A5004651026- Antimicrobial Resistance in Staphylococcus
- Cancer-related molecular mechanisms research
- Pneumonia and Respiratory Infections
- Pleural and Pulmonary Diseases
- SARS-CoV-2 and COVID-19 Research
- Machine Learning in Bioinformatics
- MicroRNA in disease regulation
- Antifungal resistance and susceptibility
- Vitamin C and Antioxidants Research
- Listeria monocytogenes in Food Safety
- Cardiovascular Health and Disease Prevention
- IL-33, ST2, and ILC Pathways
- Quinazolinone synthesis and applications
- Essential Oils and Antimicrobial Activity
- COVID-19 Clinical Research Studies
- Engineering Structural Analysis Methods
- Salmonella and Campylobacter epidemiology
- Hemoglobin structure and function
- Asphalt Pavement Performance Evaluation
- Cancer Mechanisms and Therapy
- NF-κB Signaling Pathways
- Pediatric health and respiratory diseases
- Cystic Fibrosis Research Advances
- Asthma and respiratory diseases
- Pericarditis and Cardiac Tamponade
Jilin University
2019-2024
First Hospital of Jilin University
2019-2024
Ankang City Central Hospital
2022
Chang'an University
2020
Weatherford College
2019
Abstract Background Recent studies have shown 6'-O-galloylpaeoniflorin (GPF), a nature product extracted from the roots of paeoniflorin exerts anti-oxidant and anti-inflammatory activities. However, effects GPF on proliferation invasion in non-small cell lung cancer (NSCLC) cells not been clarified. Methods MTT assay was performed to determine cytotoxicity treatment NSCLC cells. Colony formation assay, scratch test transwell were vitro, respectively. An A549 xenograft mouse model confirm...
Abstract Asthma is a chronic respiratory disease with high heterogeneity in human. Different mouse models have been applied for investigation of pathogenesis and treatment asthma, which target on different cells, receptors pathways. Interleukin (IL-) 28B, member λ-interferons, shown to play protective role OVA-induced antigen-specific adaptive immune system dominant. However, the roles IL-28B protease-induced an independent are still unclear. Here, we used plant-derived cysteine protease,...
LncRNA PLAC2 has been characterized as a tumor suppressive lncRNA in glioma. We investigated the role of non-small cell lung cancer (NSCLC).A total 187 NSCLC patients were admitted by The First Hospital Jilin University from December 2010 to 2014. All diagnosed histopathological approaches. Transient transfections, RT-qPCR, invasion, and migration ability measurement, applied for experiments.PLAC2 was down-regulated, while miR-21 up-regulated tissues compared non-cancer tissues. Low levels...
Phospho-AMP-activated protein kinase (p-AMPK) and AMP-activated (AMPK) were detected by western blot. Immunofluorescence staining was used to validate changes in the levels of nuclear factor kappa B (NF-кB) p65 translocation. Mice administered intraperitoneally with calycosin one hour before anaesthesia endotracheal instillation PM 2.5. The extent lung injury evaluated H&E-stained sections. Apoptotic cells TUNEL staining.Administration increased 2.5-treated B2B a dose-dependent manner vitro....
This study aims to evaluate the clinical value of haptoglobin (Hp) and sCD163 testing for differential diagnosis pleural effusion, investigate correlation Hp with inflammatory response body.Pleural effusion samples were collected from 78 patients (38 tuberculous effusions [TPE] 40 malignant [MPE]). The concentrations in measured by enzyme-linked immunosorbent assay (ELISA).The significantly higher TPE group than MPE (P < .05). sensitivity specificity test was 82.4% 86.1%, respectively .01),...
Asphalt binder is very sensitive to temperature and exhibits bonding or lubrication effects at different temperatures. The bonding/lubrication properties of asphalt affect the mixing, compaction, service performance mixture. To analyze interface transformation behavior aggregate-asphalt systems, contact-slip test was conducted temperatures using a self-developed tester. maximum slip force used evaluate contact systems. A relational model between established, content for proposed. transition...
Abstract Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 March 15, 2020. We retrospectively demographic information, recent exposure history, symptoms or signs, comorbidity, chest computed tomographic (CT) scan X-ray results, laboratory test diagnostic classification, treatment, length...
Listeria monocytogenes (L. monocytogenes) is an important Gram-positive food-borne pathogen that severely threatens public health. A checkerboard microdilution method was performed to evaluate the synergistic effect of lithocholic acid (LCA) with Gentamicin (Genta) against L. monocytogenes. BacLight LIVE/DEAD staining, scanning electron microscopy and biofilm inhibition assays were further used explore bactericidal antibiofilm this combination on Additionally, effects LCA derivatives Genta...
Abstract Rationale: Methicillin-resistant Staphylococcus aureus (MRSA) has been established as an important cause of severe community-acquired pneumonia (CAP) with very high mortality. Panton–Valentine leukocidin (PVL) producing MRSA reported to be associated necrotizing and worse outcome. The incidence (CA-MRSA) is low, only a few CA-MRSA cases were in the last years. We present case CAP caused by PVL-positive ensuing septic shock. Patient concerns: A 68-year-old male no concerning medical...
Coronary heart disease (CHD) is closely associated with cognitive impairment, especially in severe cases of failure. However, it unclear whether cardiac systolic function plays a role the relationship between pre-existing CHD and impairment subjects without clinical failure.In total, 208 from First Affiliated Hospital Xi'an Jiaotong University were recruited June 2014 to January 2015, divided into (n = 118) non-CHD 90) groups according inclusion exclusion criteria. The global all was...
Nowadays, we have witnessed the great success of AI in various applications, including image classification, game playing, protein structure analysis, language translation, and content generation. Despite these powerful there are still many tasks our daily life that rather simple to humans but pose challenges AI. These include understanding, few-shot learning, abstract concepts, low-energy cost computing. Thus, learning from brain is a promising way can shed light on development...
This study evaluated the clinical levels of CD97 and CD55 for differential diagnosis pleural effusion.Pleural effusion samples were collected from 106 patients (55 tuberculous effusions [TPE] 51 malignant [MPE]). in measured by enzyme-linked immunosorbent assay.CD97 significantly higher TPE group than MPE (P < .001), while .001). The sensitivity specificity testing was 80.0% 60.8%, respectively, 88.2% 85.5%, respectively. Furthermore, combinatorial 90.0% 87.5%, Moreover, negatively...