Between January February 2016, we performed LACC 11 patients C-ESD included them this retrospective feasibility study. Outcome...
To investigate the efficacy of recombinant human soluble thrombomodulin (rTM) in preventing development walled-off necrosis (WON) severe acute pancreatitis (SAP) patients. We retrospectively analyzed 54 SAP patients divided into two groups: treated by rTM (rTM group, 24 patients) and not (control 30 patients). was administered to with disseminated intravascular coagulation (DIC). Initially, on admission day, we recorded patient severity pancreatic necrosis/ischemia positive or negative. Then...
Multiple Lugol-voiding lesions (LVLs) on Lugol chromoendoscopy can predict the development of metachronous multiple cancers in esophagus and head neck regions. However, sometimes causes adverse events such as chest pain discomfort. We therefore investigated endoscopic findings narrow band imaging (NBI) or blue laser (BLI) that correspond to presence LVLs patients with esophageal squamous cell carcinoma.First, we NBI/BLI corresponding individual small (one-to-one correspondence). Second,...
A 70-year-old man who had undergone treatment for gastroesophageal reflux disease (GERD) by a family doctor presented to our hospital with severe heartburn and dysphagia despite taking vonoprazan (20 mg) 3 months. diagnosis of vonoprazan-refractory nonerosive was made based on esophagogastroduodenoscopy esophageal function examinations. The patient elected undergo endoscopic GERD. Therefore, we performed using the submucosal dissection (ESD-G) technique developed at institution. After...
Endoscopic resection of a neoplasm involving colonic diverticulum is challenging. We successfully treated 3 patients with neoplasms traction-assisted colorectal endoscopic submucosal dissection (ESD) using clip and line (TAC-ESD). The procedure was performed pediatric videocolonoscope (PCF-Q260JI, Olympus, Tokyo, Japan) cap (D-201-11804, Olympus) an endoknife (Flushknife BT 1.5 mm, DK2618JB-15, Fujifilm, Japan). Before the procedure, patient's position changed to move fluid opposite side...
<b><i>Background/Aims:</i></b> Currently, there is no study evaluating the effect of acotiamide on transient lower esophageal sphincter relaxations (TLESRs). The aim this was to evaluate TLESRs using simultaneous high-resolution manometry (HRM) and impedance-pH monitoring. <b><i>Methods:</i></b> Ten healthy subjects were enrolled. On day 1, underwent HRM recordings as a baseline. Subjects ate 750-kcal liquid meal; recording continued for 2 h...