A5031834137- Plant Physiology and Cultivation Studies
- Antioxidant Activity and Oxidative Stress
- Drug-Induced Adverse Reactions
- Plant Gene Expression Analysis
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Plant Molecular Biology Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Phytochemicals and Antioxidant Activities
- Biosimilars and Bioanalytical Methods
- Plant biochemistry and biosynthesis
- Per- and polyfluoroalkyl substances research
- Plant nutrient uptake and metabolism
- Plant responses to water stress
- Horticultural and Viticultural Research
- Plant Stress Responses and Tolerance
- Plant Reproductive Biology
- Dementia and Cognitive Impairment Research
- Adipose Tissue and Metabolism
- Monoclonal and Polyclonal Antibodies Research
- Pharmacological Effects and Assays
- Frailty in Older Adults
- Selenium in Biological Systems
- Cocoa and Sweet Potato Agronomy
- Postharvest Quality and Shelf Life Management
Xinjiang Medical University
2024-2025
Fifth Affiliated Hospital of Xinjiang Medical University
2024-2025
Qingdao University
2022-2024
University of Chinese Academy of Sciences
2024
Tumor Hospital of Xinjiang Medical University
2024
Wuhan Polytechnic University
2024
North China Electric Power University
2024
Southwest University
2020-2023
Fudan University
2022-2023
Wuhan University
2023
Abstract Background Plants have remarkable diversity in petal colour through the biosynthesis and accumulation of various pigments. To better understand mechanisms regulating pigmentation Lonicera japonica , we used multiple approaches to investigate changes carotenoids, anthocyanins, endogenous hormones gene expression dynamics during transitions, i.e., green bud petals (GB_Pe), white flower (WF_Pe) yellow (YF_Pe). Results Metabolome analysis showed that YF_Pe contained a much higher...
The WRKY gene family, which is one of the largest transcription factor (TF) families, plays an important role in numerous aspects plant growth and development, especially various stress responses. However, functional roles family loquat are relatively unknown. In this study, a novel gene, EjWRKY17, was characterized from Eriobotrya japonica, significantly upregulated leaves by melatonin treatment during drought stress. EjWRKY17 protein, belonging to group II localized nucleus. results...
Abstract Wild loquats (Eriobotrya japonica Lindl.) provide remarkable genetic resources for studying domestication and breeding improved varieties. Herein, we generate the first high-quality chromosome-level genome assembly of wild loquat, with 45 791 predicted protein-coding genes. Analysis comparative genomics indicated that loquat shares a common ancestor apple pear, recent whole-genome duplication event occurred in prior to its divergence. Genome resequencing showed germplasms can be...
Triploid loquats are divided into yellow- and white-fleshed cultivars. To better understand taste variations in triploid loquat fruits, we used a UPLC-ESI-QTRAP-MS/MS-based widely targeted metabolomic analysis to examine the metabolic composition of two different color fleshed with sample size 54 external validation method within confidence level P<0.05. We identified key flavor-related differentially accumulated metabolites using variable importance projection (VIP) value (VIP ≥ 1.0) fold...
Background Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors (EGFR-TKIs) in clinical use show promise but can cause AEs, impacting patients’ wellbeing and increasing costs. Methods This study utilized two methods: network meta-analysis (NMA) disproportionality analysis (DA). For NMA, we searched PubMed, Embase, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov up to 10 September 2024, for phase II/III RCTs comparing EGFR-TKI monotherapy with chemotherapy or other...
Human health risk assessment of chemicals is essential but often relies on time-consuming and animal labor-extensive procedures. Here, we develop a population-based, quantitative in vitro to vivo extrapolation (QIVIVE) approach which depended cellular effects monitored by assays, considered chemical internal concentration determined LC-MS/MS, extrapolated into target tissue through physiologically based pharmacokinetic (PBPK) modelling, assessed populational using silico modelling. By...
Waxy rice starch (St) was modified by pre-OSA esterification reaction followed ozone treatment. The molecular structure of this product (OSA-OSt) characterized, and the thermal behaviors its stabilized Pickering emulsion were evaluated.
The WUSCHEL (WUS)-related homeobox (WOX) gene family plays a crucial role in stem cell maintenance, apical meristem formation, embryonic development, and various other developmental processes. However, the identification function of WOX genes have not been reported perennial loquat. In this study, 18 EjWOX were identified loquat genome. Chromosomal localization analysis showed that located on 12 17 chromosomes. Gene structure all contain introns, which 11 untranslated regions. There are 8...
Perfluorooctane sulfonate (PFOS) and its alternative 6:2 chlorinated polyfluorinated ether (6:2 Cl-PFESA) are ubiquitous in various environmental human samples. They have been reported to hepatotoxicity effects, but the potential mechanisms remain unclear. Herein, we integrated metabolomics proteomics analysis investigate altered profiles metabolite protein levels primary hepatocytes (PHH) exposed Cl-PFESA PFOS at exposure relevant concentrations. Our results showed that exhibited higher...
Nitrogen metabolism in citrus has received increased attention due to its effects on plant growth and productivity. However, little is known about the of nitrogen fertilization young trees cultivar 'Huangguogan' (Citrus reticulata × Citrus sinensis). Here, genes encoding nitrate reductase (NR), nitrite (NiR), glutamine synthetase (GS), glutamate dehydrogenase (GDH), asparagine (AS), represented as HgNR, HgNiR, HgGS, HgGDH, HgAS, respectively, were cloned from Huangguogan. Deduced protein...
Studies of residential greenness and depression symptoms among community-dwelling older adults in China are limited. However, understanding the role can inform prevention interventions.
Dementia has become a public health priority and is irreversible. Mild cognitive impairment (MCI), an intermediate state between normal cognition dementia, the prime time for early diagnosis intervention. The activities of daily living dementia patients are usually insufficient. Therefore, continuing to explore risk factors MCI, especially influence physical activity on MCI its mechanism can enrich relevant research fields in China.For this cross-sectional study, 2,518 adults aged 60 years...
Cresyl diphenyl phosphate (CDP), a novel organophosphate ester (OPE), has been detected in various environmental and human samples. However, there is very limited knowledge regarding its toxicity, mechanisms of action, potential health risks. Using new alternative methods (NAMs), across the molecular interactions, signaling pathways, cell functions, animal effects, population risks, we investigated adipogenic effects associated risks CDP legacy OPE triphenyl (TPHP) by acting on peroxisome...
Organic food-waste is an ever growing environmental, economic, and social problem. One way to address this problem find new ways valorise food waste in a circular economical manner. In study, the concept of separating from at its source eateries was applied obtain separated fish residues general our university's canteen. This study first known attempt use as soil amendments for biosolarization (SBS), treatment method which environment-friendly alternative chemical fumigation soil. unique...