A5087443447- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Head and Neck Cancer Studies
- Liver Disease Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Ophthalmology and Eye Disorders
- Thyroid Cancer Diagnosis and Treatment
- Ear and Head Tumors
- Oral and Maxillofacial Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Esophageal Cancer Research and Treatment
- Olfactory and Sensory Function Studies
- Glaucoma and retinal disorders
- Cerebral Venous Sinus Thrombosis
- Sinusitis and nasal conditions
- Glycosylation and Glycoproteins Research
- Lung Cancer Treatments and Mutations
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Esophageal and GI Pathology
- Salivary Gland Tumors Diagnosis and Treatment
- Allergic Rhinitis and Sensitization
- Foreign Body Medical Cases
- Head and Neck Anomalies
Shiga University of Medical Science
2019-2025
Nagoya University
2016-2024
Osaka International Cancer Institute
2018-2022
Kansai Rosai Hospital
1977-2021
Kōchi University
2021
Asahi General Hospital
1995-2020
RELX Group (Netherlands)
2020
Yodogawa Christian Hospital
2019
Osaka Medical Center for Cancer and Cardiovascular Diseases
2004-2018
University of Occupational and Environmental Health Japan
2018
The Japan Integrated Staging score (JIS score), which combines the Child–Turcotte–Pugh classification and tumor–node–metastasis staging, has been proposed as a better prognostic staging system for hepatocellular carcinoma (HCC) than Cancer of Liver Italian Program (CLIP) scoring system. In this study, validation was performed among larger patient population. A total 4,525 consecutive patients with HCC who had diagnosed at five institutions were included. Stratification ability, predictive...
Abstract 1 α ,25‐Dihydroxyvitamin D 3 (1,25(OH) 2 ) is known to be a hormonally active form of vitamin in the regulation intracellular and extracellular calcium levels differentiation myeloid cells epidermal keratinocytes. We found that ,24(R)‐dihydroxyvitamin (1,24(OH) ), novel synthetic derivative , also regulating 1,24(OH) had same affinity as 1,25(OH) for receptor isolated from epidermis newborn mice. The incubation mouse keratinocytes with induced their time‐ dose‐dependent manner,...
Extracting clinical terms from free-text format radiology reports is a first important step toward their secondary use. However, there no general consensus on the kind of to be extracted. In this paper, we propose an information model comprising three types entities: observations, findings, and modifiers. Furthermore, determine its applicability for in-house reports, extracted with state-of-the-art deep learning models compared results. We trained evaluated using 540 chest computed...
Postoperative peritoneal adhesion formation (PAF) is a distressing complication. Leptin, secreted by fat tissues, may be associated with PAF. However, the relationships between PAF and leptin are unclear. This study investigated impact of on after colorectal tumor resection. A cecum cauterization mouse model was used to investigate its association leptin. Mice score (AS) evaluated day 7 treatment. The clinical included patients who underwent elective resection temporary ileostomy April 2021...
<i>Objectives:</i> The conventional Japan Integrated Staging (c-JIS) score has been reported to effectively stratify patients with hepatocellular carcinoma (HCC). Recently, two new staging systems, the biomarker-combined JIS (bm-JIS) and BALAD score, have proposed. Both systems include three tumor markers: α-fetoprotein (AFP), lens culinaris agglutinin-reactive AFP des-γ-carboxy prothrombin specific for HCC. aim of this study is evaluate performance these systems....
The purpose of this study was to determine whether hepatic tissue oxygenation after ischemia-reperfusion procedures is an indicator for later liver injury. Partial ischemia in the induced by ligating left pedicles. Rats were divided into two groups according duration ischemia: group A (30-min ischemia) and B (60-min ischemia). Indices blood volume regional tissue, serum ALT levels histological appearance livers evaluated. Twenty-four hours reflow, all rats alive, whereas only 67% survived B....
Patients with esophageal cancer often display relapse at cervical nodes after surgery, but their prognosis and a suitable therapy remains unknown. We retrospectively reviewed the records for 35 patients who underwent esophagectomy lymphadenectomy then displayed lymph alone between 1985 2003 in order to observe prognostic factors such patients. Median survival time from date of recurrence all was 12 months 1-year, 2-year, 3-year 5-year rate 47.2%, 26.5%, 17.7% 8.8%, respectively. With regard...
Abstract Background and Aim: Although various staging systems for hepatocellular carcinoma (HCC) have been developed in recent years, there is no worldwide consensus which system best. The aim of the present study was to compare performance currently three systems: Japan integrated (JIS) score, new Barcelona Clinic Liver Cancer (BCLC) classification, Tokyo score. Methods: A total 290 consecutive patients with HCC before initial treatment at Kinki University between January 1999 December 2001...
AbstractElectrocochleography (ECoG) and glycerol test were performed in 51 Meniere ears. The positive rate of both tests was compared. ECoG 63% %, respectively. ears with result either 15 (29%) 43 (84%), higher a moderate to severe hearing loss at high frequencies, while the low frequencies. present study has demonstrated that is different selectivity detection endolymphatic hydrops from combination increases Meniere's disease.
Two new imaging modalities have been developed recently that are directed at the focal liver lesions: gadolinium ethoxybenzyl diethylene triamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance (MRI) and Sonazoid contrast-enhanced ultrasonography (CEUS). We investigated usefulness of these for diagnosis small (<2 cm), well-differentiated hepatocellular carcinoma (HCC). A total 15 nodules from 13 patients, which were histologically diagnosed as HCC, subjected to this study. Lesions...
<b><i>Objective:</i></b> Clinical staging is very important for optimal therapeutic strategy and prognostic prediction in patients with hepatocellular carcinoma (HCC). The Barcelona Clinic Liver Cancer (BCLC) system the most widely used best-validated method HCC. Similarly, conventional Japan Integrated Staging (c-JIS) score biomarker-combined JIS (bm-JIS) have also been reported to effectively stratify HCC patients. aim of this study was evaluate performance these...
The role of microcirculation in the pathogenesis alcoholic liver injury was investigated isolated perfused livers from fed rats. Infusion ethanol into portal vein at concentrations ranging 25 to 200 mmol/L increased pressure, which is an indicator hepatic vasoconstriction, a concentration-dependent fashion. Portal pressure started rise immediately on initiation load and remained higher than basal levels throughout period infusion. Release lactate dehydrogenase, cell injury, effluent...
Three hundred and thirteen cases of human thyroid tissues, comprising 39 nodular goiters from 34 females 5 males, 130 adenomas 93 37 144 carcinomas 99 45 males were used for the present immunohistochemical assessment estrogen receptor (ER) expression. Thirty-three follicular carcinoma, 115 papillary carcinoma 6 anaplastic included in malignant tumor group. Incidences ER-positive 23/39 (58.9%) goiter, 44/130 (33.8%) adenoma 26/144 (18.0%) cancer. In individual categories, 7/23 (30.4%)...
AbstractHow does a doctor make diagnosis based on his medical knowledge? A hypothesis is proposed concerning the diagnostic method of specialized doctors. The knowledge provided by an authority used to establish system for headache and facial pain named RHINOS. RHINOS above as represented programming language Prolog, which operative NEC PC-9801 microcomputer with reasonable CPU time. This implementation form benefited greatly from RHINOS's portability availability.RHINOS has four types...
The Japan Integrated Staging (JIS) score has been reported to have good stratification ability in patients with hepatocellular carcinoma (HCC). However, the JIS could not estimate malignant grade of HCC. aim this study was evaluate performance a new staging system: biomarker combined (bm-JIS) which includes three tumor markers: alpha-fetoprotein (AFP), Lens culinaris agglutinin-reactive AFP and des-gamma-carboxy prothrombin conventional score.A total 1,924 HCC were included study. We...