A5027676383- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Mast cells and histamine
- Respiratory and Cough-Related Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Autoimmune Bullous Skin Diseases
- Olfactory and Sensory Function Studies
- Eosinophilic Esophagitis
- Inflammatory mediators and NSAID effects
- Occupational exposure and asthma
- Dermatology and Skin Diseases
- Sinusitis and nasal conditions
- Nasal Surgery and Airway Studies
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Disorders and Syndromes
- Pharmaceutical studies and practices
- Insect and Pesticide Research
- Entomological Studies and Ecology
- Monoclonal and Polyclonal Antibodies Research
- Circadian rhythm and melatonin
- Phenothiazines and Benzothiazines Synthesis and Activities
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2016-2025
Universitat de Barcelona
2016-2025
Hospital Clínic de Barcelona
2015-2025
Instituto de Salud Carlos III
2015-2025
Odense University Hospital
2024
Escuela Nacional de Sanidad
2024
Nationwide Children's Hospital
2023
Spanish Clinical Research Network
2022
Imperial College London
2020-2021
Spanish Foundation for Science and Technology
2021
Discovered and described 40 years ago, non-specific lipid transfer proteins (nsLTP) are present in many plant species play an important role protecting plants from stressors such as heat or drought. In the last 20 years, sensitization to nsLTP consequent reactions foods has become increasing concern.The aim of this paper is review evidence for structure function allergens, cross-reactivity, sensitization, epidemiology allergy.A Task Force, supported by European Academy Allergy & Clinical...
Multiple plant-food sensitizations with a complex pattern of clinical manifestations are common feature lipid transfer protein (LTP)-allergic patients. Component-resolved diagnosis permits the allergen sensitization profile.We sought to clinically characterize and describe pollen molecular profile in patients LTP syndrome.Forty-five subjects were recruited, after being diagnosed multiple allergies sensitized LTP, but not any other allergen, according panel tested (Pru p 3 (LTP), Pru 1 (Bet v...
Summary Plant genetic engineering has the potential to introduce new allergenic proteins into foods but, at same time, it can be used remove established allergens. Here, we report molecular characterization of Lyc e 3, a tomato ( Lycopersicon esculentum ) allergen, and efficient down‐regulation its expression in transgenic plants. Following identification an immunoglobulin E (IgE)‐binding 9‐kDa polypeptide peel, designated partial amino acid sequence was determined by N‐terminal protein...
Abstract Objectives/Hypothesis: A degree of smell disturbance has been found in seasonal and perennial allergic rhinitis, but alterations olfaction patients with persistent rhinitis (PER) have not yet evaluated. The aims the study were to evaluate impact PER on sense smell, characterize this based self‐reported hyposmia (SRH) severity. Study Design/Methods: prospective controlled was performed 49 consecutive PER. subclassified depending severity presence SRH. Olfactory function evaluated by...
Cross-reactivity of plant foods is an important phenomenon in allergy, with geographical variations respect to the number and prevalence allergens involved this process, whose complexity requires detailed studies. We have addressed role thaumatin-like proteins (TLPs) cross-reactivity between fruit pollen allergies. A representative panel 16 purified TLPs was printed onto allergen microarray. The selected belonged sources most frequently associated peach allergy regions Spain. Sera from two...
To cite this article: Jáuregui I, Dávila Sastre J, Bartra del Cuvillo A, Ferrer M, Montoro Mullol Molina X, Valero A. Validation of ARIA (Allergic Rhinitis and its Impact on Asthma) classification in a pediatric population: The PEDRIAL study. Pediatr Allergy Immunol 2011; 22 : 388–392. Abstract Allergic rhinitis (AR) is the commonest chronic disease children. Asthma (ARIA) based symptom duration (intermittent vs. persistent) severity (mild moderate/severe) has not been yet validated Thus our...
To collect data on the efficacy and safety of omalizumab in 110 patients from 9 Spanish hospitals suffering chronic spontaneous urticaria (CSU) refractory to conventional treatment.A retrospective, descriptive analysis was performed, showing CSU who received as an off-label treatment October 2009 September 2012.Ninety (81.8%) exhibited a complete or significant response, 12 (10.9%) had partial 8 (7.2%) showed no response. Sixty-six (60%) were able stop all concomitant medications, remaining...
The study of cross-reactivity in allergy is key to both understanding. the allergic response many patients and providing them with a rational treatment In present study, protein microarrays co-sensitization graph approach were used conjunction an allergen microarray immunoassay. This enabled us include wide number proteins large patients, sensitization profiles among members LTP family. Fourteen LTPs from most frequent plant food-induced allergies geographical area studied printed into...
Summary Background Omalizumab (OmAb) has recently been approved for the treatment of diseases other than allergic asthma, including chronic urticaria. The exploration use OmAb in urticaria was based on presence IgE autoantibodies against autoantigens such as anti‐IgE, anti‐Fcε RI , and antibodies thyroid peroxidase certain patients with recognizes sequesters free to prevent its interaction Fcε . However, is equally rapidly effective autoimmune non‐autoimmune urticaria, suggesting possible...
Background: Although various relationships between the lower and upper airways have been found, association of bronchiectasis with chronic rhinosinusitis nasal polyps has not thoroughly evaluated. This study was undertaken to examine idiopathic postinfective polyposis. Methods: In a prospective study, 56 patients 32 were evaluated for polyposis by using EP 3 OS criteria assessing: symptoms score, endoscopy, sinonasal chest CT scan, lung function exhaled NO. Results: Most (77%) satisfied...
Food allergy is the most common cause of anaphylaxis. Changes in posture during acute reactions can trigger fatal outcomes, but impact allergic on cardiovascular system nonfatal remains poorly understood.