A5102854754- Parkinson's Disease Mechanisms and Treatments
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Neurological diseases and metabolism
- Cardiac Arrest and Resuscitation
- SARS-CoV-2 and COVID-19 Research
- MicroRNA in disease regulation
- COVID-19 and Mental Health
- Amyotrophic Lateral Sclerosis Research
- COVID-19 Pandemic Impacts
- Long-Term Effects of COVID-19
- Autism Spectrum Disorder Research
- Neurological disorders and treatments
- Circular RNAs in diseases
- Robotic Path Planning Algorithms
- Neuroinflammation and Neurodegeneration Mechanisms
- Autophagy in Disease and Therapy
- Video Analysis and Summarization
- Genetic Neurodegenerative Diseases
- Human Pose and Action Recognition
- Trauma and Emergency Care Studies
- Nuclear Receptors and Signaling
- Cancer-related molecular mechanisms research
- Nutritional Studies and Diet
- Video Surveillance and Tracking Methods
Tianjin University
2023-2025
Wuhan Institute of Technology
2025
Shandong University
2024
Nanjing University of Science and Technology
2024
Beijing Emergency Medical Center
2020-2023
Harbin Medical University
2023
Qingdao University
2023
Sichuan University
2015-2021
West China Hospital of Sichuan University
2015-2021
China State Shipbuilding (China)
2021
Background: Since the first case of a novel coronavirus (COVID-19) infection pneumonia was detected in Wuhan, China, series confirmed cases COVID-19 were found Beijing. We analyzed data 262 to determine clinical and epidemiological characteristics Methods: collected patients who transferred by Beijing Emergency Medical Sevice designated hospitals. The information on demographic, epidemiological, clinical, laboratory test for virus, diagnostic classification, cluster outcome obtained....
Abstract Chemotherapeutics can induce immunogenic cell death (ICD) by triggering autophagy and mediate antitumor immunotherapy. However, using chemotherapeutics alone only cause mild cell‐protective be incapable of inducing sufficient ICD efficacy. The participation inducer is competent to enhance autophagy, so the level promoted effect immunotherapy highly increased. Herein, tailor‐made cascade amplification polymeric nanoparticles STF@AHPPE are constructed tumor Arginine (Arg),...
Abstract Blood–brain barrier disruption and the neuroinflammatory response are significant pathological features that critically influence disease progression treatment outcomes. This review systematically analyzes current understanding of bidirectional relationship between blood– brain neuroinflammation in traumatic injury, along with emerging combination therapeutic strategies. Literature indicates blood–brain responses key following injury. In acute phase after characteristics include...
To investigate how larval feeding regimens influence development and deltamethrin resistance of Aedes albopictus to provide evidence for standardizing protocols in studies insecticide resistance. larvae a laboratory resistant strain were divided into 3 groups (n=500) reared with high, medium, low food availability (100, 50, or 25 mg daily the 1st 2nd instars, 500 250, 125 3rd 4th instars). The developmental time, pupation rate, adult emergence body weight, wing length recorded each group,...
Herein, we identified that HDAC11 is involved in the pathogenesis of AML and a potential therapeutic target for AML. Considering scarcity inhibitors, structurally novel inhibitors were developed, identifying A9 as most potent one, which phenocopied apoptosis induction, cell cycle arrest, differentiation promotion effects knockdown cells. Moreover, not only promoted iron uptake by upregulating TF TFRC but also release HMOX1, cooperatively led to homeostasis disruption consequent ferroptosis...
Radiation-induced intestinal injury (RIII) is one of the most common complications caused by radiotherapy for pelvic and abdominal tumors it seriously affects quality life patients. However, treatment acute RIII essentially symptomatic nutritional support an ideal means prevention lacking. Researchers have conducted studies at cellular animal levels found that some chemical or biological agents good therapeutic effects on may be used as potential candidates clinical treatment. This article...
Traumatic brain injury and Alzheimer’s disease share pathological similarities, including neuronal loss, amyloid-β deposition, tau hyperphosphorylation, blood–brain barrier dysfunction, neuroinflammation, cognitive deficits. Furthermore, traumatic can exacerbate disease-like pathologies, potentially leading to the development of disease. Nanocarriers offer a potential solution by facilitating delivery small interfering RNAs across for targeted silencing key genes implicated in Unlike...
Abstract Neurons display genomic fragility and show fragmented DNA in pathological degeneration. A failure to repair breaks may result cell death or apoptosis. Lithium protects retinal neurocytes following nutrient deprivation partial nerve crush, but the underlying mechanisms are not well defined. Here we demonstrate that pretreatment with lithium from ischemia-induced damage enhances light response rat retina ischemia–reperfusion injury. Moreover, found nonhomologous end-joining (NHEJ) is...
Introduction Guillain-Barré syndrome (GBS) is one of the most common causes acute flaccid paralysis, with up to 20%-30% patients requiring mechanical ventilation. The aim our study was develop and validate a ventilation risk nomogram in Chinese population GBS. Methods A total 312 GBS were recruited from January 1, 2015, June 31, 2018, whom 17% received least absolute shrinkage selection operator (LASSO) regression model used select clinicodemographic characteristics blood markers that then...